To synthesise current research exploring the factors and interventions associated with the quality of life of people with dementia.
Background
Dementia is a progressive condition affecting an estimated 40 million people worldwide. The illness has a significant impact on the lives of the persons affected and their loved ones, and may thus impair the quality of life of both. As it progresses, dementia weakens the patients’ ability to express their own views about their quality of life and the factors associated with it.
Design
Scoping review.
Data sources
Electronic database search of MEDLINE, CINAHL, PsycINFO, Joanna Briggs Institute Library, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (DARE), EMBASE, Medic published up to March 2016; and incremental hand search.
Review method: Systematic or other kinds of reviews and single studies were included for the review if they met the inclusion criteria. Results: A total of 20 reviews and 7 primary studies were retained for synthesis. Key findings were abstracted and a themes matrix was generated to identify patterns of meaning. The factors associated with the quality of life of people with dementia were sociodemographic factors, factors related to dementia and social and caring environment. Interventions supporting quality of life focused on the activation of people with dementia. Conclusions: This scoping review identified a large body of knowledge exploring the factors and interventions associated with the quality of life of people with dementia. The interventions were heterogeneous and the sample sizes small, which is why more research is needed.
AblittA.JonesG. V.MuersJ. (2009).
Living with dementia: A systematic review of the influence of relationship factors. Aging & Mental Health,
13(4), 497–511. DOI: 10.1080/13607860902774436.
2.
AgliO.BaillyN.FerrandC. (2015).
Spirituality and religion in older adults with dementia: A systematic review. International Psychogeriatrics,
27(5), 715–725. DOI: 10.1017/S1041610214001665.
3.
AguirreE.WoodsR. T.SpectorA.OrrellM. (2013).
Cognitive stimulation for dementia: A systematic review of the evidence of effectiveness from randomised controlled trials. Ageing Research Reviews,
12(1), 253–262. DOI: 10.1016/j.arr.2012.07.001.
4.
AlviraM. C.RiscoE.CabreraE.FarréM.Rahm HallbergI.BleijlevensM. H., …RightTimePlaceCare Consortium. (2015).
The association between positive-negative reactions of informal caregivers of people with dementia and health outcomes in eight European countries: A cross-sectional study. Journal of Advanced Nursing,
71(6), 1417–1434. DOI: 10.1111/jan.12528.
5.
AnnearM. J.ToyeC.McInerneyF.EcclestonC.TranterB.ElliottK-E.RobinsonA. (2015).
What should we know about dementia in the 21st Century? A Delphi consensus study. BMC Geriatrics,
15, 5. DOI:10.1186/s12877-015-0008-1.
6.
ArchieP.BrueraE.CohenL. (2013).
Music-based interventions in palliative cancer care: A review of quantitative studies and neurobiological literature. Support Care Cancer,
21(9), 2609–2624. DOI:10.1007/s00520.
7.
ArmstrongR.HallB. J.DoyleJ.WatersE. (2011).
Cochrane update: ‘Scoping the scope’ of Cochrane review. Journal of Public Health,
33(1), 147–150. DOI:10.1093/pubmed/fdr015.
8.
BanerjeeS.SamsiK.PetrieC. D.AlvirJ.TregliaM.SchwamE. M.del ValleM. (2009).
What we do know about quality of life in dementia? A review of the emerging evidence on the predictive and explanatory value of disease specific measures of health related quality of life in people with dementia. International Journal of Geriatric Psychiatry,
24(1), 15–24. DOI:10.1002/gps.2090.
9.
BeerC.FlickerL.HornerB.BretlandN.SchererS.LautenschlagerN. T., … AlmeidaO. P. (2010).
Factors associated with self and informant ratings of the quality of life of people with dementia living in care facilities: A cross sectional study. PLoS One,
5(12), e15621. DOI:10.1371/journal.pone.0015621.
10.
BeerensH. C.ZwakhalenS. M. G.VerbeekH.RuwaardD.HamersP. H. (2013).
Factors associated with quality of life of people with dementia in long-term care facilities: A systematic review. International Journal of Nursing Studies,
50(9), 1259–1270. DOI:10.1016/j.ijnurstu.2013.02.005.
11.
BeerensH. C.ZwakhalenS. M.VerbeekH.RuwaardD.AmbergenA. W., … Leino-KilpiH., RightTimePlaceCare Consortium. (2015).
Change in quality of life of people with dementia recently admitted to long-term care facilities. Journal of Advanced Nursing,
71(6), 1435–1447. DOI:10.1111/jan.12570.
12.
BernabeiV.De RonchiD.La FerlaT.MorettiF.TonelliL.FerrariB., … AttiA. R. (2013).
Animal-assisted interventions for elderly patients affected by dementia or psychiatric disorders: A review. Journal of Psychiatric Research,
47(6), 762–773. DOI:0.1016/j.jpsychires.2012.
13.
BowlingA.RoweG.AdamsS.SamsiK.CraneM.JolyL.ManthorpeJ. (2015).
Quality of life in dementia: A systematically conducted narrative review of dementia-specific measurements scales. Aging & Mental Health,
19(1), 13–31. http://dx.doi.org/10.1080/13607863.2014.915923.
14.
BraunV.ClarkeV. (2006).
Using thematic analysis in psychology. Qualitative Research in Psychology,
3(2), 77–101.
15.
BurláC.RegoG.NunesR. (2014).
Alzheimer, dementia and the living will: A proposal. Medicine, Health Care, and Philosophy,
17(3), 389–395. DOI:10.1007/s11019-014-9559-8.
16.
CiprianiG.BorinG. (2015).
Understanding dementia in the sociocultural context: A review. International Journal of Social Psychiatry,
61(2), 198–204. DOI:10.1177/0020764014560357.
17.
CooperC.MukadamN.KatonaC.LyketsosC. G.AmesD.RabinsP., … LivingstonG. (2012).
Systematic review of the effectiveness of non-pharmacological interventions to improve quality of life of people with dementia. International Psychogeriatrics,
24(6), 856–870. DOI:10.1017/S1041610211002614.
18.
CorbettA.StevensJ.AarslandD.DayS.Moniz-CookE.WoodsR., … BallardC. (2012).
Systematic review of services providing information and/or advice to people with dementia and/or their caregivers. International Journal of Geriatric Psychiatry,
27(6), 628–636. DOI:10.1002/gps.2762.
19.
De JongeD. M.JonesA.PhillipsR.ChungM. (2011).
Understanding the essence of home: Older people’s experience of home in Australia. Occupational Therapy International,
18(1), 39–47. DOI:10.1002/oti.312.
20.
FernandezR.ArthurB.FlemingR.PerrinC. (2014).
Effect of doll therapy in managing challenging behaviors in people with dementia: A systematic review. The JBI Database of Systematic Reviews and Implementation Reports,
12(8), 330–363.
21.
FlemingR.KellyF.StillfriedG. (2015). ‘I
want to feel at home’: Establishing what aspects of environmental design are important to people with dementia nearing the end of life. BMC Palliative Care,
14, 26. DOI:10.1186/s12904-015-0026-y.
22.
FungJ. K. K. M.TsangH. W. H.ChungR. C. K. (2012).
A systematic review of the use of aromatherapy in treatment of behavioral problems in dementia. Geriatrics & Gerontology International,
12(3), 372–382. DOI:10.1111/j.1447-0594.2012.00849.x.
23.
GiebelC. M.SutcliffeC.StoltM.KarlssonS.Renom-GuiterasA.SotoM.ChallisD. (2014).
Deterioration of basic activities of daily living and their impact on quality of life across different cognitive stages of dementia: A European study. International Psychogeriatrics,
26(8), 1283–1293. DOI:10.1017/S1041610214000775.
24.
HeggestadA. K.NortvedtP.SlettebøÅ. (2013). ‘
Like a prison without bars’: Dementia and experiences of dignity. Nursing Ethics,
20(8), 881–892. DOI:10.1177/0969733013484484.
25.
HeynP.AbreuB. C.OttenbacherK. J. (2004).
The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis. Archives of Physical Medicine and Rehabilitation,
85(10), 1694–1704. DOI:http://dx.doi.org/10.1016/j.apmr.2004.03.019.
26.
HodgsonN.GitlinL. N.HuangJ. (2014).
The influence of sleep disruption and pain perception on indicators of quality of life in individuals living with dementia at home. Geriatric Nursing,
35(5), 394–398. DOI:10.1016/j.gerinurse.2014.08.005.
27.
HongistoK.HallikainenI.SelanderT.TörmälehtoS.VaatäinenS.MartikainenJ., … KoivistoA. M. (2017, January).
Quality of life in relation to neuropsychiatric symptoms in Alzheimer’s disease: 5-year prospective ALSOVA cohort study. International Journal of Geriatric Psychiatry. DOI:10.1002/gps.4666.
28.
HsiehC.KongJ.KirschI.EdwardsR. R.JensenK. B.KaptchukT. J.GollubR. L. (2014).
Well-loved music robustly relieves pain: A randomized, controlled trial. PLoS One,
9(9), e107390. DOI:10.1371/journal.pone.0107390.
29.
KarttunenK.KarppiP.HiltunenA.VanhanenM.VälimäkiT.MartikainenJ., … PirttilaT.; for the ALSOVA study group. (2011).
Neuropsychiatric symptoms and quality of life in patients with very mild and mild Alzheimer’s disease. International Journal of Geriatric Psychiatry,
26, 473–482. DOI:10.1002/gps.2550.
30.
KhooS. A.ChenT. Y.AngY. H.YapP. (2013).
The impact of neuropsychiatric symptoms on caregiver distress and quality of life in persons with dementia in an Asian tertiary hospital memory clinic. International Psychogeriatrics,
25(12), 1991–1999. DOI:10.1017/S1041610213001518.
31.
LeungP.OrrellM.OrgetaV. (2015).
Social support group interventions in people with dementia and mild cognitive impairment: A systematic review of the literature. International Journal of Geriatric Psychiatry,
30(1), 1–9. DOI:10.1002/gps.4166.
32.
LevacD.ColquhounH.O’BrienK. (2010).
Scoping studies: Advancing the methodology. Implementation Science,
5, 69. Retrieved from www.implementationscience.com/content/5/1/69. DOI:10.1186/1748-5908-5-69.
33.
LivingstonG.KellyL.Lewis-HolmesE.BaioG.MorrisS.PatelN., … CooperC. (2014).
A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia. Health Technology Assessment,
8(39), 1–226, v–vi. DOI: 10.3310/hta18390.
MoosI.BjörnA. (2006).
Use of the life story in the institutional care of people with dementia: A review of intervention studies. Ageing & Society,
26(3), 431–454. DOI:0.1017/S0144686X0600480.
36.
MurrayL. M.BoydS. (2009).
Protecting personhood and achieving quality of life for older adults with dementia in the U.S. health care system. Journal of Aging and Health,
21(2), 350–373. DOI:10.1177/0898264308329017.
NordgrenL.EngstromG. (2014).
Animal-assisted intervention in dementia: Effects on quality of life. Clinical Nursing Research,
23(1), 7–19. DOI:10.1177/1054773813492546.
39.
OlazaránJ.ReisbergB.ClareL.CruzI.Peña-CasanovaJ.del SerT., … MuñizR. (2010).
Nonpharmacological therapies in Alzheimer's disease: A systematic review of efficacy. Dementia and Geriatric Cognitive Disorders,
30(2), 161–178. DOI:10.1159/000316119.
40.
OrgetaV.QaziA.SpectorA. E.OrrellM. (2014).
Psychological treatments for depression and anxiety in dementia and mild cognitive impairment (Review). Cochrane Databases of Systematic Reviews,
22(1), DOI:10.1002/14651858.CD009125.pub2.
41.
O’RourkeH. M.DugglebyW.FraserK. D.JerkeL. (2015).
Factors that affect quality of life from the perspective of people with dementia: A metasynthesis. Journal of the American Geriatrics Society,
63(1), 24–38.
42.
O’RourkeH. M.FraserK. D.DugglebyW. (2015).
Does the quality of life constructs as illustrated in quantitative measurement tools reflect the perspective of people with dementia?Journal of Advanced Nursing,
71(8), 1812–1824. DOI:10.1111/jan.12667.
43.
PearsonA.WiechulaR.LockwoodC. (2007).
A re-consideration of what constitutes “evidence” in the healthcare professions. Nursing Science Quarterly,
20(1), 85–88.
PetersM. D.GodfreyC. M.KhalilH.McInerneyP.ParkerD.SoaresC. B. (2015).
Guidance for conducting systematic scoping reviews. International Journal of Evidence-Based Healthcare,
13(3), 141–146. DOI:10.1097/XEB.0000000000000050.
46.
PhamM. T.R.A.GreigJ. D.SargeantJ. M.PapadopoulosA.McEwenS. A. (2014).
A scoping review of scoping reviews: Advancing the approach and enhancing the consistency. Research Synthesis Methods,
5(4), 371–385. DOI:10.1002/jrsm.1123.
47.
PotterR.EllardD.ReesK.ThorogoodM. (2011).
A systematic review of the effects of physical activity on physical functioning, quality of life and depression in older people with dementia. International Journal of Geriatric Psychiatry,
26(10), 1000–1011. DOI:10.1002/gps.2641.
48.
PrinceM.BryceR.AlbaneseE.WimoA.RibeiroW.FerriC. P. (2013).
The global prevalence of dementia: A systematic review and meta-analysis. Alzheimer’s & Dementia,
9(1), 63–75. DOI:10.1016/j.jalz.2012.11.007.
49.
ReganB.VaranelliL. (2013).
Adjustment, depression, and anxiety in mild cognitive impairment and early dementia: A systematic review of psychological intervention studies. International Psychogeriatrics,
25(12), 1963–1984. DOI:10.1017/S104161021300152X.
50.
RileyR. J.BurgenerS.BuckwalterK. C. (2014).
Anxiety and stigma in dementia: A threat to aging in place. Nursing Clinics of North America,
49(2), 213–231. DOI:10.1016/j.cnur.2014.02.008.
51.
SackettD. L.RosenbergW. M.GrayJ. A.HaynesR. B.RichardsonW. S. (1996).
Evidence based medicine: What it is and what it isn’t. British Medical Journal,
312, 71–72.
52.
SarkamoT.TervaniemiM.LaitinenS.NumminenA.KurkiM.JohnsonJ. K.RantanenP. (2014).
Cognitive, emotional, and social benefits of regular musical activities in early dementia: Randomized controlled study. Gerontologist,
54(4), 634–650. DOI:10.1093/geront/gnt100.
53.
ScheltensP.BlennowK.BretelerM. M.de StrooperB.FrisoniG. B.SallowayS.Van der FlierW. M. (2016).
Alzheimer’s disease. Lancet,
388(10043), 505–517. DOI:10.1016/S0140-6736(15)01124-1.
54.
Schölzel-DorenbosC. J.van der SteenM. J.EngelsL. K.Olde RikkertM. G. (2007).
Assessment of quality of life as outcome in dementia and MCI intervention trials: A systematic review. Alzheimer Disease & Associated Disorders,
21(2), 172–178.
55.
TavaresB. B.MoraesH.Camaz DeslandesA.LaksJ. (2014).
Impact of physical exercise on quality of life of older adults with depression or Alzheimer’s disease: A systematic review. Trends in Psychiatry and Psychotherapy,
36(3), 134–139. doi.org/10.1590/2237-6089-2013-0064.
TrappeH. J. (2012).
Role of music in intensive care medicine. International Journal of Critical Illness and Injury Science,
2(1), 27–31. DOI:10.4103/2229-5151.94893.
59.
TriccoA. C.LillieE.ZarinW.O’BrienK.ColquhounH.KastnerM.StrausS. E. (2016).
A scoping review on the conduct and reporting of scoping reviews. BMC Medical Research Methodology,
16, 15. DOI:10.1186/s12874-016-0116-4.
60.
VasionytéI.MadisonG. (2013).
Musical intervention for patients with dementia: A meta-analysis. Journal of Clinical Nursing,
22(9), 1203–1216. DOI:10.1111/jocn.12166.
WoodsB.AguirreE.SpectorA. E.OrrellM. (2012).
Cognitive stimulation to improve cognitive functioning in people with dementia (Review). Cochrane Database of Systematic Reviews,
15(2). DOI:10.1002/14651858.CD005562.pub2.
