Pyoderma Gangrenosum is cutaneous manifestation of a systemic problem that should be systematically diagnosed and managed with care. When such lesions appear on legs, it is important to study and treat the systematic problem.
Burnsting LA, Goeckrman WH, O’Leary PA. Pyoderma (ecthyma) gangrenosum: clinical and experimental observations in five cases occurring in adults. Arch Dermatol1930;22:655-690.
2.
Johnson ML, Wilson HTH. Skin lesions in ulcerative colitis. Gut1969;10:255-263.
3.
Mir-Madjlessi SH, Taylor JS, Farmer RG.Clinical course and evolution of erythema nodosum and pyoderma gangrenosum in chronic ulcerative colitis: a study of 42 patients. Am J Gastroenterol1985;80:615-620.
4.
Samitz MH, Greenberg MS.Skin lesion in association with ulcerative colitis. Gastroenterology1951;19:476-479.
5.
Powell FC, Schroeter AL, Su WPD, et al.Pyoderma gangrenosum: a review of 86 patients. Q J Med1985;55:173-186.
6.
Powell FC, Perry HO.Pyoderma gangrenosum in childhood. Arch Dermatol1984;120:757-761.
7.
Powell FC, Su WPD, Perry HO.Pyoderma gangrenosum: classification and management. J Am Acad Dermatol1996;34:395-409.
8.
Greenstein AJ, Janowitz HD, Sachar DB.The extra-intestinal complications of Crohn’s disease and ulcerative colitis: a study of 700 patients. Medicine (Balt)1976;55:401-412.
9.
Cox NH, Peebler-Brown PA, Mackie RM.Pyoderma gangrenosum occurring 10 years after procto-colectomy for ulcerative colits. Br J Hosp Med1986;36:363.
10.
Gilman AL, Cohen BA, Urbach, et al.Pyoderma gangrenosum as a manifestation of leukaemia in childhood. Paediatrics1988;81:846-848.
11.
Ho KK-L, Otridge B, Vandenberg E, et al.Pyoderma gangrenosum, polycythaemia rubra vera and development of leukaemia. J Am Acad Dermatol1992;27:804-808.
Kitahama A, Roand PY, Kerstein MD.Pyoderma gangrenosum with cutaneous T-cell lymphoma manifested as lower extremity ulcers: case reports. Angiology1991;42:498-503.
14.
Jacobs P, Palmer S, Gordon-Smith EC.Pyoderma gangrenosum in myelodysplasia and acute leukaemia. Postgrad Med J1985;61:689-694.
15.
Harland CC, Millard LG.Pyoderma gangrenosum—a complication of chronic venous leg ulceration?Clin Exp Dermatol1993;18:545-547.
16.
Holt PJA, Davies MG, Sanders KC, et al.Pyoderma gangrenosum: clinical and laboratory findings in 15 patients with special reference to polyarthritis. Medicine1980;59:114-133.
17.
Percival GH.Pyoderma gangrenosum: the histology of the primary lesion. Br J Dermatol1957;69:130-136.
18.
Rosenberg A.The Schwartzmann phenomenon: a review with a consideration of possible dermatological manifestations. Br J Dermatol1953;65:389-391.
19.
Meyer K, Gelhorn A, Prudden JF.Lysozyme activity in ulcerative alimentary disease II. Am J Med1948;5:496-502.
20.
Strongton RB.Enzymatic cytolysis of epithelium by filtrates from patients with ulcerative colitis. J Invest Dermatol1953;20:353-356.
21.
Delescluse J, Bast C, Achten G.Pyoderma gangrenosum with altered cellular immunity and dermatonecrotic factor. Br J Dermatol1972;87:529-532.
22.
Marcussen PV.Hypogammaglobulinaemia in pyoderma gangrenosum. J Invest Dermatol1988;18:574-576.
23.
Berbis P, Mege JL, Capo C, et al.Hypoimmunegloulin E and impaired neutrophil function in a case of pyoderma gangrenosum: effect of Clofamazine. J Am Acad Dermatol1988;18:574-576.
24.
Lazarus GS, Goldsmith LA, Rocklin RE, et al.Pyoderma gangrenosum, altered delayed hypersensitivity and polyarthritis. Arch Dermatol1972;105:46-51.
25.
Nerella P, Damela A, Guido A, et al.Leukocyte chaemotaxis and pyoderma gangrenosum. Int J Dermatol1985;24:45-47.
26.
Bentley-Phillips CB, Cooper RC, Hallett AF.Pharmacological modulation of neutrophil phagocytic functionin a patient with recurrent sepsis, pyoderma gangrenosum and impaired phagocytosis. Br J Dermatol1982;106:687-695.
27.
Check IJ, Ellington EP, Moreland A, et al.T-helper-suppressor cell imbalance in pyoderma gangrenosum with relapsing polychondritis and corneal keratolysis. Am J Clin Pathol1983;80:396-399.
Peachy RDG. Pyoderma gangrenosum of scalp. Br J Dermatol1974;90:106-108.
40.
Sanders CJG, Hulsmans RFHJ. Successful treatment of pyoderma gangrenosum with topical 5-Aminosalicylic acid. Cutis1993;51:262-264.
41.
Johnson RB, Lazarus GS.Pulse therapy: therapeutic efficacy in the treatment of pyoderma gangrenosum. Arch Dermatol1982;118:76-84.
42.
Bocanegra TS, Castaneda MD, Espinoza LR, et al.Sudden death after methyl prednisolone pulse therapy (letter). Ann Intern Med1981;95:122.
43.
Freedman MD, Schhocket AL, Chapel L, et al.Anaphylaxis and intravenous methyl prednisolone administration. JAMA1981;245: 607-608.
44.
Curley RK, Macfarlane AW, Vickers CFH. Pyoderma gangrenosum treated with cyclosporin A. Br J Dermatol1985;113: 601-604.
45.
Abu-Elmagd K, Jegasothy BV, Acherman CD, et al.Efficacy of FK506 in the treatment of recalcitrant pyoderma gangrenosum. Transplant Proc1991;23:3328-3329.
46.
Mazzone A, Cusa C, Mazzucchelli I, et al.Pyoderma gangrenosum complicating ulcerative colitis: an alternative treatment with Iloprost. Curr Ther Res1999;60:357-362.
47.
de Imus G, Golomb C, Wilkel C, et al.Accelerated healing of pyoderma gangrenosum treated with bioengineered skin and concomitant immunosuppressive therapy. J Am Acad Dermatol2001;44:61-66.