Thoracic organ transplantation constitutes a significant proportion of all transplant procedures. Thoracic solid organ transplantation continues to be a burgeoning field of research. This article presents a review of remarkable literature published in 2017 regarding perioperative issues pertinent to the thoracic transplant anesthesiologists.
SheikhSIHayesDJrKirkbySETobiasJDTuminD.Age-dependent gender disparities in post lung transplant survival among patients with idiopathic pulmonary fibrosis. Ann Thorac Surg. 2017;103:441-446.
2.
YeungJCKruegerTYasufukuKet al. Outcomes after transplantation of lungs preserved for more than 12 h: a retrospective study. Lancet Respir Med. 2017;5:119-124.
3.
CrawfordTCGrimmJCMagruderJTet al. Lung transplant mortality is improving in recipients with a lung allocation score in the upper quartile. Ann Thorac Surg. 2017;103:1607-1613.
4.
MulvihillMSYerokunBADavisRPRanneyDNDaneshmandMAHartwigMG.Extracorporeal membrane oxygenation following lung transplantation: indications and survival [published online July 1, 2017]. J Heart Lung Transplant. doi:10.1016/j.healun.2017.06.014.
5.
HayesDJrTuminDBudevMMTobiasJDSt JohnRCKukrejaJ.Adverse outcomes associated with pulmonary hypertension in chronic obstructive pulmonary disease after bilateral lung transplantation. Respir Med. 2017;128:102-108.
6.
JeselLBarraudJLimHSet al. Early and late atrial arrhythmias after lung transplantation—incidence, predictive factors and impact on mortality. Circ J. 2017;81:660-667.
7.
KatsnelsonJWhitsonBATuminDet al. Lung transplantation with lungs from older donors: an analysis of survival in elderly recipients. J Surg Res. 2017;214:109-116.
8.
BaldwinMRSingerJPHuangDet al. Refining low physical activity measurement improves frailty assessment in advanced lung disease and survivors of critical illness. Ann Am Thorac Soc. 2017;14:1270-1279.
9.
AvrielAKlementAHJohnsonSRde PerrotMGrantonJ.Impact of left ventricular diastolic dysfunction on lung transplantation outcome in patients with pulmonary arterial hypertension. Am J Transplant. 2017;17:2705-2711. doi:10.1111/ajt.14352.
10.
SalmanJIusFSommerWet al. Mid-term results of bilateral lung transplant with postoperatively extended intraoperative extracorporeal membrane oxygenation for severe pulmonary hypertension. Eur J Cardiothorac Surg. 2017;52:163-170.
11.
GadreSKMinaiOAWangXFZhangQBudevMTonelliAR.Lung or heart-lung transplant in pulmonary arterial hypertension: what is the impact of systemic sclerosis?Exp Clin Transplant. 2017;15:676-684. doi:10.6002/ect.2016.0209.
12.
JompheVMailhotGDamphousseVet al. The impact of waiting list BMI changes on the short-term outcomes of lung transplantation [published online August 18, 2017]. Transplantation. doi:10.1097/TP.0000000000001919.
13.
ChambersDCYusenRDCherikhWSet al. The registry of the International Society for Heart and Lung Transplantation: thirty-fourth adult lung and heart-lung transplantation report-2017; focus theme: allograft ischemic time. J Heart Lung Transplant. 2017;36:1047-1059. doi:10.1016/j.healun.2017.07.016.
14.
HayesDJrSweetSCBendenCet al. Transplant center volume and outcomes in lung transplantation for cystic fibrosis. Transpl Int. 2017;30:371-377.
15.
HallDJBelliEVGreggJAet al. Two decades of lung retransplantation: a single-center experience. Ann Thorac Surg. 2017;103:1076-1083.
16.
SchumerEMRiceJDKistlerAMet al. Single versus double lung retransplantation does not affect survival based on previous transplant type. Ann Thorac Surg. 2017;103:236-240.
17.
AmburVTaghaviSJayarajanSet al. The impact of lungs from diabetic donors on lung transplant recipients. Eur J Cardiothorac Surg. 2017;51:285-290.
18.
Awori HayangaJW. Ex vivo lung perfusion: the makings of a game changer. J Heart Lung Transplant. 2017;36:720-721.
19.
HayesDJrHartwigMGTobiasJDTuminD.Lung transplant center volume ameliorates adverse influence of prolonged ischemic time on mortality. Am J Transplant. 2017;17:218-226.
20.
BangaAMohankaMMullinsJet al. Hospital length of stay after lung transplantation: independent predictors and association with early and late survival. J Heart Lung Transplant. 2017;36:289-296.
21.
van SuylenVLuijkBHoekRASet al. A multicenter study on long-term outcomes after lung transplantation comparing donation after circulatory death and donation after brain death. Am J Transplant. 2017;17:2679-2686. doi:10.1111/ajt.14339.
22.
PilarczykKHeckmannJCarstensHet al. Does traumatic donor cause of death influence outcome after lung transplantation? A single-centre analysis. Thorac Cardiovasc Surg. 2017;65:395-402.
23.
SlamaASchillabLBartaMet al. Standard donor lung procurement with normothermic ex vivo lung perfusion: a prospective randomized clinical trial. J Heart Lung Transplant. 2017;36:744-753.
24.
HijiyaKChen-YoshikawaTFKondoTet al. Bronchodilator inhalation during ex vivo lung perfusion improves posttransplant graft function after warm ischemia. Ann Thorac Surg. 2017;103:447-453.
25.
MehaffeyJHCharlesEJSharmaAKet al. Airway pressure release ventilation during ex vivo lung perfusion attenuates injury. J Thorac Cardiovasc Surg. 2017;153:197-204.
26.
HinskeLCHoechterDJSchroeerEet al. Predicting the necessity for extracorporeal circulation during lung transplantation: a feasibility study. J Cardiothorac Vasc Anesth. 2017;31:931-938.
27.
NazarniaSSubramaniamK.Pro: veno-arterial extracorporeal membrane oxygenation (ECMO) should be used routinely for bilateral lung transplantation. J Cardiothorac Vasc Anesth. 2017;31:1505-1508.
28.
SharmaNSHartwigMGHayesDJr.Extracorporeal membrane oxygenation in the pre and post lung transplant period. Ann Transl Med. 2017;5:74.
29.
HoechterDJShenYMKammererTet al. Extracorporeal circulation during lung transplantation procedures: a meta-analysis. ASAIO J. 2017;63:551-561.
30.
HayangaJWAShigemuraNAboagyeJKet al. ECMO support in lung transplantation: a contemporary analysis of hospital charges in the United States. Ann Thorac Surg. 2017;104:1033-1039.
31.
VerbeekGLMylesPSWestallGPet al. Intra-operative protective mechanical ventilation in lung transplantation: a randomised, controlled trial. Anaesthesia. 2017;72:993-1004.
32.
BhandarySStoiceaNJosephNWhitsonBEssandohM.Pro: inhaled pulmonary vasodilators should be used routinely in the management of patients undergoing lung transplantation. J Cardiothorac Vasc Anesth. 2017;31:1123-1126.
33.
RamadanMEShabsighMAwadH.Con: inhaled pulmonary vasodilators are not indicated in patients undergoing lung transplantation. J Cardiothorac Vasc Anesth. 2017;31:1127-1131.
BjörkbomEHämmainenPSchramkoA.Effects of perioperative fluid replacement therapy in lung transplant patients. Exp Clin Transplant. 2017;15:78-81.
36.
SmithIPearseBLFaulkeDJet al. Targeted bleeding management reduces the requirements for blood component therapy in lung transplant recipients. J Cardiothorac Vasc Anesth. 2017;31:426-433.
37.
BalciMKVayvadaMSalturkCKutluCAAriE.Incidence of early acute kidney injury in lung transplant patients: a single-center experience. Transplant Proc. 2017;49:593-598.
38.
VockDMDurheimMTTsuangWMet al. Survival benefit of lung transplantation in the modern era of lung allocation. Ann Am Thorac Soc. 2017;14:172-181.
39.
GottliebJSmitsJSchrammRet al. Lung transplantation in Germany since the introduction of the lung allocation score. Dtsch Arztebl Int. 2017;114:179-185.
40.
OshoAACastleberryAWYerokunBAet al. Clinical predictors and outcome implications of early readmission in lung transplant recipients. J Heart Lung Transplant. 2017;36:546-553.
41.
WrightMTakedaKMauroCet al. Dose-dependent association between amiodarone and severe primary graft dysfunction in orthotopic heart transplantation. J Heart Lung Transplant. 2017;36:1226-1233.
42.
LushajEBDhingraRChindhySet al. To use or not to use? Amiodarone before heart transplantation. Surgery. 2017;161:1273-1278.
43.
RiviniusRHelmschrottMRuhparwarAet al. Comparison of posttransplant outcomes in patients with no, acute, or chronic amiodarone use before heart transplantation. Drug Des Devel Ther. 2017;11:1827-1837.
44.
CooperLBMentzRJEdwardsLBet al. Amiodarone use in patients listed for heart transplant is associated with increased 1-year post-transplant mortality. J Heart Lung Transplant. 2017;36:202-210.
45.
JenningsDLBakerWL.Pre-cardiac transplant amiodarone use is not associated with postoperative mortality: an updated meta-analysis. Int J Cardiol. 2017;236:345-347.
46.
LundLHKhushKKCherikhWSet al. The registry of the International Society for Heart and Lung Transplantation: thirty-fourth adult heart transplantation report-2017; focus theme: allograft ischemic time. J Heart Lung Transplant. 2017;36:1037-1046.
47.
CastleberryAWDeVoreADSoutherlandKWet al. Assessing consequences of intraaortic balloon counterpulsation versus left ventricular assist devices at the time of heart transplantation. ASAIO J. 2016;62:232-239.
48.
GrimmJCMagruderJTCrawfordTCet al. Duration of left ventricular assist device support does not impact survival after US heart transplantation. Ann Thorac Surg. 2016;102:1206-1212.
49.
SecoMZhaoDFByromMJet al. Long-term prognosis and cost-effectiveness of left ventricular assist device as bridge to transplantation: a systematic review. Int J Cardiol. 2017;235:22-32.
50.
JhaSRHannuMKNewtonPJet al. Reversibility of frailty after bridge-to-transplant ventricular assist device implantation or heart transplantation. Transplant Direct. 2017;3:e167.
51.
GuhaANguyenDCruz-SolbesASet al. Risk stratification of patients with current generation continuous-flow left ventricular assist devices being bridged to heart transplantation [published online September 5, 2017]. ASAIO J. doi:10.1097/MAT.0000000000000635.
52.
SteffenRJBlackstoneEHSmediraNGet al. Optimal timing of heart transplant after HeartMate II left ventricular assist device implantation. Ann Thorac Surg. 2017;104:1569-1576.
53.
GulatiGOuyangDHaRBanerjeeD.Optimal timing of same-admission orthotopic heart transplantation after left ventricular assist device implantation. World J Cardiol. 2017;9:154-161.
54.
Barge-CaballeroEAlmenar-BonetLGonzalez-VilchezFet al. Clinical outcomes of temporary mechanical circulatory support as a direct bridge to heart transplantation: a nationwide Spanish registry [published online September 26, 2017]. Eur J Heart Fail. doi:10.1002/ejhf.956.
55.
BartfaySEDellgrenGLidénHet al. Are biventricular assist devices underused as a bridge to heart transplantation in patients with a high risk of postimplant right ventricular failure?J Thorac Cardiovasc Surg. 2017;153:360-367.e1.
56.
MagruderJTGrimmJCCrawfordTCet al. Survival after orthotopic heart transplantation in patients undergoing bridge to transplantation with the HeartWare HVAD versus the HeartMate II. Ann Thorac Surg. 2017;103:1505-1511.
57.
NestorovicEMGrupperAJoyceLDet al. Effect of pretransplant continuous-flow left ventricular assist devices on cellular and antibody-mediated rejection and subsequent allograft outcomes. Am J Cardiol. 2017;119:452-456.
58.
SeeSBClerkinKJKennelPJet al. Ventricular assist device elicits serum natural IgG that correlates with the development of primary graft dysfunction following heart transplantation. J Heart Lung Transplant. 2017;36:862-870.
59.
TchantchaleishviliVWoodKLCarlsonLAet al. Temporary mechanical circulatory support after orthotopic heart transplantation: a single-centre experience. Interact Cardiovasc Thorac Surg. 2017;25:41-46.
60.
TakedaKLiBGaranARet al. Improved outcomes from extracorporeal membrane oxygenation versus ventricular assist device temporary support of primary graft dysfunction in heart transplant. J Heart Lung Transplant. 2017;36:650-656.
61.
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62.
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63.
NguyenVPMahrCMokadamNAPalJSmithJWDardasTF.The benefit of donor-recipient matching for patients undergoing heart transplantation. J Am Coll Cardiol. 2017;69:1707-1714.
64.
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65.
PeledYLaveeJAradMet al. The impact of gender mismatching on early and late outcomes following heart transplantation. ESC Heart Fail. 2017;4:31-39.
66.
JalowiecAGradyKLWhite-WilliamsC.Mortality, rehospitalization, and post-transplant complications in gender-mismatched heart transplant recipients. Heart Lung. 2017;46:265-272.
67.
BergenfeldtHStehlikJHöglundPAnderssonBNilssonJ.Donor-recipient size matching and mortality in heart transplantation: influence of body mass index and gender. J Heart Lung Transplant. 2017;36:940-947.
68.
AwadMCzerLSMirochaJet al. Similar mortality and morbidity of orthotopic heart transplantation for patients 70 years of age and older compared with younger patients. Transplant Proc. 2016;48:2782-2791.
69.
BosseauCLelongBPattierSet al. Heart transplantation in selected patients aged 60 years and older: a two-decade retrospective and multicentre analysis. Eur J Cardiothorac Surg. 2017;51:893-901.
70.
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71.
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IyerAChewHCGaoLet al. Pathophysiological trends during withdrawal of life support: implications for organ donation after circulatory death. Transplantation. 2016;100:2621-2629.
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MesserSJAxellRGColahSet al. Functional assessment and transplantation of the donor heart after circulatory death. J Heart Lung Transplant. 2016;35:1443-1452.
74.
GaleoneAVarnousSLebretonGet al. Impact of cardiac arrest resuscitated donors on heart transplant recipients’ outcome. J Thorac Cardiovasc Surg. 2017;153:622-630.
75.
ChanJLKobashigawaJAReichHJet al. Intermediate outcomes with ex-vivo allograft perfusion for heart transplantation. J Heart Lung Transplant. 2017;36:258-263.
76.
ArdehaliAEsmailianFDengMet al. Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial. Lancet. 2015;385:2577-2584.
77.
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78.
LeongDAintablianTKittlesonMet al. Prolonged corrected QT interval in the donor heart: is there a risk? [published online June 11, 2017]. Clin Transplant. doi:10.1111/ctr.12996.
79.
JosephJTMulvihillMSYerokunBABellSMMilanoCAHartwigMG.Elevated donor hemoglobin A1c does not impair early survival in cardiac transplant recipients [published online June 10, 2017]. Clin Transplant. doi:10.1111/ctr.12995.
80.
FreundtMPhilippAKolatPet al. Impact of elevated donor troponin I as predictor of adverse outcome in adult heart transplantation: a single-center experience [published online September 18, 2017]. Thorac Cardiovasc Surg. doi:10.1055/s-0037-1606363.
81.
LazzeriCGuettiCMigliaccioMLCiapettiMPerisA.The utility of serial echocardiograms for organ procurement in brain death [published online October 15, 2017]. Clin Transplant. doi:10.1111/ctr.13094.
82.
ChenCWSprysMHGaffeyACet al. Low ejection fraction in donor hearts is not directly associated with increased recipient mortality. J Heart Lung Transplant. 2017;36:611-615.
83.
MadanSSaeedOVlismasPet al. Outcomes after transplantation of donor hearts with improving left ventricular systolic dysfunction. J Am Coll Cardiol. 2017;70:1248-1258.
84.
CrawfordTCMagruderJTGrimmJCet al. The paradoxical relationship between donor distance and survival after heart transplantation. Ann Thorac Surg. 2017;103:1384-1391.
85.
ChanJLKobashigawaJAAintablianTLet al. Vasoplegia after heart transplantation: outcomes at 1 year. Interact Cardiovasc Thorac Surg. 2017;25:212-217.
86.
TrubyLKTakedaKFarrMet al. Incidence and impact of on-cardiopulmonary bypass vasoplegia during heart transplantation. ASAIO J. 2018;64:43-51.
87.
VarelaNGolvanoMPérez-PevidaB.Safety of sugammadex for neuromuscular reversal in cardiac transplant patients. J Cardiothorac Vasc Anesth. 2016;30:e37.
88.
JahangirifardAAhmadiZHNaghashzadehFet al. Prophylactic fibrinogen decreases postoperative bleeding but not acute kidney injury in patients undergoing heart transplantation [published online January 1, 2017]. Clin Appl Thromb Hemost. doi:10.1177/1076029617731625.
89.
JahangirifardARazaviMRAhmadiZHForozeshfardM.Effect of desmopressin on the amount of bleeding and transfusion requirements in patients undergoing heart transplant surgery. Basic Clin Pharmacol Toxicol. 2017;121:175-180.
