Aird WCEndothelial biomedicine. New York, NY: Cambridge University Press, 2007.
2.
Cooke JPFlow, NO, and atherogenesis. Proc Natl Acad Sci USA2003; 100: 768-770.
3.
Schachinger V., Britten MB, Zeiher AMPrognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation2000; 101: 1899-1906.
4.
Valkonen VP, Paiva H., Salonen JT, et al. Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine. Lancet2001; 358: 2127-2128.
5.
Böger RH , Sullivan LM, Schwedhelm E., et al. Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Circulation2009; 119: 1592-1600.
6.
Vallance P., Leone A., Calver A., et al. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet1992; 339: 572-575.
7.
Torondel B., Nandi M., Kelly P., Wojciak-Stothard B., Fleming I., Leiper J.Adenoviral mediated overexpression of DDAH improves vascular tone regulation. Vasc Med 2010. Online ahead of print publication: 10.1177/1358863X09360264.
8.
Cooke JPAsymmetrical dimethylarginine: The Uber marker?Circulation2004; 109: 1813-1818.
MacAllister RJ, Parry H., Kimoto M., et al. Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase. Br J Pharmacol1996; 119: 1533-1540.
11.
Leiper J., Nandi M., Torondel B., et al. Disruption of methyl-arginine metabolism impairs vascular homeostasis . Nat Med2007; 13: 198-203.
12.
Dayoub H., Achan V., Adimoolam S., et al. DDAH regulates NO synthesis: genetic and physiological evidence . Circulation2003; 108: 1043-1048.
13.
Jacobi J., Sydow K., von Degenfeld G., et al. Overexpression of dimethylarginine dimethylaminohydrolase (DDAH) reduces tissue ADMA levels and enhances angiogenesis. Circulation2005; 111: 1431-1438.
14.
Pope AJ, Karrupiah K., Kearns PN, Xia Y., Cardounel AJRole of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production. J Biol Chem2009; 284: 33,338-35,347.
15.
Boger RH, Bode-Boger SM, Szuba A., et al. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation1998; 98: 1842-1847.
16.
Abbasi F., Asagmi T., Cooke JP, et al. Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus. Am J Cardiol2001; 88: 1201-1203.
17.
Stuhlinger MC, Oka RK, Graf EE, et al Endothelial dysfunction induced by hyperhomocysteinemia: role of ADMA. Circulation2003; 108: 933-938.
18.
Kielstein JT , Zoccali C.Asymmetric dimethylarginine: a novel marker of risk and a potential target for therapy in chronic kidney disease. Curr Opin Nephrol Hypertens2008; 17: 609-615.
19.
Murray-Rust J., Leiper J., McAlister M., et al. Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase . Nat Struct Biol2001; 8: 679-683.
20.
Ito A., Tsao PS, Adimoolam S., Kimoto M., Ogawa T., Cooke JPNovel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation1999; 99: 3092-3095.
21.
Stuhlinger MC , Tsao PS, Her JH, Kimoto M., Balint RF, Cooke JPHomocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation2001; 104: 2569-2575.
22.
Lin KY, Ito A., Asagami T., et al. Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase . Circulation2002; 106: 987-992
Wilson A., Harada R., Nair N., Balasubramanian N., Cooke JPL-Arginine supplementation in peripheral arterial disease: no benefit and possible harm. Circulation2007; 116: 188-195.
25.
Von der Leyen HE, Gibbons GH, Morishita R., et al. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci U S A1995; 92: 1137-1141.
26.
Chen C-H., Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D.Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart . Science2008; 321: 1493-1495.
27.
Wang Y., Monzingo AF, Hu S., Schaller TH, Robertus JD, Fast W.Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry2009; 48: 8624-8635.