One goal of producing relevant clinical research is to ensure that evidence-based research results are transformed into everyday clinical practice that help clinicians deliver high quality care. It also involves ensuring that the individual patient receives the most effective and least risky treatment, ultimately leading to an optimal treatment outcome both in the short and long term. Some fundamentals of evidence-based dentistry are highlighted with focus on performing orthodontic randomised controlled trials.
AbdulraheemSBondemarkL (2018a) The reporting of blinding in orthodontic randomized controlled trials: where do we stand?European Journal of Orthodontics41: 54–58.
2.
AbdulraheemSBondemarkL (2018b) Hawthorne effect reporting in orthodontic randomized controlled trials: truth or myth? Blessing or curse?European Journal of Orthodontics40: 475–479.
3.
AckermanM (2004) Evidence-based orthodontics for the 21st century. Journal of the American Dental Association135: 162–167.
4.
BondemarkLAbdulraheemS (2018) Intention to treat (ITT) analysis as reported in orthodontic randomized controlled trials: evaluations of methodology and recommendations for the accurate use of ITT analysis and handling dropouts. European Journal of Orthodontics40: 409–413.
5.
BondemarkLRufS (2015) Randomized controlled trial: the gold standard or an unobtainable fallacy. European Journal of Orthodontics37: 457–461.
6.
BraunholtzDAEdwardsSJLilfordRJ (2001) Are randomized clinical trials good for us (in the short term)? Evidence for a “trial effect”. Journal of Clinical Epidemiology54: 217–224.
7.
HeritierSRGebskiVJKeechAC (2003) Inclusion of patients in clinical trial analysis: the intention-to-treat principle. Medical Journal of Australia179: 438–440.
8.
IoannidisJPHaidichABPappaMet al (2001) Comparison of evidence of treatment effects in randomized and nonrandomized studies. Journal of the American Medical Association286: 821–830.
9.
JüniPAltmanDGEggerM (2001) Assessing the quality of controlled clinical trials. British Medical Journal323: 42–46.
10.
LempesiEKoletsiDFlemingPSet al (2014). The reporting quality of randomized controlled trials in orthodontics. Journal of Evidence Based Dentistry and Practice14: 46–52.
11.
PandisN (2011) The evidence pyramid and introduction to randomized controlled trials. American Journal of Orthodontics and Dentofacial Orthopedics140: 446–447.
12.
PandisNShamseerLKokichVGet al (2014) Active implementation strategy of CONSORT adherence by a dental specialty journal improved randomized clinical trial reporting. Journal of Clinical Epidemiology67: 1044–1048.
13.
PandisNWalshTPolychronopoulouAet al (2013) Split-mouth designs in orthodontics: an overview with applications to orthodontic clinical trials. European Journal of Orthodontics35: 783–789.
14.
SackettDLRosenbergWMGrayJAet al (1996). Evidence based medicine: what it is and what it isn’t. British Medical Journal312: 71–72.
15.
SchulzKFAltmanDGMoherD (2010) CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Journal of Clinical Epidemiology3: 834–840.
16.
WertzRT (1995) Intention to treat: once randomized, always analyzed. Clinical Aphasiology23: 57–64.
