FreilingerTMSchindlerASchmidtCPrevalence of nonstenosing, complicated atherosclerotic plaques in cryptogenic stroke. JACC Cardiovasc Imaging. 2012;5:397–405.
2.
MozaffarianDBenjaminEJGoASHeart Disease and Stroke Statistics—2016 Update: A report from the American Heart Association. Circulation. 2016;133:e38–e60.
3.
O’BrienMChandraA. Carotid revascularization: risks and benefits. Vasc Health Risk Manag. 2014;10:403–416.
4.
RibichiniFTomaiFCastriotaFThe gap between vascular interventions and vascular medicine. EuroIntervention. 2010;6:25–27.
5.
de WeerdMGrevingJPHedbladBPrediction of asymptomatic carotid artery stenosis in the general population: identification of high-risk groups. Stroke. 2014;45:2366–2371.
6.
FisherMPaganini-HillAMartinACarotid plaque pathology: thrombosis, ulceration, and stroke pathogenesis. Stroke. 2005;36:253–257.
7.
SillesenHAmarencoPHennericiMGAtorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2008;39:3297–3302.
8.
CapodannoDAlbertsMAngiolilloDJ. Antithrombotic therapy for secondary prevention of atherothrombotic events in cerebrovascular disease [published online August4, 2016]. Nat Rev Cardiol. doi:10.1038/nrcardio.2016.111.
9.
BrugtsJJNinomiyaTBoersmaEThe consistency of the treatment effect of an ACE-inhibitor based treatment regimen in patients with vascular disease or high risk of vascular disease: a combined analysis of individual data of ADVANCE, EUROPA, and PROGRESS trials. Eur Heart J. 2009;30:1385–1394.
10.
NaylorAR. What is the current status of invasive treatment of extracranial carotid artery disease?Stroke. 2011;42:2080–2085.
11.
MusialekPMazurekATrystulaMNovel PARADIGM in carotid revascularisation: Prospective evaluation of All-comer peRcutaneous cArotiD revascularisation in symptomatic and Increased-risk asymptomatic carotid artery stenosis using CGuard™ MicroNet-covered embolic prevention stent system. EuroIntervention. 2016;12:e658–e670.
12.
KwolekCJJaffMRLealJIResults of the ROADSTER multicenter trial of transcarotid stenting with dynamic flow reversal. J Vasc Surg. 2015;62:1227–1234.
13.
BosiersMDelooseKTorselloGThe CLEAR-ROAD study: evaluation of a new dual layer micromesh stent system for the carotid artery. EuroIntervention. 2016;12:e671–e676.
14.
SabetiSSchlagerOExnerMProgression of carotid stenosis detected by duplex ultrasonography predicts adverse outcomes in cardiovascular high-risk patients. Stroke. 2007;38:2887–2994.
15.
ConradMFBoulomVMukhopadhyaySProgression of asymptomatic carotid stenosis despite optimal medical therapy. J Vasc Surg. 2013;58:128–135.
16.
AbbottAL. Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis. Stroke. 2009;40:e573–e583.
17.
AbbottALAdelmanMAAlexandrovAVWhy calls for more routine carotid stenting are currently inappropriate: an international, multispecialty, expert review and position statement. Stroke. 2013;44:1186–1190.
18.
KakkosSKNicolaidesANCharalambousIPredictors and clinical significance of progression or regression of asymptomatic carotid stenosis. J Vasc Surg. 2014;59:956–967.
19.
MusialekPTraczWTekieliLMultimarker approach in discriminating patients with symptomatic and asymptomatic atherosclerotic carotid artery stenosis. J Clin Neurol. 2013;9:165–175.
20.
de WeerdMGrevingJPHedbladBPrevalence of asymptomatic carotid artery stenosis in the general population: an individual participant data meta-analysis. Stroke. 2010;41:1294–1297.
21.
CapodannoDAngiolilloDJ. Diabetes mellitus: the scary killer haunting silently. EuroIntervention. 2010;5:879–881.
22.
AbbottA. Asymptomatic carotid artery stenosis—it’s time to stop operating. Nat Clin Pract Neurol. 2008;4:4–5.
23.
StreiflerJY. Asymptomatic carotid stenosis: intervention or just stick to medical therapy—the case for medical therapy. J Neural Transm (Vienna). 2011;118:637–640.
24.
AbbottALParaskevasKIKakkosSKSystematic review of guidelines for the management of asymptomatic and symptomatic carotid stenosis. Stroke. 2015;46:3288–3301.
25.
HartRGNgKH. Stroke prevention in asymptomatic carotid artery disease: revascularization of carotid stenosis is not the solution. Pol Arch Med Wewn. 2015;125:363–369.
26.
HackamDGKapralMKWangJTMost stroke patients do not get a warning: A population-based cohort study. Neurology. 2009;73:1074–1076.
PaulSLSturmJWDeweyHMLong-term outcome in the North East Melbourne Stroke Incidence study: predictors of quality of life at 5 years after stroke. Stroke. 2005;36:2082–2086.
29.
ParaskevasKINicolaidesANVeithFJ. Carotid endarterectomy may be required in addition to best medical treatment for some patient subgroups with asymptomatic carotid stenosis. Vascular. 2015;23:62–64.
30.
HallidayAMansfieldAMarroJPrevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurologic symptoms: randomised controlled trial. Lancet. 2004;363:1491–1502.
31.
HallidayAHarrisonMHayterE10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): A multicentre randomised trial. Lancet. 2010;376:1074–1084.
32.
GoldsteinLBBushnellCDAdamsRJGuidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:517–584.
33.
MarquardtLGeraghtyOCMehtaZLow risk of ipsilateral stroke in patients with asymptomatic carotid stenosis on best medical treatment: a prospective, population-based study. Stroke. 2010;41:e11–e17.
34.
ConstantinouJJayiaPHamiltonG. Best evidence for medical therapy for carotid artery stenosis. J Vasc Surg. 2013;58:1129–1139.
35.
AlmekhlafiMAMorrishWFHillMD. Carotid artery stenting: the dust has not yet settled. Can J Cardiol. 2014;30:14–15.
36.
MusialekP. MicroNet covered embolic prevention carotid stent system: From CARENET and PARADIGM studies to routine clinical practice. Presented at: The VEITH Conference; November 20, 2015; New York, NY. http://www.veithsymposium.org/abstracts/2015/vei/2587.pdf. Accessed August 20, 2016.
37.
AbbottAL. Current medical intervention alone is now the best solution for asymptomatic carotid stenosis. Eur J Vasc Endovasc Surg. 2010;40:678–679.
38.
SerruysPW. Meta-analysis: don’t do what I did. EuroIntervention. 2016;12:e535.
39.
NaylorARSchroederTVSillesenH. Clinical and imaging features associated with an increased risk of late stroke in patients with asymptomatic carotid disease. Eur J Vasc Endovasc Surg. 2014;48:633–640.
40.
SpenceJDCoatesVLiHEffects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol. 2010;67:180–186.
41.
MasJLArquizanCCalvetDLong-term follow-up study of endarterectomy versus angioplasty in patients with symptomatic severe carotid stenosis trial. Stroke. 2014;45:2750–2756.
42.
BonatiLHDobsonJFeatherstoneRLLong-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial. Lancet. 2015;385:529–538.
43.
BrottTGHowardGRoubinGSLong-term results of stenting versus endarterectomy for carotid-artery stenosis. N Engl J Med. 2016;374:1021–1031.
44.
RosenfieldKMatsumuraJSChaturvediSRandomized trial of stent versus surgery for asymptomatic carotid stenosis. N Engl J Med. 2016;374:1011–1020.
45.
FairmanRGrayWAScicliAPThe CAPTURE registry: analysis of strokes resulting from carotid artery stenting in the post approval setting: timing, location, severity, and type. Ann Surg. 2007;246:551–556.
46.
De DonatoGSetacciFSirignanoPOptical coherence tomography after carotid stenting: Rate of stent malapposition, plaque prolapse and fibrous cap rupture according to stent design. Eur J Vasc Endovasc Surg. 2013;45:579–587.
47.
LiuRJiangYXiongYAn optical coherence tomography assessment of stent strut apposition based on the presence of lipid-rich plaque in the carotid artery. J Endovasc Ther. 2015;22:942–949.
48.
SchoferJArendtMTüblerTLate cerebral embolization after emboli-protected carotid artery stenting assessed by sequential diffusion-weighted magnetic resonance imaging. JACC Cardiovasc Interv. 2008;1:571–577.
49.
StabileEGiuglianoGCremonesiAImpact on outcome of different types of carotid stent: results from the European Registry of Carotid Artery Stenting. EuroIntervention. 2016;12:e265–e270.
50.
TietkeMJansenO. Cerebral protection vs. no cerebral protection: timing of stroke with CAS. J Cardiovasc Surg (Torino). 2009;50:751–760.
51.
MasJLTrinquartLLeysDEndarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol. 2008;7:885–892.
52.
ParaskevasKIMikhailidisDPVeithFJ. Mechanisms to explain the poor results of carotid artery stenting (CAS) in symptomatic patients to date and options to improve CAS outcomes. J Vasc Surg. 2010;52:1367–1375.
53.
NikasDReithWSchmidtAProspective, multicenter European study of the GORE flow reversal system for providing neuroprotection during carotid artery stenting. Catheter Cardiovasc Interv. 2012;80:1060–1068.
54.
AnselGMHopkinsLNJaffMRSafety and effectiveness of the INVATEC MO.MA proximal cerebral protection device during carotid artery stenting: results from the ARMOUR pivotal trial. Catheter Cardiovasc Interv. 2010;76:1–8.
55.
MontorsiPGalliSRavagnaniPMCarotid artery stenting with proximal embolic protection via a transradial or transbrachial approach: pushing the boundaries of the technique while maintaining safety and efficacy. J Endovasc Ther. 2016;23:549–560.
56.
PinterLRiboMLohCSafety and feasibility of a novel transcervical access neuroprotection system for carotid artery stenting in the PROOF Study. J Vasc Surg. 2011;54:1317–1323.
57.
LealIOrgazAFloresÁA diffusion-weighted magnetic resonance imaging-based study of transcervical carotid stenting with flow reversal versus transfemoral filter protection. J Vasc Surg. 2012;56:1585–1590.
58.
ParaskevasKIVeithFJParodiJC. Commentary: Transcervical carotid artery stenting (CAS) with flow reversal: a promising technique for the reduction of strokes associated with CAS. J Endovasc Ther. 2016;23:255–257.
59.
StabileESanninoASchiattarellaGGCerebral embolic lesions detected with diffusion-weighted magnetic resonance imaging following carotid artery stenting: a meta-analysis of 8 studies comparing filter cerebral protection and proximal balloon occlusion. JACC Cardiovasc Interv. 2014;7:1177–1183.
60.
PieniazekPMusialekPKablak-ZiembickaACarotid artery stenting with patient- and lesion-tailored selection of the neuroprotection system and stent type: early and 5-year results from a prospective academic registry of 535 consecutive procedures (TARGET-CAS). J Endovasc Ther. 2008;15:249–262.
61.
SchoferJMusiałekPBijuklicKA prospective, multicenter study of a novel mesh-covered carotid stent: The CGuard CARENET trial (Carotid Embolic Protection Using MicroNet). JACC Cardiovasc Interv. 2015;8:1229–1234.
62.
WissgottCSchmidtWBrandt-WunderlichCClinical results and mechanical properties of the CGUARD double-layered embolic prevention stent. J Endovasc Ther. 2017;24:126–133.
63.
SchönholzCYamadaRMontgomeryWFirst-in-man implantation of a new hybrid carotid stent to prevent periprocedural neurologic events during carotid artery stenting. J Endovasc Ther. 2014;21:601–604.
64.
Hopf-JensenSMarquesLPreißMInitial clinical experience with the micromesh Roadsaver carotid artery stent for the treatment of patients with symptomatic carotid artery disease. J Endovasc Ther. 2015;22:220–225.
65.
WissgottCSchmidtWBrandt-WunderlichCPreliminary clinical results and mechanical behavior of a new double-layer carotid stent. J Endovasc Ther. 2015;22:634–639.
66.
PlessersMVan HerzeeleIHemelsoetDTranscervical carotid stenting with dynamic flow reversal demonstrates embolization rates comparable to carotid endarterectomy. J Endovasc Ther. 2016;23:249–254.
67.
MusialekP. Mesh-covered stents for carotid intervention: rationale, device designs, imaging, and data to date. Presented at: Transcatheter Cardiovascular Therapeutics; October 14, 2015; San Francisco, CA. http://www.tctmd.com/show.aspx?id=132421. Accessed August 20, 2016.
68.
ParkKYKimDIKimBMIncidence of embolism associated with carotid artery stenting: open-cell versus closed-cell stents. J Neurosurg. 2013;119:642–647.
69.
BijuklicKWandlerAHaziziFThe PROFI study (Prevention of Cerebral Embolization by Proximal Balloon Occlusion Compared to Filter Protection During Carotid Artery Stenting): a prospective randomized trial. J Am Coll Cardiol. 2012;59:1383–1389.
70.
LinPHBushRLPedenEKCarotid artery stenting with neuroprotection: assessing the learning curve and treatment outcome. Am J Surg. 2005;190:850–857.
71.
RogersRKGandhiSRosenfieldK. Carotid artery stenting versus carotid endarterectomy for treatment of asymptomatic carotid disease. Interv Cardiol Clin. 2014;3:63–72.
72.
NerlaRCastriotaFMicariACarotid artery stenting with a new-generation double-mesh stent in three high-volume Italian centres: clinical results of a multidisciplinary approach. EuroIntervention. 2016;12:e677–e683.
73.
AmorosoGVosNSVan derHeyden JAA prospective, postmarket study with the MGuard Prime Embolic Protection Stent in ST-segment elevation myocardial infarction: the International MGuard Prime Observational Study (IMOS Prime). Catheter Cardiovasc Interv. 2015;86(suppl 1):S28–S33.
74.
StoneGWAbizaidASilberSProspective, randomized, multicenter evaluation of a polyethylene terephthalate MicroNet mesh-covered stent (MGuard) in ST-segment elevation myocardial infarction: The MASTER trial. J Am Coll Cardiol. 2012;60:1975–1984.
75.
FröbertOSarnoGJamesSKEffect of stent inflation pressure and post-dilatation on the outcome of coronary artery intervention. A report of more than 90,000 stent implantations. PLoS One. 2013;8:e56348.
76.
JanuaryCTWannLSAlpertJS2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1–e76.
77.
BartusKHanFTBednarekJPercutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience. J Am Coll Cardiol. 2013;62:108–118.
78.
NoelckNPapakJFreemanMEffectiveness of left atrial appendage exclusion procedures to reduce the risk of stroke: a systematic review of the evidence. Circ Cardiovasc Qual Outcomes. 2016;9:395–405.
79.
SetacciCSpezialeFDe DonatoGPhysician-initiated prospective Italian Registry of carotid stenting with the C-Guard mesh-stent: the IRON-Guard registry. Rationale and design. J Cardiovasc Surg (Torino). 2015;56:787–791.
80.
NaylorAR. SPACE: not the final frontier. Lancet. 2006;368:1215–1216.
81.
CumminsP, Serruys PW. Peripheral vascular disease: Shaping a new panvascular interventional approach. EuroIntervention. 2015:11:729.
82.
ClevelandTJGainesPAVenablesGS. Carotid artery stenosis: patients should have access to all treatments. BMJ. 2010;340:c1467.