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Abstract

Introduction

Young people are at risk of developing mental health disorders. Depression, anxiety, and behavioral problems are among the primary causes of illness and impairment among teenagers. Suicide is the fourth highest cause of mortality in those aged 15 to 29. This study aimed to assess the determinants of mental health among children in Ethiopia.

Methods

Online databases were searched from inception until March 2023. Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 was used in this review. Subgroup analysis, I² test, funnel plot, and Egger’s test were performed. Pooled odds ratios (OR) were calculated.

Result

Fourteen studies were included in the meta-analysis. The pooled prevalence of mental illnesses among Ethiopian children was 24.68% (95% CI: 19.99%–32.38%). Having previous child abuse history (OR: 5.65; 95% CI: 4.32-7.39), poor socio-economic status (OR: 1.94; 95% CI: 1.24-3.04), urban residence (OR: 1.93; 95% CI:1.39-2.67), and being male (OR: 1.65; 95% CI: 1.15-2.38) were determinants of childhood mental illness in Ethiopia.

Conclusion

and Recommendations: Mental disorders are highly prevalent in children with a history of child abuse, and a strong legislative body must be established to prosecute child abusers. Interventions that focus on gender equality in education and the creation of a safe environment for poor urban children are suggested.

Keywords

Children mental illness mental health depression anxiety mental disorder

Introduction

A mental disorder or mental health condition is described as a disturbance in psychological, biological, or developmental processes that underpin mental and behavioral functioning (World Health Organiation, 1992, World Health Organiation, 2022; World Health Organiation). Disturbances are typically associated with difficulties or impairments in personal, familial, social, educational, occupational, and other critical aspects of functioning (World Health Organiation, 2022). Broadly, mental disorders include psychosocial disabilities and other mental states associated with considerable distress, functional impairment, and the risk of self-harm (World Health Organiation). Mental health problems pose a risk for other diseases and lead to both unintentional and purposeful damage (Organization(PAHO) & P.A.H).

Childhood and adolescence are critical stages of physical and mental development. The development of good mental health is critical for good overall health and wellbeing throughout life. Mental diseases in children are characterized by substantial changes in how they normally develop, act, or manage their emotions, resulting in dissatisfaction and difficulties in their daily lives. Many children have occasional concerns, worries, and violent behaviors that cause anxiety (Lebrun-Harris & et al., 2022).

Worldwide, mental health problems affect over 15% of young people aged 10–19 years, accounting for 13% of the global disease burden in this age group (World Health Organization, 2021). From 2016 to 2019, the rate of emergency department (ED) visits in the United States of America (USA) with a primary mental health diagnosis increased only among those aged 0–17 years, rising from 784.1 to 869.3 per 100,000. This declined marginally in 2019, but in 2018 it was 976.8 per 100,000 people, a 25% increase from 2016 (Office of the Surgeon G).

More than 20% of children aged 2–8 years in the United States (17.4%) have documented mental, behavioral, or developmental disabilities (Cree et al., 2018). Over 15% of teenagers aged 12–17 years had major depressive episodes, 37% had chronic feelings of despair or hopelessness, and nearly 20% seriously considered suicide (Bitsko et al., 2022).

Boys were more likely than girls to have mental, behavioral, or developmental impairments between the ages of 2 and 8 years. However, a review in the Middle East and USA revealed that depression in teens is a difficult challenge among adolescent girls because it is caused by both environmental and hereditary factors (Cree et al., 2018; Beirão et al., 2020). Furthermore, more than one-fifth (22%) of the children living in poverty had mental, behavioral, or developmental impairments. Age and socioeconomic status influence the likelihood of children receiving therapy for anxiety, depression, or behavioral issues (Ghandour et al., 2019).

Deaths due to suicide among black children and adolescents in the USA have increased considerably in recent years. Suicide deaths among black youths climbed from 2.6 per 100,000 in 2017 to 4.8 per 100,000 in 2018. Compared to their white counterparts, black males aged 5–11 years are more likely to commit suicide (Ring-the-Alarm-TASKFORCE-REPORT.pdf).

At least one in every seven children in sub-Saharan Africa suffers severe psychological distress. In Africa, millions of young people have been exposed to situations that most adults would find difficult to deal with, frequently dealing with psychological consequences without support (Anonymous).

In sub-Saharan Africa, depression was reported to be prevalent in 27% of the population aged 10–19 years, anxiety disorders in 30%, emotional and behavioral difficulties in 41%, and suicidal ideation in 12%. According to one study, the prevalence of post-traumatic stress disorder (PTSD) was 21% (Jörns-Presentati et al., 2021).

The prevalence of mental disorders in eastern Mediterranean children is estimated to range between 12 and 25% (World Health Organization, 2020). According to the World Health Organization, the age-standardized suicide rate in Ethiopia was 11.4% in 2016, with males having a higher rate (18.7) than females (4.7) (Meshesha & Johnson, 2020).

Attention-deficit/hyperactivity disorder (ADHD) (Lian et al., 2013), fears or anxieties (Sacco, 2022), and behavioral disorders (Tadesse, 1999a) are some of the most prevalent mental diseases in the Ambo region of Ethiopia, and can be diagnosed in children.

The Federal Ministry of Health (FMOH) identified more specific categories of mental health problems among children and adolescents on its website in 2019 as part of a mental health forum, namely ADHD (Greene et al., 2021), oppositional defiant disorders/conduct disorders (Isaksson et al., 2017), anxiety disorders (Lippman, 1976; Ayano, 2021), mood disorders (Ashenafi et al., 2001), elimination disorders (Adewuya et al., 2014), and autism spectrum disorders (Zeleke et al., 2021). The research also revealed a prevalence of "common mental health disorders” (depression, anxiety, and psychological discomfort) ranging from 21.56% to 27.9% (Barsisa et al., 2021).

Although various efforts have been made to address the negative effects of mental disorders and reduce the prevalence of mental illnesses, challenges remain. Emerging rifts, political instabilities, and financial crises are at the forefront of this trend. Although effective prevention and treatment options exist, most children with mental disorders do not receive treatment. Furthermore, many experience stigma, discrimination, and human rights violations (World Health Organiation, 2015).

Identifying factors that contribute to mental disorders can help reduce their prevalence and promote early action. This study aimed to estimate the pooled factors associated with mental disorders among Ethiopian children.

Methods

Exploration approach for primary studies

We searched ScienceDirect, PubMed, the Cochrane Library, and Google scholar for articles. The following keywords on the condition, context, and population were combined using Boolean words for searching: (Mental Disorder) OR (Psychiatric Illness) OR (Psychiatric Illnesses) OR (Psychiatric Diseases) OR (Psychiatric Disease)) OR (Mental Illness) OR (Illness, Mental) OR (Mental Illnesses) OR (Psychiatric Disorders)) OR (Psychiatric Disorder) OR (Behavior Disorders) OR (Diagnosis, Psychiatric)) OR (Psychiatric Diagnosis) OR (Mental Disorders, Severe) OR (Mental Disorder, Severe)) OR (Severe Mental Disorder) OR (Severe Mental Disorders) OR (Mental patients) OR (Mental Disorder[MeSH Terms]) OR (Psychiatric Illness[MeSH Terms]) OR (Psychiatric Illnesses[MeSH Terms]) OR (Psychiatric Diseases[MeSH Terms]) OR (Psychiatric Disease[MeSH Terms]) OR (Mental Illness[MeSH Terms]) OR (Illness, Mental[MeSH Terms]) OR (Mental Illnesses[MeSH Terms) OR (Psychiatric Disorders[MeSH Terms]) OR (Psychiatric Disorder[MeSH Terms) OR (Behavior Disorders[MeSH Terms]) OR (Diagnosis, Psychiatric[MeSH Terms) OR (Psychiatric Diagnosis[MeSH Terms]) OR (Mental Disorders, Severe[MeSH Terms) OR (Mental Disorder, Severe[MeSH Terms]) OR (Severe Mental Disorder[MeSH Terms) OR (Severe Mental Disorders[MeSH Terms]) AND (Ethiopia) OR (Federal republic of Ethiopia) OR (Ethiopia[MeSH Terms]) AND (Children) OR (Child[MeSH Terms) OR (children[MeSH Terms]) OR (Boys[MeSH Terms]) OR (Girls[MeSH Terms).

Eligibility criteria

Inclusion criteria

This systematic review and meta-analysis included both published and unpublished studies in English from the beginning of data inception until February 2023 that reported any type of mental illness in children in Ethiopia. Cross-sectional, case-control, retrospective, and prospective cohort studies have also been included. Only Ethiopian studies that reported any mental disease or at least one adjustment-related factor were considered.

Exclusion criteria

After submitting requests to the respective corresponding authors of the studies, articles that were not fully accessible were excluded. Reports and reviews were excluded from this study.

Outcome measurements

The primary outcome of this study was to assess prevalence, and the secondary outcome was to identify the factors linked to children’s mental health. We estimated the odds ratio (OR) from the primary studies using two-by-two tables for key variables.

Data extraction

The relevant data were extracted using a data extraction format created independently using Microsoft Excel. The data extraction format for the primary outcome included the first author, region (according to the Ethiopian political administration), study period, publication year, study design, sample size, response rate, and prevalence of mental disorders among children.

A data extraction format for the secondary outcome (related factors) was established for each item (age, domicile, parental income, marital status, parental educational status, child abuse history, living situation, and family size). To calculate the odds ratio (OR), we gathered the data for each factor in the form of two tables. Any disagreements between the researchers (KWM, SDH, and BM) during the extractions were resolved by consulting with MA, BM, and ET.

Operational definitions

Children

Young people under 18 years

ADHD

Continuing pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development (Sathiyasusuman, 2011)

Depression

Mood illness characterized by a persistent sense of sadness and loss of interest (Nyundo et al., 2020).

Emotional Behavioral Problem (EBP)

An emotional condition characterized by excesses, deficits, or disturbances in behavior (Tadesse et al., 2012).

Quality assessment

We used the Newcastle-Ottawa Scale to assess the quality of the included cross-sectional studies (Peterson et al., 2011). The tool consists of three main sections: 1) assessing the methodological quality of the studies, 2) evaluating the comparability of the studies, and 3) measuring the outcome and statistical analysis qualities of the original studies.

Statistical analysis

The data were extracted using Microsoft Excel^™, and the data were exported from Microsoft Excel to Stata^™ Version 14.0 (software) for management and further analysis. The data are presented using text, tables, graphs, and forest plots. We calculated the standard error of the prevalence for each original article.

The heterogeneity between the prevalence of the previous studies was checked using the I² test together with p-values. Owing to the presence of significant heterogeneity between previous studies (I² = 96.5%, p < .001), a random-effects meta-regression analysis model was used to estimate the pooled prevalence of children’s mental illnesses in Ethiopia. Moreover, the univariate meta-regression model considered the publication year and sample size of the studies to identify possible sources of heterogeneity. However, these differences were not statistically significant. Potential publication bias was assessed using Egger’s correlation and Begg’s regression intercept tests at 5% significance level. The results of these tests revealed significant publication bias (p > .001 in Egger’s test). To minimize the heterogeneity of the original studies, a subgroup analysis was performed based on the publication year and study setup. Sensitivity analysis and meta-trim-and-fill analysis were performed to determine the impact of a single study on the overall meta-analysis estimate and to remove extremely small studies from one side of the funnel plot. The relationship between mental illness and its associated factors was determined using pooled odds ratios (OR with 95% confidence intervals (CI) for each factor.

Ethics approval

Not applicable.

Results

Exploration of original articles

A total of 1,267 studies were obtained from PubMed, Cochrane, Science Direct, and Google Scholar. Owing to duplication, 240 articles were removed from the list of articles retrieved. Of the remaining 1,027 articles, 600 were excluded after reviewing the titles. Next, 220 articles were excluded because they had multiple outcome variables. After reviewing the remaining 207 abstracts, 194 were eliminated, of which 16 were eliminated due to differences in outcome variables. One new article conducted in January 2023 were added. Finally, 14 articles were retained (Alenko et al., 2020; Aliye et al., 2023; Ashenafi et al., 2000; Fekadu et al., 2006; Gebeyehu et al., 2019; Girma et al., 2021; Jebena et al., 2016; Lola & Belete, 2019; Mulatu, 1995; Mulu et al., 2022; Nyundo et al., 2020; Shiferaw et al., 2018; Tadesse et al., 1999b, 2012) for final qualitative analysis, as shown in the PRISMA flowchart (Figure 1).

Figure 1.

PRISMA flow chart of studies on mental illness among children in Ethiopia.

Characteristics of original studies

Thirty-six percent of the studies were conducted between 2020-2023 (Nyundo et al., 2020; Alati et al., 2023; Alenko et al., 2020; Mulatu, 1995). In contrast, 21% of the articles were published between 2018 and 2019 (Lola & Belete, 2019; Shiferaw et al., 2018; Gebeyehu et al., 2019). Another 36% of studies were conducted between 2000-2016 (Tadesse et al., 2012; Alati et al., 2023; Ashenafi et al., 2000; Fekadu et al., 2006). Two studies were conducted between 1995 and 1999 (Mulatu, 1995; Tadesse, 1999a). Around 57% of studies were conducted in the Oromia region in Ambo Town, Jima, Illibuabur, and Harar (Nyundo et al., 2020; Tadesse et al., 2012; Lola & Belete, 2019; Shiferaw et al., 2018; Alati et al., 2023; Alenko et al., 2020; Girma, 2021; Jebena, 2016). Two studies (14%) were conducted in the Amhara (Gebeyehu et al., 2019; Mulu et al., 2022) and Addis Ababa (Tadesse et al., 2012; Fekadu et al., 2006). One study was conducted in Southern Ethiopia (Ashenafi et al., 2000). The pooled prevalence of any type of mental illness among children in Ethiopia was estimated using 10,506 participants. The response rates in the included primary studies ranged from 95.1% in Guji (Oromia region) (Lola & Belete, 2019)to 100% in Addis Ababa (Lola & Belete, 2019), Butajira (Ashenafi et al., 2000), Jima (Alenko et al., 2020) and Ambo (Tadesse et al., 1999b) (Table 1).

Table 1.

Characteristics of Included studies in meta-analysis of Determinants for mental Illness in Ethiopian children.

Author	Pub. Year	Journal	Country	Region	Study area	Sample size	Study population	Design	Prevalence (%)	Response rate	Types of mental disorder
Lola et al	2019	Hindawi	Ethiopia	Oromia	Guji	1302	6–17 years	Cross- sectional	7.3	95.1	ADH
Shiferaw et al	2018	Hindawi	Ethiopia	Oromia	Illubabur	220	11–17 years	Cross- sectional	24.1	98.2	Depression
Tadesse et al	2012	Taylor and Francis	Ethiopia	Addis Ababa	Addis Ababa	318	6–14 years	Cross- sectional	39.3	100	EBP
Gebeyaw et al	2019	BMC	Ethiopia	Amhara	Northwest	411	13–17 years	Cross-sectional	43.6	97.2	EBP
Alati et al	2023	BMC	Ethiopia	Oromia	Jima	520	10–14 years	Cross- sectional	9.9	96.9	ADH
Ashenafi et al	2000	East Africa Medical Journal	Ethiopia	South	Butajira	1477	10–14 years	Cross- sectional	3.5	100	ADH
Alenko et al	2020	Gen. Psychiatry	Ethiopia	Oromia	Jima	734	10–17 years	Cross- sectional	19.9	100	EBP
Girma et al	2021	PLOS	Ethiopia	Oromia	Jima	546	5–15 years	Cross- sectional	28	97.3	Depression
Mulatu et al	1995	JAM	Ethiopia	Ethiopia	Ethiopia	611	10–17 years	RCT	46.62	100	Depression
Fekadu et al	2006	J Child Psychiatry	Ethiopia	Addis Ababa	Addis Ababa	1000	15–17 years	Cross- sectional	16.5	100	EBP
Jebena et al	2016	PLOS	Ethiopia	Oromia	Jima	1521	12–17 years	Cross- sectional	30.8	100	Depression
Nuyando et al	2020	PLOS	Ethiopia	Oromia	Harar	1059	6–17 years	Cross- sectional	46.5	100	Depression
Tadesse et al	1999	Acta Psychiatry	Ethiopia	Oromia	Ambo	422	5–17 years	Cross- sectional	17.7	100	EBP
Mulu et al	2022	Ethiopia health Science	Ethiopia	Amhara	All zones	365	6–17 years	Cross-sectional	13	97.3	ADH

Data management and analysis

Attention Deficit Hyperactivity (ADH) among children in Ethiopia

There was evidence of heterogeneity (I² = 94.4%, p ≤ .001) in the included studies. Therefore, we used a random-effects meta-analysis to estimate the pooled prevalence of ADH in Ethiopian children. The pooled prevalence of ADH in Ethiopian children was 8.16% (95% CI:4.51-11.82) (Figure 2(a)).

Figure 2.

Pooled prevalence of ADH, EBP, depression, and any mental illness among children in Ethiopia.

Emotional and behavioral problems (EBP) among children in Ethiopia

Heterogeneity was observed (I² = 97.3%, p < .001) in the included studies. Therefore, we used a random-effects meta-analysis model to estimate the pooled prevalence of EBP in Ethiopian children. As a result, the pooled prevalence of EBP in Ethiopian children was 27.1% (95% CI:17.78-36.60) (Figure 2(b)).

Depression among children in Ethiopia

Heterogeneity was observed (I² = 96.9%, p < .001) in the included studies. Therefore, we used a random-effects meta-analysis model to estimate the pooled prevalence of depression among Ethiopian children. The pooled prevalence of depression among Ethiopian children was 35.30% (95% CI:26.56-44.04) (Figure 2(c)).

Any mental illness among children in Ethiopia

There was evidence of heterogeneity (I² = 99.3%, p ≤ .001) in the included studies. Therefore, we used a random-effects meta-analysis model to estimate the pooled prevalence of mental illnesses among Ethiopian children. The pooled prevalence of mental illness in Ethiopian children was 24.68% (95% CI:19.99-32.38) (Figure 2(d)).

Potential sources of heterogeneity were investigated using a univariate regression model for factors associated with heterogeneity, such as sample size variation and publication year, but none were found to be statistically significant (Table 2).

Table 2.

Factors Related to Heterogenicity in studies of any mental Illness Among Ethiopian children (Univariate Meta Regression Model).

Variables	Coefficient	p-value
Sample size	−.008	.995
Publication year	31.20	.978

Funnel plots and Egger tests were used to assess publication bias. Visual inspection revealed slight asymmetry, indicating publication bias (Figure 3), while the p-value of Egger’s tests was .001, which suggests publication bias.

Figure 3.

Funnel plot tests for publication bias of studies of any mental illness among Ethiopian children.

Meta trim and fill analysis

Trim-and-fill analysis were used to remove extremely small studies from one side of the funnel plot (Figure 4).

Figure 4.

Meta trim and fill analysis of studies of any mental illness among Ethiopian children.

Subgroup analysis

Publication year and study region were used for the subgroup analysis. The pooled prevalence of any mental illness of Ethiopian children was higher in studies published after 2016 at 23.98% (95% CI 13.35-34.61). The pooled prevalence of mental illness among Ethiopian children also varies by region. As a result, studies conducted in Addis Ababa revealed a higher pooled prevalence of any mental illness (27.77%, 95% CI 5.42-50.11) than studies conducted in the Oromia region (Table 3).

Table 3.

Subgroup Analysis of mental Illness in Ethiopian children and its Determinants.

Variables	Characteristics	Number of studies	Prevalence (%)	95%CI	Heterogeneity
Variables	Characteristics	Number of studies	Prevalence (%)	95%CI	I²(%), p value
Publication year	≥2016	8	23.98	13.35-34.61	99.1%, p < .00
Publication year	<2016	6	25.65	11.93-39.38	99.5%, p < .00
Study regions	Oromia	8	23	13.11-32.90	99.1%, p < .00
	Addis Ababa	2	27.77	5.42-50.11	98.3%, p < .00
	Amhara	2	28.25	−1.73-58.24	99%, p < .00

Sensitivity analysis

Sensitivity analysis was used to show how a single study affected the overall meta-analysis. Thus, sensitivity analysis revealed that our findings were strong and did not rely on a single study (Figure 5).

Figure 5.

Sensitivity analysis of studies of any mental illness among Ethiopian children.

Associated factors of any mental illness among children in Ethiopia

Our research identified four predictive factors associated with mental illness in Ethiopian children:

Sexual abuse history

Four studies (Shiferaw et al., 2018; Mulu et al., 2022; Alenko et al., 2020; Fekadu et al., 2006) with 2,319 respondents were included to assess the association between childhood sexual abuse and mental illness among children in Ethiopia. The results showed that children who experienced abuse were 5.65 times more likely (OR:5.65; 95% CI:4.32-7.39) to experience mental illness than their counterparts (Figure 6(a)).

Figure 6.

Associated factors of any mental illness among Ethiopian children.

Parental socio-economic status

Two studies (Lola & Belete, 2019; Jebena et al., 2016) with 2,823 respondents were included to assess the association between socio-economic status and mental illness among children in Ethiopia. The results showed that children from low socio-economic status were 1.94 times more likely (OR:1.94; 95% CI:1.24-3.04) to experience any mental illness than children come from high socio-economic status (Figure 6(b)).

Resident and any mental illness among children

Two studies (Ashenafi et al., 2000; Jebena et al., 2016) with 2,998 respondents were included to assess the association between area of residence and mental illness among children in Ethiopia. The results showed that children who reside in urban areas were 1.93 time more likely (OR:1.93; 95% CI:1.39-2.67) to experience mental illness than children who resides in rural areas (Figure 6(c)).

Gender and any mental illness among children

Two studies (Lola & Belete, 2019; Shiferaw et al., 2018) with 1,522 respondents were conducted to assess the association between gender and mental illness among children in Ethiopia. Male children were 1.65 times more likely (OR:1.65; 95% CI:1.15-2.38) to experience any mental illness than female children (Figure 6(d)).

Discussion

The overall prevalence of mental illness in children was 26.25% (17.56–34.93%). This finding was higher than that of systematic reviews conducted in Europe and 11 high-income countries, which found that the pooled prevalence of any mental disorder was 15.5% (95% CI 9.4–24.5%, I² = 99.8%) and 12.7% (95% CI 10.1%–15.9%, I² = 99.1%), respectively (Sacco, 2022; Jenny Lou, 2022). This disparity may be related to socio-demographic differences and standard living conditions, as Europe and other industrialized countries have different childcare systems than Ethiopia.

However, the prevalence in this study was lower than that of a systematic review conducted in France, which reported a pooled prevalence of mental illness among children of 49% (43%–54%) (Bronsard et al., 2016). This discrepancy may be due to socio-demographic differences and the influence of Coronavirus Disease 2019 (COVID-19) in European countries Since this study included all researches conducted at and before 2023.

In this study, the pooled prevalence of ADH among children was 8.16% (95% CI: 4.51%–11.82%). This result was slightly higher than that of systematic reviews conducted in China, Europe, and other high-income nations, which found that the national-pooled prevalence of ADHD in children was 5.7% (95% CI: 4.9%–6.6%), 2.9% (95% CI: 1.2%–6.9%), and 3.7% (95% CI: 2.3%–5.7%), respectively (Lian et al., 2013; Sacco, 2022; Jenny Lou, 2022). In addition to socio-demographic variables and sample size discrepancies, this gap may be attributed to differences in research design and ADH evaluation techniques

In this review, the pooled prevalence of EBPs was found to be 27.19% (95% CI: 17.76%–36.60%). This is greater than the prevalence of EBPs reported by teachers in Nepal (15.4%), whereas the previously reported parental rate was 19.1% (Mahat et al., 2021). This disparity may be caused by socio-economic differences and discrepancies in the techniques used to assess EBP. In comparison, the prevalence of EBP was found to be 41.4% in a study conducted in northern Uganda (Jörns-Presentati et al., 2021). This disparity may be attributed to socio-demographic differences.

The pooled prevalence of depression was 35.30% (95% CI: 26.57%–44.04%). This finding was higher than studies conducted in South Africa and on child welfare in industrialized countries, Ireland, and Europe, which indicated a lifetime prevalence of depression among children of 2.6%, 18%, 20.8%, and 1.7%, respectively (Jörns-Presentati et al., 2021; Sacco, 2022; Bronsard et al., 2016; Lynch et al., 2022). This disparity could be attributed to socio-demographic differences and standard living circumstances.

Male sex has been linked to mental disorders in Ethiopian children. In keeping with this finding, systematic studies conducted in the Middle East, United States, Belgium, and United Kingdom indicated that boys are more likely to suffer from mental illness (Dimitry, 2012; Martin & Hadwin, 2022; Van Droogenbroeck et al., 2018; Yoon, 2022). This might be because boys have a greater tendency to struggle with anger, engage in risky behaviors, and attempt suicide than girls. Teenage girls are more likely to want to express their emotions by crying or interacting with their peers, whereas teenage boys have more difficulty articulating their sentiments and prefer to separate themselves from others when they worry too much(Otten et al., 2021).

Children from families with lower socio-economic status were more likely to suffer from mental illness than those from families with higher status. Similarly, a study conducted in Norway (Kinge et al., 2021), a systematic review conducted in low- and middle-income countries (Ribeiro et al., 2023), and a systematic review conducted during the COVID-19 pandemic (Stracke et al., 2023) all found that children’s mental health was related to their parents' socio-economic status. This could be because a low socio-economic status causes social stress and stigma, both of which contribute to poor mental health.

This systematic review and meta-analysis also revealed that children living in cities were more likely to suffer from mental illness than those living in rural areas. Studies undertaken in Denmark (Engemann et al., 2019), Berlin (Gruebner et al., 2017), and Brussels (Pelgrims et al., 2021) also revealed that living in cities was connected with mental disorders in children. This could be because urban settings are associated with several risk factors for mental illness such as noise, environmental pollutants, criminal activity, and hazardous substances.

Children who had previously been abused were more likely to develop mental illnesses than their peers. Studies conducted in Canada (Su et al., 2022), the USA (Lippard & Nemeroff, 2020), China (Zhao, 2019), and Korea (Ha & Kim, 2023) also found that survivors of child abuse were more likely to experience mental illnesses. Abuse can cause survivors to experience feelings of loneliness, anxiety, and insecurity, which can lead to lasting psychological consequences such as academic difficulties, a lack of self-worth, sadness, and trouble in forming and sustaining relationships (Khoury et al., 2010).

Limitations of the study

This systematic review and meta-analysis had some limitations. Our study only included cross-sectional studies that is impossible to establish a cause-and-effect relationship or to analyze behaviors across time. It is advised that cohort and case–control studies be done.

Conclusion and recommendations

There was a high frequency of mental disorders among children. In Ethiopia, a history of child abuse, low socio-economic status, urban residence, and male sex were all associated with childhood mental illness. Interventions focusing on gender equality education, supporting children from low socio-economic backgrounds, and creating a healthy atmosphere for children living in urban areas are recommended. Additionally, the government might support organizations that help children who have been victims of child abuse, and a strong legislative body should be established to punish child abuse.

Footnotes

Acknowledgments

We would like to thank all the authors of the primary studies analyzed in this research.

Author Contributions

Conceptualization: Kalkidan Worku, Samuel Derbie Habtegiorgis

Data curation: Samuel Derbie Habtegiorgis, Kalkidan Worku, Eniyew Tegegne, Birhanu Melaku

Formal analysis: Samuel Derbie Habtegiorgis, Menichil Amsalu, Kalkidan Worku

Investigation: Samuel Derbie Habtegiorgis, Kalkidan Worku, Eniyew Tegegne, Birhanu Melaku

Methodology: Samuel Derbie Habtegiorgis, Kalkidan Worku, Menichil Amsalu

Project administration: Kalkidan Worku, Eniyew Tegegne.

Resources: Eniyew Tegegne, Menichil Amsalu

Software: Kalkidan Worku, Samuel Derbie Habtegiorgis

Supervision: Samuel Derbie Habtegiorgis, Kalkidan Worku, Menichil Amsalu

Validation: Samuel Derbie Habtegiorgis, Eniyew Tegegne

Visualization: Samuel Derbie Habtegiorgis, Eniyew Tegegne, Menichil Amsalu

Writing – original draft: Samuel Derbie Habtegiorgis, Kalkidan Worku, Birhanu Melaku

Writing – review & editing: Samuel Derbie Habtegiorgis, Kalkidan Worku, Eniyew Tegegne, Menichil Amsalu

Declaration of conflicting interests

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Funding

The author(s) received no financial support for the research, authorship, and/or publication of this article.

ORCID iD

Kalkidan Worku

Data availability statement

The given this article are all data are available from the corresponding author on reasonable request.

Appendix

References

Adewuya

A. O.

Hanlon

Medhin

Dewey

Alem

Worku

Prince

(2014). Perinatal common mental disorders and child survival in Ethiopia. Journal of Paediatrics and Child Health, 50(1), 57–63. https://doi.org/10.1111/jpc.12411

Alenko

Girma

Abera

Workicho

(2020). Children emotional and behavioural problems and its association with maternal depression in Jimma town, southwest Ethiopia. General psychiatry, 33(4), e100211. https://doi.org/10.1136/gpsych-2020-100211

Aliye

Tesfaye

Soboka

(2023). High rate of attention deficit hyperactivity disorder among children 6 to 17 years old in Southwest Ethiopia findings from a community-based study. BMC Psychiatry, 23(1), 144. https://doi.org/10.1186/s12888-023-04636-9

Anonymous . https://www.who.int/news-room/fact-sheets/detail/mental-health-strengthening-our-response).

Ashenafi

Kebede

Desta

Alem

(2000). Socio-demographic correlates of mental and behavioural disorders of children in southern Ethiopia. East African Medical Journal, 77(10), 565–569. https://doi.org/10.4314/eamj.v77i10.46715

Ashenafi

Kebede

Desta

Alem

(2001). Prevalence of mental and behavioural disorders in Ethiopian children. East African Medical Journal, 78(6), 308–311.

Ayano

Betts

Tait

Dachew

B. A.

Alati

(2021). Maternal depressive and anxiety symptoms and the risk of attention deficit hyperactivity disorder symptoms in offspring aged 17: findings from the Raine Study. Journal of Affective Disorders, 284, 149–156. https://doi.org/10.1016/j.jad.2021.02.024

Barican

J. L.

Yung

Schwartz

Zheng

Georgiades

Waddell

(2022). Prevalence of childhood mental disorders in high-income countries: A systematic review and meta-analysis to inform policymaking. Evidence-Based Mental Health, 25(1), 36–44. https://doi.org/10.1136/ebmental-2021-300277

Barsisa

Derajew

Haile

Mesafint

Shumet

(2021). Prevalence of common mental disorder and associated factors among mothers of under five year children at Arbaminch Town, South Ethiopia, 2019. PLoS One, 16(9), Article e0257973. https://doi.org/10.1371/journal.pone.0257973

10.

Beirão

Monte

Amaral

Longras

Matos

Villas-Boas

(2020). Depression in adolescence: A review. Middle East Current Psychiatry, 27(1), 50. https://doi.org/10.1186/s43045-020-00050-z

11.

Bitsko

R. H.

Claussen

A. H.

Lichstein

Black

L. I.

Jones

S. E.

Danielson

M. L.

Hoenig

J. M.

Davis Jack

S. P.

Brody

D. J.

Gyawali

Maenner

M. J.

Warner

Holland

K. M.

Perou

Crosby

A. E.

Blumberg

S. J.

Avenevoli

Kaminski

J. W.

Ghandour

R. M.

. Mental health surveillance among children – United States, 2013-2019. MMWR supplements. 2022;71(2);1–42. https://doi.org/10.15585/mmwr.su7102a1, https://www.cdc.gov/mmwr/volumes/71/su/su7102a1.htm. Accessed October 4, 2022.

12.

Bronsard

Alessandrini

Fond

Loundou

Auquier

Tordjman

Boyer

(2016). The prevalence of mental disorders among children and adolescents in the child welfare system: a systematic review and meta-analysis. Medicine (Baltimore), 95(7), Article e2622. https://doi.org/10.1097/MD.0000000000002622

13.

Cree

R. A.

Bitsko

R. H.

Robinson

L. R.

Holbrook

J. R.

Danielson

M. L.

Smith

Kaminski

J. W.

Kenney

M. K.

Peacock

(2018). Health care, family, and community factors associated with mental, behavioral, and developmental disorders and poverty among children aged 2-8 Years - United States, 2016. MMWR. Morbidity and mortality weekly report, 67(50), 1377–1383. https://doi.org/10.15585/mmwr.mm6750a1

14.

Dimitry

(2012). A systematic review on the mental health of children and adolescents in areas of armed conflict in the Middle East. Child: Care, Health and Development, 38(2), 153–161. https://doi.org/10.1111/j.1365-2214.2011.01246.x

15.

Engemann

Pedersen

C. B.

Arge

Tsirogiannis

Mortensen

P. B.

Svenning

J. C.

(2019). Residential green space in childhood is associated with lower risk of psychiatric disorders from adolescence into adulthood. Proceedings of the National Academy of Sciences of the United States of America, 116(11), 5188–5193. https://doi.org/10.1073/pnas.1807504116

16.

Fekadu

Alem

Hägglöf

(2006). The prevalence of mental health problems in Ethiopian child laborers. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 47(9), 954–959. https://doi.org/10.1111/j.1469-7610.2006.01617.x

17.

Gebeyehu

Kefale

Boka

Mengstu

Belayneh

Zeleke

(2019). Emotional and behavioral problems and associated factors among children and adolescents on highly active anti-retroviral therapy in public hospitals of west Gojjam zone, Amhara regional state of Ethiopia, 2018: a cross-sectional study. BMC Pediatrics, 19(1), 141. https://doi.org/10.1186/s12887-019-1453-3

18.

Ghandour

R. M.

Sherman

L. J.

Vladutiu

C. J.

Ali

M. M.

Lynch

S. E.

Bitsko

R. H.

Blumberg

S. J.

(2019). Prevalence and treatment of depression, anxiety, and conduct problems in US children. The Journal of Pediatrics, 206, 256–267. e3. https://doi.org/10.1016/j.jpeds.2018.09.021

19.

Girma

Tsehay

Mamaru

Abera

(2021). Depression and its determinants among adolescents in Jimma town, Southwest Ethiopia. PLoS One, 16(5), Article e0250927. https://doi.org/10.1371/journal.pone.0250927

20.

Greene

M. C.

Kane

J. C.

Bolton

Murray

L. K.

Wainberg

M. L.

Sim

Puffer

Ismael

Hall

B. J.

(2021). Assessing trauma and related distress in refugee youth and their caregivers: Should we be concerned about iatrogenic effects? Eur Child Adolesc Psychiatry, 30(9), 1437–1447. https://doi.org/10.1007/s00787-020-01635-z

21.

Gruebner

Rapp

M. A.

Adli

Kluge

Galea

Heinz

(2017). Cities and mental health. Deutsches Arzteblatt international, 114(8), 121–127. https://doi.org/10.3238/arztebl.2017.0121

22.

Kim

(2023). Surviving child abuse in people with mental illness: a Grounded theory approach. Journal of Interpersonal Violence, 38(3-4), 2828–2849. https://doi.org/10.1177/08862605221102486

23.

Isaksson

Deyessa

Berhane

Högberg

(2017). Early adversity and psychiatric symptoms - a prospective study on Ethiopian mothers and their children. BMC Psychiatry, 17(1), 344. https://doi.org/10.1186/s12888-017-1500-2

24.

Jebena

M. G.

Lindstrom

Belachew

Hadley

Lachat

Verstraeten

De Cock

Kolsteren

(2016). Food insecurity and common mental disorders among Ethiopian youth: Structural Equation modeling. PLoS One, 11(11), Article e0165931. https://doi.org/10.1371/journal.pone.0165931

25.

Jörns-Presentati

Napp

A. K.

Dessauvagie

A. S.

Stein

D. J.

Jonker

Breet

Charles

Swart

R. L.

Lahti

Suliman

Jansen

van den Heuvel

L. L.

Seedat

Groen

(2021). The prevalence of mental health problems in sub-Saharan adolescents: a systematic review. PLoS One, 16(5), Article e0251689. https://doi.org/10.1371/journal.pone.0251689

26.

Khoury

Tang

Y. L.

Bradley

Cubells

J. F.

Ressler

K. J.

(2010). Substance use, childhood traumatic experience, and posttraumatic stress disorder in an urban civilian population. Depression and Anxiety, 27(12), 1077–1086. https://doi.org/10.1002/da.20751

27.

Kinge

J. M.

Øverland

Flatø

Dieleman

Røgeberg

Magnus

M. C.

Evensen

Tesli

Skrondal

Stoltenberg

Vollset

S. E.

Håberg

Torvik

F. A.

(2021). Parental income and mental disorders in children and adolescents: Prospective register-based study. Int J Epidemiol, 50(5), 1615–1627. https://doi.org/10.1093/ije/dyab066

28.

Lebrun-Harris

L. A.

Ghandour

R. M.

Kogan

M. D.

Warren

M. D.

(2022). Five-year Trends in US children's health and well-being, 2016-2020. JAMA Pediatrics, 176(7), Article e220056. https://doi.org/10.1001/jamapediatrics.2022.0056

29.

Lian

Hui-Jing

Jia-Jie

(2013). Prevalence of ADHD in children of China: a systematic review and meta analysis, Chinese Journal of Public Health, 29(9), 1279.

30.

Lippard

E. T. C.

Nemeroff

C. B.

(2020). The Devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders. American Journal of Psychiatry, 177(1), 20–36. https://doi.org/10.1176/appi.ajp.2019.19010020

31.

Lippman

(1976). Psychiatry in Ethiopia. Canadian Psychiatric Association Journal, 21(6), 383–388. https://doi.org/10.1177/070674377602100604

32.

Lola

H. M.

Belete

(2019). Attention deficit hyperactivity disorder (ADHD) among children aged 6 to 17 years old living in Girja District, rural Ethiopia. Behav Neurol, 2019, 1753580.

33.

Lynch

McDonnell

Leahy

Gavin

McNicholas

(2022. Prevalence of mental health disorders in children and adolescents in the republic of Ireland: A systematic review. Irish Journal of Psychological Medicine, 40(1), 51–62. https://doi.org/10.1017/ipm.2022.46

34.

Mahat

Brøndbo

P. H.

Handegård

B. H.

Kvernmo

Javo

A. C.

(2021). Parent reports of children’s emotional and behavioral problems in a low- and middle- income country (LMIC): an epidemiological study of Nepali schoolchildren. PLoS One, 16(8), Article e0255596. https://doi.org/10.1371/journal.pone.0255596

35.

Martin

Hadwin

J. A.

(2022). The roles of sex and gender in child and adolescent mental health. JCPP Advances, 2(1), Article e12059. https://doi.org/10.1002/jcv2.12059

36.

Meshesha

H. S.

Johnson

(2020). A systematic review of culturally responsive approaches to child and adolescent mental health care in Ethiopia. Frontiers in Sociology, 5, 583864. https://doi.org/10.3389/fsoc.2020.583864.

37.

Mulatu

M S.

(1995). Prevalence and risk factors of psychopathology in Ethiopian children. Journal of the American Academy of Child & Adolescent Psychiatry, 34(1), 100–109. https://doi.org/10.1097/00004583-199501000-00020

38.

Mulu

G. B.

Mohammed

A. Y.

Kebede

W. M.

Atinafu

B. T.

Tarekegn

F. N.

Teshome

H. N.

Tadese

Wubetu

A. D.

(2022). Prevalence and associated factors of attention-deficit hyperactivity disorder among children aged 6-17 Years in North eastern Ethiopia. Ethiopian journal of health sciences, 32(2), 321–330. https://doi.org/10.4314/ejhs.v32i2.13

39.

Nyundo

Manu

Regan

Ismail

Chukwu

Dessie

Njau

Kaaya

S. F.

Smith Fawzi

M. C.

(2020). Factors associated with depressive symptoms and suicidal ideation and behaviours amongst sub-Saharan African adolescents aged 10-19 years: Cross-sectional study. Tropical Medicine and International Health: TM & IH, 25(1), 54–69. https://doi.org/10.1111/tmi.13336

40.

Office of the Surgeon, G . Publications and Reports of the Surgeon General, in Protecting youth mental health: The U.S. Surgeon General’s advisory. 2021. US Department of Health and Human Services.

41.

Organization (PAHO), P.A.H. accessed on 12/27/2022:https://www.paho.org/en/topics/mental-health

42.

Otten

Tibubos

A. N.

Schomerus

Brähler

Binder

Kruse

Ladwig

K. H.

Wild

P. S.

Grabe

H. J.

Beutel

M. E.

(2021). Similarities and differences of mental health in women and men: a systematic review of findings in three large German cohorts. Frontiers in Public Health, 9, 553071. https://doi.org/10.3389/fpubh.2021.553071.

43.

Pelgrims

Devleesschauwer

Guyot

Keune

Nawrot

T. S.

Remmen

Saenen

N. D.

Trabelsi

Thomas

Aerts

De Clercq

E. M.

(2021). Association between urban environment and mental health in Brussels, Belgium. BMC Public Health, 21(1), 635. https://doi.org/10.1186/s12889-021-10557-7

44.

Peterson

(2011). The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute.

45.

Ribeiro

W. S.

Grande

A. J.

Hoffmann

M. S.

Ziebold

McDaid

Fry

Peixoto

Miranda

King

Tomasi

C. D.

Faustino

Leone

Moraes

Schäfer

A. A.

Alves

Rosa

M. I.

Evans-Lacko

(2023). A systematic review of evidence-based interventions for child and adolescent mental health problems in low- and middle-income countries. Comprehensive Psychiatry, 121, 152358. https://doi.org/10.1016/j.comppsych.2022.152358.

46.

Ring-the-Alarm-TASKFORCE-REPORT.pdf . Ring the Alarm: The Crisis of black youth suicide in America. World Health Organiation. https://theactionalliance.org/sites/default/files/ring_the_alarm-_the_crisis_of_black_youth_suicide_in_america_copy.pdf (Accessed 4 October 2022).

47.

Sacco

(2022). A systematic review and meta-analysis on the prevalence of mental disorders among children and adolescents in Europe. European Child & Adolescent Psychiatry.

48.

Sathiyasusuman

(2011). Mental health services in Ethiopia: emerging public health issue. Public Health, 125(10), 714–716. https://doi.org/10.1016/j.puhe.2011.06.014

49.

Shiferaw

Bacha

Tsegaye

(2018). Prevalence of depression and its associated factors among orphan children in orphanages in Ilu Abba bor Zone, South west Ethiopia. Psychiatry Journal, 2018(164), 6865085.

50.

Stracke

Heinzl

Müller

A. D.

Gilbert

Thorup

A. A. E.

Paul

J. L.

Christiansen

(2023). Mental health is a family Affair—systematic review and meta-analysis on the associations between mental health problems in parents and children during the COVID-19 pandemic. International Journal of Environmental Research and Public Health, 20(5), 4485. https://doi.org/10.3390/ijerph20054485

51.

Meng

Yang

D'Arcy

(2022). The relationship between childhood maltreatment and mental health problems: coping strategies and social support act as mediators. BMC Psychiatry, 22(1), 359. https://doi.org/10.1186/s12888-022-04001-2

52.

Tadesse

(1999a). Childhood behavioural disorders in Ambo district, western Ethiopia. II. Validation of the RQC. Acta Psychiatrica Scandinavica - Supplement, 397, 98–101.

53.

Tadesse

A. W.

Berhane Tsehay

Girma Belaineh

Alemu

Y. B.

(2012). Behavioral and emotional problems among children aged 6-14 years on highly active antiretroviral therapy in Addis Ababa: a cross-sectional study. AIDS Care, 24(11), 1359-1367. https://doi.org/10.1080/09540121.2011.650677

54.

Tadesse

Kebede

Tegegne

Alem

(1999b). Childhood behavioural disorders in Ambo district, western Ethiopia. I. Prevalence estimates. Acta psychiatrica Scandinavica. Supplementum, 397, 92–97. https://doi.org/10.1111/j.1600-0447.1999.tb10700.x.

55.

Van Droogenbroeck

Spruyt

Keppens

(2018). Gender differences in mental health problems among adolescents and the role of social support: results from the Belgian health interview surveys 2008 and 2013. BMC Psychiatry, 18(1), 6. https://doi.org/10.1186/s12888-018-1591-4

56.

World Health Organiation . (1992). The ICD-10 classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines. World Health Organization.

57.

World Health Organiation . (2015). The European mental health action plan 2013–2020. World Health Organiation.

58.

World Health Organiation . (2022). World mental health report: Transforming mental health for all. World Health Organiation.

59.

World Health Organiation . accessed on 12/27/2022. https://www.who.int/news-room/fact-sheets/detail/mental-disorders

60.

World Health Organization (2020). Regional Office for the eastern, M., World Health Organization annual report 2019 WHO Country Office Lebanon: health for all. 2020. World Health Organization. Regional Office for the Eastern Mediterranean.

61.

World Health Organization (2021). Adolescent mental health. https://www.who.int/news-room/factsheets/detail/adolescent-mental-health (Accessed October 4, 2022).

62.

Yoon

(2022). Gender difference in the change of adolescents’ mental health and subjective wellbeing trajectories. European Child & Adolescent Psychiatry.

63.

Zeleke

W. A.

Hughes

T. L.

Kanyongo

(2021). Assessing the effectiveness of professional development training on autism and culturally responsive practice for educators and practitioners in Ethiopia. Frontiers in Psychiatry, 11, 11. https://doi.org/10.3389/fpsyt.2020.583674.

64.

Zhao

(2019a). Childhood maltreatment influences mental symptoms: The Mediating roles of emotional Intelligence and social support. Frontiers in Psychiatry, 10.

Mental illness in children and its determinants in Ethiopia: A systematic review and meta-analysis,2023

Abstract

Introduction

Methods

Result

Conclusion

Keywords

Introduction

Methods

Exploration approach for primary studies

Eligibility criteria

Inclusion criteria

Exclusion criteria

Outcome measurements

Data extraction

Operational definitions

Children

ADHD

Depression

Emotional Behavioral Problem (EBP)

Quality assessment

Statistical analysis

Ethics approval

Results

Exploration of original articles

Characteristics of original studies

Data management and analysis

Attention Deficit Hyperactivity (ADH) among children in Ethiopia

Emotional and behavioral problems (EBP) among children in Ethiopia

Depression among children in Ethiopia

Any mental illness among children in Ethiopia

Meta trim and fill analysis

Subgroup analysis

Sensitivity analysis

Associated factors of any mental illness among children in Ethiopia

Sexual abuse history

Parental socio-economic status

Resident and any mental illness among children

Gender and any mental illness among children

Discussion

Limitations of the study

Conclusion and recommendations

Footnotes

Acknowledgments

Author Contributions

Declaration of conflicting interests

Funding

ORCID iD

Data availability statement

Appendix

References