Assessment of Mean Platelet Volume of Pregnant Women with Gestational Diabetes Mellitus and Impaired Glucose Tolerance as a Marker of Future Cardiovascular Disease Risk
Restricted accessResearch articleFirst published online September, 2010
Assessment of Mean Platelet Volume of Pregnant Women with Gestational Diabetes Mellitus and Impaired Glucose Tolerance as a Marker of Future Cardiovascular Disease Risk
Objective To assess the platelet count and mean platelet volume (MPV) of pregnant women with gestational diabetes mellitus (GDM) or gestational impaired glucose tolerance (GIGT) to find out whether GDM and GIGT are risk factors for future development of cardiovascular disease. Study design A 50-g oral glucose load (OGL) was administered to all participants and heamotologic parameters were studied at 24–28 gestational weeks. When plasma glucose ≥ 140 mg/dl (7.8 mmol/L) was measured following the OGL, a 100 g-3-h oral glucose tolerance test was undertaken. Results A significant difference was observed for MPV values between the GDM and normal OGL groups.
Conclusion Presence of a high MPV in GDM could demonstrate an increase in the risk for current and future thrombotic complications.
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