Over the past 30 years, several microbiology laboratories in Singapore General Hospital
developed extensive collections of Risk Group 3 (RG) agents. With the opening of a new,
central diagnostic laboratory, the pathogenic specimens had to be relocated to the
state-of-the-art Biosafety Level 3 (BSL-3) facility without disruption of laboratory
diagnostic work. A risk assessment of all aspects of the task was conducted and
communicated, and the planning, preparation, and dry run are described.