This case study describes the effectiveness of cognitive-behavioral therapy for nicotine dependence among smokers with comorbid alcohol dependence and severe respiratory difficulties. Although clinical practice guidelines exist for the treatment of nicotine dependence, smokers with complicated psychological and medical histories remain resilient to recommended treatments. Successfulsmoking cessation programs for these patients require a comprehensive biopsychosocial assessment as well as a tailored treatment approach. A theoretical and empirically based rationale for cognitive-behavioral treatment is provided followed by the development of a case conceptualization, course of treatment, use of assessment data, and recommendations.
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