We describe a 32-year-old man with electrocardiographic (ECG) changes consistent with Brugada syndrome and influenza virus infection. The ECG pattern changed after 1 week to one of early repolarization in V1 and V2. This case suggests an association between Brugada syndrome and viral infection.
BrugadaPBrugadaJ: Right bundle branch block, persistent ST segment elevation and sudden cardiac death; a distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol1992; 20: 1391–1396.
2.
MiyazakiTMitamuraHMiyoshiSSoejimaKAizawaYOgawaS: Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol1996; 27: 1061–1070.
3.
RebolloJM GonzalezMadridA HernandezGarciaAde CastroA GarciaMejiasAMoroC: Recurrent ventricular fibrillation during a febrile illness in a patient with the Brugada syndrome (in Spanish, English abstract). Rev Esp Cardiol2000; 53: 755–757.
4.
MoritaHNagaseSKusanoKOheT: Spontaneous T wave alternans and premature ventricular contractions during febrile illness in a patient with Brugada syndrome. J Cardiovasc Electrophysiol2002; 13: 816–818.
Mol'kovaTNBogomolovBPDeviatkinAVSerovaMV: The importance of Holter ECG monitoring in the diagnosis of latent arrhythmias in patients with acute respiratory viral infections (in Russian, English abstract). Ter Arkh1991; 63: 30–32.
7.
DumaineRTowbinJABrugadaPVattaMNesterenkoDVNesterenkoVV: Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent. Circ Res1999; 85: 803–809.
8.
MadleAKratochvilZPolivkovaA: The Brugada syndrome (in Czech, English abstract). Vnitr Lek2002; 48: 255–258.