Primary Progressive Aphasia: Clinical,Imaging,and Neuropathological Findings

Abstract

Primary Progressive Aphasia (PPA) is a neurodegenerative disorder initially presenting with progressive language imapirment. This article provides a clinically oriented review of PPA. Different clinical presentations and imaging findings of 3 subtypes, agrammatic, semantic and logopenic, are presented. Underlying neuropathology, medical and social management aspects of these patients are reviewed.

Keywords

aphasia primary progressive aphasia neurodegenerative disease dementia

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