Carotid Artery Plaque Morphology: Ultrasonographic Appearance and its Role in the Development of Cerebrovascular Symptoms

Ruffer MA On arterial lesions found in Egyptian mummies (1580 B.C.-525 A.D.). J Pathol 15:453-462, 1911.

Savory WS Case of a young woman in whom the arteries of both upper extremities and of the left side of the neck were throughout completely obliterated. In Thompson JE. Surgery for Cerebrovascular Insufficiency (Stroke) With Special Emphasis on Carotid Endarterectomy. Springfield: Charles C. Thomas, 1968, p 5.

Chiari H. Uber das Verhalten des Teilungsungswinhals der Carotis Communis bei der Endarteritis Chronica Deformans. Verh Dtsch Pathol Ges 9:326-330, 1905.

Fisher M. Occlusion of the internal carotid artery. Arch Neurol Psychiatry 5:346-377, 1951.

Moore WS , Hall AD Ulcerated atheroma of the carotid artery: A cause of transient cerebral ischemia . Am J Surg 116:237-242, 1968.

Imparato AM , Riles TS , Gorstein F. Carotid bifurcation plaque: Pathologic findings associated with cerebral ischemia . Stroke 10:238-245, 1979.

Lusby RJ , Ferrell LD , Ehrenfeld WK , et al. Carotid plaque hemorrhage: Its role in production of cerebral ischemia. Arch Surg 117:1479-1488, 1982 .

Persson AV , Robichaux WT , Silverman M. The natural history of carotid plaque development. Arch Surg 118:1048-1052, 1983.

Imparato AM , Riles TS , Mintzer R. , et al. The importance of hemorrhage in the relationship between gross morphologic characteristics and cerebral symptoms in 376 carotid artery plaques . Ann Surg 197:195-203, 1983.

Zarins CK , Giddens DP , Bharadvaj BK , et al. Carotid bifurcation atherosclerosis: Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res 53:502-514, 1983.

Barber FE Duplex scanner II: For simultaneous imaging of artery tissues and flow. In Proceedings of the Ultrasonic Symposium, IEEE 74 CHO 896-ISU. New York: Institute of Electrical and Electronic Engineers Inc., 1974.

Goodson SF , Flanigan DP , Bishara RA , et al. Can carotid duplex scanning supplant arteriography in patients with focal carotid territory symptoms? J Vasc Surg 5:551-557, 1987.

Moore WS , Ziomek S. , Quinones-Baldrich WJ , et al. Can clinical evaluation and noninvasive testing substitute for arteriography in the evaluation of carotid artery disease? Ann Surg 208:91-94, 1988.

Davies MJ , Woolf N. Atheroma: Atheroscleroses in Ischaemic Heart Disease, vol I. The Mechanisms . London: Science Press, 1990.

Ross R. The pathogeneses of atherosclerosis—An update. N Engl J Med 314:488-500, 1986.

Lusby RJ Lesions, dynamics, and pathogenetic mechanisms responsible for ischemic events in the brain. In Moore WS , ed. Surgery for Cerebrovascular Disease. New York : Churchill Livingstone, 1987, pp 51-76.

Lusby RJ , Woodcock JP , Machleder HI , et al. Transient ischaemic attacks: The static and dynamic morphology of the carotid artery bifurcation. Br J Surg 69:41-44, 1982.

White A. , McCarty K. , Morgan R. , et al. Investigation of carotid plaque motility. Proceedings of BES Meeting. Glasgow, Scotland: 1987.

Woodcock JP Characterization of the atheromatous plaque in the carotid arteries. Clin Phys Physiol Meas 10:45-49, 1989.

Paterson JC Capillary rupture with intimal hemorrhage as a causative factor in coronary thrombosis. Arch Pathol 25:474-487, 1938.

Svindland A. , Torvik A. Atherosclerotic carotid disease in asymptomatic individuals. Acta Neurol Scand 78:506-517, 1988.

Ammar AD , Wilson RL , Travers H. , et al. Intraplaque hemorrhage: Its significance in cerebrovascular disease. Am J Surg 148:840-842, 1984.

Fisher CM , Ojemann RG A clinico-pathologic study of carotid endarterectomy plaques. Rev Neurol 142:573-589, 1986.

Bassiouny HS , Davis H. , Massawa N. , et al. Critical carotid stenoses: Morphologic and chemical similarity between symptomatic and asymptomatic plaques. J Vasc Surg 9: 202-212, 1989.

Hertzer NR , Beven EG , Benjamin SP Ultramicroscopic ulcerations and thrombi of the carotid bifurcation . Arch Surg 112:1394-1402, 1977 .

Pessin MS , Duncan GW , Mohr JP , et al. Clinical and angiographic features of carotid transient ischemic attacks. N Engl J Med 296:358-362, 1977.

Thiele BL , Young JV , Chikos PM , et al. Correlation of arteriographic finding and symptoms in cerebrovascular disease. Neurology 30:1041-1046, 1980 .

Kohler TR , Zierler RE , Strandness DE Duplex scanning and spectral analysis. In Moore WS , ed. Surgery for Cerebrovascular Disease. New York: Churchill Livingstone, 1987, pp 353-373.

Rubin JR , Bondi JA , Rhodes RS Duplex scanning versus conventional arteriography for the evaluation of carotid artery plaque morphology Surgery 102:749-755, 1987.

Zwiebel WJ High resolution carotid sonography. Semin Ultrasound 2:316-322, 1981.

Cooperberg T. , Robertson W. , Fry P. , et al. High resolution real-time ultrasound of the carotid bifurcation. AJNR 3:13-17, 1982.

Reilly LM , Lusby RJ , Hughes L. , et al. Carotid plaque histology using real-time ultrasonography. Am J Surg 146:188-193, 1983.

Wolverson MK , Bashiti HM , Peterson GJ Ultrasonic tissue characterization of atheromatous plaques using a high resolution real time scanner. Ultrasound Med Biol 9:599-609, 1983.

O'Donnell TF , Erdoes L. , Mackey WC , et al. Correlation of B-mode ultrasound imaging and arteriography with pathologic findings at carotid endarterectomy. Arch Surg 120:443-449, 1985.

O'Donnell TF , Callow AD , Scott G. , et al. Ultrasound characteristics of recurrent carotid disease: Hypothesis explaining the low incidence of symptomatic recurrence . J Vasc Surg 2: 26-41, 1985.

Sterpetti AV , Schultz RD , Feldhaus RJ , et al. Natural history of recurrent carotid artery disease. Surg Gynecol Obstet 168:217-223, 1989.

Widder B. , Paulat K. , Hackspacher J. , et al. Morphological characterization of carotid artery stenoses by ultrasound duplex scanning. Ultrasound Med Biol 16:349-354, 1990.

Avril G. , Batt M. , Guidon R. , et al. Carotid endarterectomy plaques: Correlations of clinical and anatomic findings. Ann Vasc Surg 5:50-54, 1991.

O'Leary DH , Bryan FA , Goodison MW , et al. Measurement variability of carotid atherosclerosis: Real-time (B-mode) ultrasonography and angiography. Stroke 18:1011-1017, 1987 .

Ricotta JJ Plaque characterization by B-mode scan. Surg Clin North Am 70:191-199, 1990.

Bluth EI , McVay LV , Merritt CRB , et al. The identification of ulcerative plaque with high resolution duplex carotid scanning. J Ultrasound Med 7:73-76, 1988.

Hennerici M. , Rautenberg W. , Trockel U. , et al. Spontaneous progression and regression of small carotid atheroma. Lancet 1:1415-1419, 1985.

O'Hollerhan LW , Kennelly MM , McClurken M. , et al. Natural history of asymptomatic carotid plaque. Am J Surg 154:659-662, 1987.

Sterpetti AV , Schultz RD , Feldhaus RJ , et al. Ultrasonographic features of carotid plaque and the risk of subsequent neurologic deficits . Surgery 104:652-660, 1988.

Leahy AL , Grouden MC , McBride KD , et al. Duplex scanning for noninvasive assessment of both carotid luminal diameter and atheromatous plaque morphology. Ann Vasc Surg 1: 465-468, 1986.

Langsfeld M. , Gray-Weale AC , Lusby RJ The role of plaque morphology and diameter reduction in the diameter of new symptoms in asymptomatic carotid arteries . J Vasc Surg 9: 548-557, 1989.

Steffen CM , Grav-Weale AC , Bvrne KE , et al. Carotid artery atheroma and ultrasound appearance in symptomatic and asymptomatic vessels. Aust N Z J Surg 59:529-534, 1989.

Dempsey RJ , Diana AL , Moore RW Thickness of carotid artery atherosclerotic plaque and ischemic risk . Neurosurgery 27:343-348, 1990.

North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325:445-453, 1991.

Bendick PJ , Glover JL , Hankin R. , et al. Carotid plaque morphology: Correlation of duplex sonography with histology. Ann Vasc Surg 2:6-13, 1988.