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Abstract

French

Background:

Epidermodysplasia verruciformis (EV) is a rare disorder characterized by widespread flat and common Verrucae. From 25% to 50% of EV cases are inherited, usually with an autosomal recessive pattern. An X-linked inheritance has also been reported. Many EV patients have a cellular immunity defect. HIV-associated lesions have been found to contain HPV-5, HPV-8, and HPV-20.

Objective:

We describe two HIV-positive Hispanic maternal half brothers who presented with asymptomatic polyangular papules and plaques on the face, trunk, and extremities and which first appeared 4–5 years prior. The histopathology is consistent with EV. HPV-8 was detected by in situ hybridization. The patients were treated with topical imiquimod for two months without improvement.

Conclusion:

To our knowledge, this is the first reported case of epidermodysplasia verruciformis in HIV-positive pediatric patients.

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Epidermodysplasia Verruciformis in Two Half Brothers with HIV Infection

Abstract

Background:

Objective:

Conclusion:

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References