To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin.
Methods
A 10-year-old girl with juxtapapillary CNV in the right eye and juxtapapillary and juxtafoveal CNV in the left eye associated with OND underwent PDT with verteporfin in both eyes.
Results
Visual acuity increased from 20/160 to 20/25 in the right eye and from 20/1000 to 20/25 in the left eye after two sessions of PDT and 2 years of follow-up. CNV showed no leakage after two PDT sessions in both eyes and no recurrence was observed.
Conclusions
Subfoveal CNV is an uncommon complication of OND and excellent anatomic and functional results can be obtained with PDT.
HarrisM.J., FineS.L., OwensS.L., GuzakS.V.Hemorrhagic complications of optic nerve drusen. Am J Ophtalmol1981; 92: 70–6.
2.
DiduzynJ.M., QuillenD.A., CantoreW.A., GardnerT.W.Optic disc drusen, peripapillary choroidal neovascularization, and POEMS syndrome. Am J Ophthalmol2002; 133: 275–6.
3.
SulluY., YildizL., ErkanD.Submacular surgery for choroidal neovascularization secondary to optic nerve drusen. Am J Ophthalmol2003; 136: 367–70.
4.
Verteporfin In Photodynamic Therapy Study Group. Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization - Verteporfin in photodynamic therapy report 2. Am J Ophthalmol2001; 131: 541–60.
5.
BresslerN.M., Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP) Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin. Two-year results of 2 randomized clinical trials. Arch Ophthalmol2001; 119: 198–207.
