Airborne Beta-1,3-Glucan May Be Related to Symptoms in Sick Buildings

Abstract

Airborne endotoxin and β-1,3-glucan were measured in buildings in which complaints of eye and airway irritation as well as fatigue and skin symptoms had been numerous. The presence of symptoms was evaluated using question naires. Dose-response relationships were found between levels of β-1,3-glucan and eye and throat irritation, dry cough and itching skin. The data suggest that β-1,3-glucan may be responsible for symptoms seen among persons in sick buildings.

Keywords

β-1,3-Glucan Airborne endotoxin Sick building

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