Vibro-acoustography has gained interest in the recent years as a new modality for medical imaging. This method is based on low-frequency vibrations induced in the object by the radiation force of ultrasound. This paper focuses on potential applications of vibro-acoustography in breast imaging, including detection of microcalcifications, detection of arterial calcifications, and soft tissue imaging. In addition, we will briefly discuss our recent results of in vivo breast vibro-acoustography. Future developments and potential impact of vibro-acoustography in breast imaging are also discussed.
AbeloffM. D., LichterA. S., NiederhuberJ. E., PierceL. J., and LoveR. R.Breast, in: Clinical Oncology, 2nd Ed., pp 2051–2138. Eds., AbeloffM. D., ArmitageJ. O., LichterA. S. and NiederhuberJ. E.. Churchill Livingstone, New York, NY (2000).
2.
LesterS. C. and CortanR. S.The Breast, in: Robins Pathologic Basis of Diseases, 6th ed., pp 1093–1117. Eds., CortanR. S., KumarV., and CollinT.. W. B. Saunders, Philadelphia, PA (1999).
3.
DoddG. D.American Cancer Society Guidelines on Screening for Breast Cancer. Cancer69, 1885–1887 (1992).
4.
American Cancer Society Workshop on Guidelines and Screening for Breast Cancer Proceedings. Cancer Suppl.69, 188 (1991).
5.
(Anonymous Authors). Screening Recommendations of the Forum Panel. J. Gerontol.47 (5) (1992).
6.
FletcherS. W., BlackW. and HarrisW. R.Report of the International Workshop on Screening for Breast Cancer. J. Natl. Cancer Inst.85, 1644–56 (1993).
7.
KerlikowskeK.Effect of Age, Breast Density, and Family History on the Sensitivity of First Screen Mammography. JAMA276, 33–37 (1996).
8.
LehmanC. D., WhiteE., PeacockS., and UrbanN.Effect of Age and Breast Density on Screening Mammograms with False-positive Findings. Am. J. Roentgenol.173, 1651–1655 (1999).
9.
LibermanL., AbramsonA. F., SquiresF. B.The Breast Imaging Reporting and Data System-positive Predictive Value of Mammographic Features and Final Assessment Categories. Am. J. Roentgenol.171, 35–40 (1998).
10.
FatemiM. and GreenleafJ. F.Ultrasound Stimulated Vibro-acoustic Spectroscope. Science280, 82–85 (1998).
11.
FatemiM. and GreenleafJ. F.Vibro-acoustography. An Imaging Modality Based on Ultrasound Stimulated Acoustic Emission. Proc. Natl. Acad. Sci. USA.96, 6603–6608 (1999).
12.
GreenleafJ. F., EhmanR. L., FatemiM., and MuthupillaiR.Imaging Elastic Properties of Tissue, in Ultrasound in Medicine (Medical Science Series), pp 263–277. Eds., DuckF. A., BakerA. C. and StarritH. C.. Institute of Physics Publishing, Bristol, England (1998).
13.
FatemiM. and GreenleafJ. F.Probing the Dynamics of Tissue at Low Frequencies with the Radiation Force of Ultrasound. Phys. Med. Biol.45, 1449–1464 (2000).
14.
FatemiM., ManducaA., and GreenleafJ. F.Imaging Elastic Properties of Biological Tissues by Low-frequency Harmonic Vibration. Proc. of IEEE91, 1503–1517 (2003).
15.
FatemiM. and GreenleafJ. F.Imaging the Viscoelastic Properties of Tissue, in Topics in Applied Physic, Vol. 84, pp 257–275. Eds., FinkM., MontagnerJ-P., and TourinA.. Springer, Verlog, Heidelberg, Berlin (2002).
16.
FatemiM. and GreenleafJ. F.Imaging and Evaluating the Elastic Properties of Biological Tissues. BMUS Bulletin (The British Medical Ultrasound Society)8, 16 and 18 (2000).
AlizadA., FatemiM., WoldL. E.Performance of Vibro-acoustography in Detecting of Microcalcifications in Excised Human Breast Tissue: A Study on 74 Breast Tissue Samples. IEEE Trans. Med. Imag.23, 307–312 (2004).
19.
SilvaG. T., GreenleafJ. F., and FatemiM.Linear Array Beamforming for Vibro-acoustography: A Numerical Simulation Study. Ultrasonic Imaging25, 1–17 (2004).
20.
GroverS. A., CoupalL., and HuX. P.Identifying Adults at Increased Risk of Coronary Disease. How Well do the Current Cholesterol Guidelines Work?JAMA274, 801–806 (1995).
21.
CoxJ., SimpsonW., and WalshawD.An Interesting Byproduct of Screening: Assessing the Effect of HRT on Arterial Calcification in the Female Breast. J. Med. Screen.9, 38–39 (2002).
22.
SitrukW. R.Cardiovascular Risk at the Menopause: The Role of Sexual Steroids. Horm. Res.43, 58–63 (1995).
23.
BaumJ., ComstockC., and JosephL.Intra-mammary Arterial Calcifications Associated with Diabetes. Radiology136, 61–62 (1980).
24.
SicklesE. A. and GalvinH. B.Breast Arterial Calcification in Association with Diabetes Mellitus: Too Weak a Correlation to Have Clinical Utility. Radiology155, 577–579 (1985).
25.
MoshyediA. C., PuthawalaA. H., KurlandR. J., and O'LearyD. H.Breast Arterial Calcification: Association with Coronary Artery Disease. Work in Progress. Radiology194, 181–183 (1995).
26.
KemmerenJ. M., BeijerinckD., van NoordP. A.Breast Arterial Calcifications: Association with Diabetes Mellitus and Cardiovascular Mortality. Radiology201, 75–78 (1996).
27.
KemmerenJ. M., van NoordP. A., BeijerinckD.Arterial Calcification Found on Breast Cancer Screening Mammograms and Cardiovascular Mortality in Women. The DOM Project. Am. J. Epidemiol.147, 333–341 (1998).
28.
van NoordP. A., BeijerinckD., KemmerenJ. M.Mammograms may Convey More than Breast Cancer Risk: Breast Arterial Calcification and Arterio-sclerotic Related Diseases in Women of the DOM Cohort. Eur. J. Cancer Prevention5, 483–487 (1996).
29.
DoergerK. M., WhaleyD. H., BergerP. B.Breast Arterial Calcification Detected on Mammography is a Risk Factor for Coronary Artery Disease. Radiology225, 553 (2003).
30.
AlizadA., FatemiM., WhaleyD. H.Application of Vibro-acoustography for Detection of Calcified Arteries in Breast Tissues. J. Ultrasound Med.23, 267–273 (2004).
31.
AlizadA., WoldL. E., GreenleafJ. F.Imaging Mass Lesions by Vibro-acoustography: Modeling and Experiment. IEEE Trans. Med. Imag.23, 1087–1093, 2004.
