Colorectal Cancer Collaborative Group: Adjuvant radiotherapy for rectal cancer: A systematic overview of 8,507 patients from 22 randomised trials. Lancet.2001; 358(9290): 1291–304.
2.
CammaCGiuntaMFioricaFPagliaroLCraxiACottoneMPreoperative radiotherapy for resectable rectal cancer: Meta-analysis. JAMA2000;284(8):1008–1105.
3.
Anonymous: Improved survival with preoperative radiotherapy in resectable rectal cancer. Swedish Rectal Cancer Trial. New Eng J Med1997; 336(14): 980–7.
4.
Medical Research Council Rectal Cancer Working Party- second report: The evaluation of low dose preoperative X-ray therapy in the management of operable rectal cancer; results of a randomly controlled trial. Br J Surg1984; 71: 21–25.
5.
HigginsGAConnJHJordanPHHumphreyEWRoswitBKeehnRJPreoperative radiotherapy for colorectal cancer. Ann Surg1975;181:624–630.
6.
GoldbergPANichollsRJPorterNHLoveSGrimseyJELong-term results of a randomised trial of short-course low-dose adjuvant preoperative radiotherapy for rectal cancer: Reduction in local treatment failure. Eur J Cancer; 30: 1602–1606.
7.
NiebelWSchulzURiedMErhardJBeersiekFBlocherGNierHHalamaHSchererEZellerGFive-year results of prospective randomised study: Experience with combined radiotherapy and surgery for primary rectal carcinoma. Recent Results Cancer Res1988;110:111–113.
8.
DahlOHornAMorildIHalvorsenJFOdlandGReinertsenSReisaeterAKavliHThunoldJLow-dose preoperative radiation postpones recurrences in operable rectal cancer. Results of a randomised multicentre trial in western Norway. Cancer1990; 66: 2286–2294.
9.
HigginsGAHumphreyEWDwightRWRoswitBLeeLEJKeehnRJPreoperative radiation and surgery for cancer of the rectum. Veterans Administration Surgical Oncology Group Trial II. Cancer1986; 58: 352–359.
10.
MarshPJamesRSchofieldLPFAdjuvant pre-operative radiotherapy for locally advanced rectal carcinoma: Results of prospective randomised trial. Dis Colon Rectum1994;37:1205–1214.
11.
KimuraKTuchiyaSMasayukiY: Comparisons of surgical therapy and combined irradiation in rectal cancer: First report, effect of irradiation on the tumour. Jpn J Cancer Chemotherapy1989;16:3161–3172.
12.
GerardABuyseMNordlingerBLoygueJPeneFKempfPBossetJFGignouxMArnaudJPDesaiveCPreoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomised study of the European Organisation for the Research and Treatment of Cancer (EORTC) Ann Surg1988;208:606–614.
13.
Medical Research Council Rectal Cancer Working Party: Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer. Lancet1996; 348: 1605–1610.
14.
CedermarkBJohanssonHRutqvistLEWilkingNThe Stockholm I trial of pre-operative short course radiotherapy in operable rectal cancer: A prospective randomised controlled trial. Cancer1995;75:2269–2275.
15.
Stockholm Colorectal Cancer Study Group: A randomised study on pre-operative radiotherapy in rectal carcinoma. Ann Surg Oncol1996; 3: 423–30.
16.
KapiteijnEMarijnenCANagtegaalIDPutterHSteupWHWiggersTRuttenHJPahlmanLGlimeliusBvan KriekenJHLeerJWvan de VeldeCJDutch Colorectal Cancer Group. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. New Eng J Med2001; 345(9): 638–646.
17.
DahlbergMGlimeliusBPahlmanLImproved survival and reduction in local failure rates after preoperative radiotherapy: Evidence for the generalizability of the results of Swedish Rectal Cancer Trial. Ann Surg1999;229(4):493–497.
18.
DahlbergMGlimeliusBPåhlmanLChanging strategy for rectal cancer is associated with improved outcome. Br J Surg1999;86(3):379–384.
19.
BujkoKNowackiMPBebenekM: Randomized trial comparing high dose per fraction preoperative radiotherapy with immediate surgery versus conventional preoperative radiochemotherapy with delayed surgery for patients with low rectal cancer. Proceedings of the European Association of Coloproctology Ehrlangen2002;2:p25.
20.
ThomasPRLindbladASAdjuvant postoperative radiotherapy and chemotherapy in rectal carcinoma: A review of the Gastrointestinal Tumor Study Group experience. Radiother Oncol1988;13(4):245–252.
21.
MansourELefkopoulouMJohnsonR: A comparison of post-operative chemotherapy, radiotherapy or combination therapy in potentially curable rectal carcinoma: An ECOG study EST4276. Proc ASCO1991; 10: 154 (A484).
22.
FisherBWolmarkNRocketteHRedmondCDeutschMWickerhamDLFisherERCaplanRJonesJLernerH: Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP protocol R-01. Journal of the National Cancer Institute1988;80(1):21–29.
23.
BalslevIPedresenMTeglbjaergPS: Postoperative radiotherapy in Dukes B and C carcinoma of the rectum and rectosigmoid: A randomised multicentre study. Cancer1986; 58:22–28.
24.
ArnaudJPNordlingerBBossetJFBoesGHSahmoudTSchlagPMPeneFRadical surgery and postoperative radiotherapy as combined treatment in rectal cancer. Final results of a phase III study of the European Organisation for Research and Treatment of Cancer. Br J Surg1997; 84: 352–357.
25.
Treurniet-DonkerADvan PuttenWLWereldsmaJCBrugginkEDHoogenraadWJRoukemaJASnijders-KeilholzAMeijerWSMeerwaldtJHWijnmaalenAJPostoperative radiation therapy for rectal cancer. An interim analysis of a prospective randomised multicentre trial in the Netherlands. Cancer1991; 67: 2042–2048.
26.
MarneghanHGrayBNDe ZwartJ: Adjuvant post-operative radiotherapy in rectal cancer: results from the ANZ bowel cancer trial (protocol 8202) Australas Radiol1991; 35: 61–65.
27.
Medical Research Council Rectal Cancer Working Party: Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum. Lancet1996; 348: 1610–1614.
28.
Gastrointestinal Tumor Study Group: Prolongation of the disease-free interval in surgically treated rectal carcinoma. N Eng J Med1985; 312: 1464–1472.
29.
KrookJEMoertelCGGundersonLLWieandHSCollinsRTBeartRWKubistaTPPoonMAMeyersWCMailliardJAEffective surgical adjuvant therapy for high-risk rectal carcinoma. New Eng J Med.1991; 324(11): 709–715.
30.
Gastrointestinal Tumor Study Group: Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. J Clin Oncol1992; 10: 549.
31.
O'ConnellMJMartensonJAWeiandHS: Improving adjuvant therapy for rectal cancer by combining protracted infusion flourouracil with radiation therapy after curative surgery. N Eng J Med1994;331:502.
32.
TveitKMGuldvogIHagenS: Randomised controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Br J Surg1997;84:1130–1135.
33.
WolmarkNWieandHSHyamsDM: Randomised trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R02. J Natl Cancer Inst2000;92:388–396.
34.
TepperJEO'ConnellMJPetroniGR: Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of Intergroup 0114. J Clin Oncol1997;15:2030.
35.
NIH Consensus Conference: Adjuvant therapy for patients with colon and rectal cancer. JAMA1990; 264: 1444–1450.
36.
NeugutAIFleischauerATSundararajanVMitraNHeitjanDFJacobsonJSGrannVUse of adjuvant chemotherapy and radiation therapy for rectal cancer among the elderly: A population-based study. J Clin Oncol2002;20(11):2643–2650.
37.
PahlmanLGlimeliusBPre-operative or post-operative radiotherapy in rectal and recto-sigmoid carcinoma — Report from a randomised multi-centre trial. Ann Surg1990;211:187–195.
38.
HealdRJMoranBJRyallRDHSextonRMacFarlaneJKRectal cancer. The Basingstoke experience of total mesorectal excision). Arch Surg1998; 133: 894–898.
39.
MartlingALHolmT: Effect of a surgical training programme on the outcome of rectal cancer in the County of Stockholm. Lancet2000;356:93–96.
40.
WibeARendedalPRSvenssonENorsteinJEideTJMyrvoldHESoreideOPrognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg2002;89(3):327.
41.
AdamIJMohamdeeMOMartinIG: Role of circumferential resection margin involvement in the local recurrence of rectal cancer. Lancet1994;344:707–711.
42.
BirbeckKFMacKlinCPTiffinNJParsonsWDixonMFMapstoneNPAbbottCRScottNFinanPJJohnstonDQuirkePRates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg2002;235(4):449–457.
43.
MarijnenCAMNagtegaalIDKranenbargEKHermansJ: No downstaging after short-term preoperative radiotherapy in rectal cancer patients. J Clin Oncol2001;19(7):1976–1984.
44.
NagtegaalIDvan de VeldeCJHvan der WorpEKapiteijnEPhilQuirke and J Han JM van Krieken J Han JM: Macroscopic evaluation of rectal cancer resection specimen: Clinical significance of the pathologist in quality control. J Clin Oncol2002;20(7):1729–1734.
45.
MarijnenCAMLeerJ-WHPutterHKapiteijnE: Interval between preoperative radiotherapy and surgery influences postoperative mortality in rectal cancer patients: The sooner the better. In: Radiotherapy in Rectal Cancer. Marijnen C, Leiden200255–68.
46.
NagtegaalIDMarijnenCAMKranenbargEK: Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma. Am J Surg Pathol2002;26:350–357.
47.
Glynne-JonesRSebag-MontefioreDRectal Cancer: What can we learn from the Dutch TME Study? How will this study impact on current practice in the U. K? Clin Oncol2002; 14(2): 170–173.
BotterillIDBluntDMQuirkePSebag-MontefioreDSagarPMFinanPJChalmersAGEvaluation of the role of pre-operative magnetic resonance imaging in the management of rectal cancer. Colorectal Disease2001;3(5):295–303.
50.
BlomqvistLMacHadoMRubioCGabrielssonNGranqvistSGoldmanSHolmTRectal tumour staging: MR imaging using pelvic phased-array and endorectal coils vs endoscopic ultrasonography. Europ Radiol2000;10(4):653–660.
51.
BrownGRichardsCJNewcombeRG: Rectal carcinoma: Thin-section MR imaging for staging in 28 patients. Radiology1999;211(1):215–222.
52.
BissettIPFernandoCCHoughDM: Identification of the fascia propria by magnetic resonance imaging and its relevance to preoperative assessment of rectal cancer. Dis Colon Rectum2001;44:259–265.
53.
Beets-TanRGHBeetsGLVliegenRFA: Accuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery. Lancet2001;357:497–504.
54.
FrykholmGJPahlmanLGlimeliusBCombined chemo and radiotherapy versus radiotherapy alone in the treatment of primary, non-resectable adenocarcinoma of the rectum. Int Rad Oncol Biol Phys2001;50:433–440.
55.
RichTASkibberJMAjaniJABuchholzDJClearyKRDubrowRA: Preoperative infusional chemoradiation therapy for stage T3 rectal cancer. Int J Rad Oncol Biol Phys1995; 32:1025–1029.
56.
MinskyBCohenAEnkerWKelsenDKemenyNIlsonDGuillemJSaltzLFrankelJContiJPreoperative 5-fluorouracil, low-dose leucovorin, and concurrent radiation therapy for rectal cancer. Cancer1994;73:273–278.
57.
MinskyBDKerneyNCohenAM: Pre-operative high dose leucovorin/5-fluorouracil and radiation therapy for unresectable rectal cancer. Cancer1991;67:2859–2866.
58.
BossetJFPavyJJHamersHPHoriotJCFabriMCRougierPEschwegeFSchraubSDetermination of the optimal dose of 5-fluoruracil when combined with low dose D L-leucovorin and irradiation in rectal cancer: Results of three consecutive phase II studies. EORTC Radiotherapy Group. European Journal of Cancer1993; 29A: 1406–1410.
59.
Glynne-JonesRSebag-MontefioreDChemoradiation schedules — What radiotherapy? Eur J Cancer2002;38(2):258–269.
60.
JanjanNAAbbruzzeseJPazdurRKhooVSClearyKDubrowRAjaniJRichTAGoswitzMSEvettsPAAllenPKLynchPMSkibberJMPrognostic implications of response to preoperative infusional chemoradiation in locally advanced rectal cancer. Radiother Oncol1999;51(2):153–160.
61.
BouzoureneHBosmanFTSeelentagWMatterMCouckePImportance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy. Cancer2002;94(4):1121–1130.
62.
DworakOKeilholzLHoffmannAPathological features of rectal cancer after preoperative radiochemotherapy. Int J Color Dis1997;12(1):19–23.
63.
FrykholmGJSintornKMonteliusA: Acute lumbosacral plexopathy after preoperative radiotherapy in rectal cancer. Radiother Oncol1996;38:121.
64.
HolmTSignomklaoTRutqvistL-ECedermarkBAdjuvant preoperative radiotherapy in patients with rectal carcinoma: Adverse effects during long term follow-up of two randomized trials. Cancer1996;78(5):968–976.
65.
KollmorgenCFMeagherAPPembertonJH: The long-term effect of adjuvant postoperative chemoradiotherapy for rectal cancer on bowel function. Ann Surg1994;220:76.
66.
DahlbergMGlimeliusBGrafWPahlmanLPreoperative irradiation affects functional results after surgery for rectal cancer. Dis Colon Rectum1998;41:543.