The year 2020 was a monumental year in medicine, and this review focuses on selected articles for cardiothoracic anesthesiologists and perioperative physicians involved in the care of heart and lung transplant patients. In the field of lung transplantation, significant strides were made in our knowledge of risk stratification during the preoperative assessment of potential recipients, perioperative transfusion medicine, and the administration of coagulation factor concentrates. In addition, variations in perioperative management and outcomes between institutions were studied across an assortment of metrics regarding lung transplantation, including case volumes and anesthetic practices. Transitioning to topics in the field of heart transplantation, consideration was given to recipients with adult congenital heart disease, and separately, approaches to expanding the donor pool through donation after circulatory death. With regard to preoperative support, outcomes for the total artificial heart as well as the MitraClip as bridges to transplantation were published.
Hernandez-MorganMNeelankavilJGroganTHongBWingertTMethangkoolE.Preoperative anemia as a risk factor for postoperative outcomes in patients undergoing lung transplantation. J Cardiothorac Vasc Anesth. Published online October 28, 2020. doi:10.1053/j.jvca.2020.10.045
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KanaparthiJKashemMASuryapalamM, et al. Prior and perioperative revascularization does not affect survival in lung transplant patients. Ann Thorac Surg. 2020;109:1677-1683.
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WollFMohanMBollineniS, et al. Characteristics and outcomes of lung transplant candidates with preexisting renal dysfunction. Transplant Proc. 2020;52:302-308.
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VahidySLiDHirjiA, et al. Pretransplant opioid use and survival after lung transplantation. Transplantation. 2020;104:1720-1725.
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PenaJJBottigerBAMiltiadesAN.Perioperative management of bleeding and transfusion for lung transplantation. Semin Cardiothorac Vasc Anesth. 2020;24:74-83.
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SeayTGuinnNMaisonaveY, et al. The association of increased FFP:RBC transfusion ratio to primary graft dysfunction in bleeding lung transplantation patients. J Cardiothorac Vasc Anesth. 2020;34:3024-3032.
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HuddlestonSJJacksonSKaneK, et al. Separate effect of perioperative recombinant human factor VIIa administration and packed red blood cell transfusions on midterm survival in lung transplantation recipients. J Cardiothorac Vasc Anesth. 2020;34:3013-3020.
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JawitzOKRamanVBrynerBSKlapperJHartwigMG.Center volume and primary graft dysfunction in patients undergoing lung transplantation in the United States—a cohort study. Transpl Int. 2021;34:194-203.
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RanganathNKMalasJChenS, et al. High lung transplant center volume is associated with increased survival in hospitalized patients. Ann Thorac Surg. 2021;111:1652-1658. doi:10.1016/j.athoracsur.2020.06.124
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OshoAABishwaiMMHengEE, et al., Failure to rescue in the era of the lung allocation score: the impact of center volume. Am J Surg. 2020;220:793-799.
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SubramaniamKDel RioMJWilkeyBJ, et al. Anesthetic management of lung transplantation: results from a multicenter, cross-sectional survey by the society for advancement of transplant anesthesia. Clin Transplant. 2020;34:e13996.
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MartinAKYalamuriSMWilkeyBJ, et al. The impact of anesthetic management on perioperative outcomes in lung transplantation. J Cardiothorac Vasc Anesth. 2020;34:1669-1680.
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CholankerilGPodboyAAlshuwaykhOA, et al. Early impact of COVID-19 on solid organ transplantation in the United States. Transplantation. 2020;104:2221-2224.
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LoupyAAubertOReesePPBasteinOBayerFJacquelineC.Organ procurement and transplantation during the COVID-19 pandemic. Lancet. 2020;395:e95-e96.
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HalpernSEOlasoDGKrischakMK, et al. Lung transplantation during the COVID-19 pandemic: safely navigating the new “normal.” Am J Transplant. 2020;20:3094-3105.
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CypelMKeshavjeeS.When to consider lung transplantation for COVID-19. Lancet Respir Med. 2020;8:944-946.
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BharatAQuerreyMMarkovNS, et al. Lung transplantation for patients with severe COVID-19. Sci Transl Med. 2020;12:eabe4282.
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LangCJakschPHodaMA, et al. Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient. Lancet Respir Med. 2020;8:1057-1060.
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HanWZhuMChenJ, et al. Lung transplantation for elderly patients with end-stage COVID-19 pneumonia. Ann Surg. 2020;272:e33-e34.
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CeulemansLJvan SlambrouckJDe LaynP, et al. Successful double-lung transplantation from a donor previously infected with SARS-CoV-2. Lancet Respir Med. 2021; 9:315-318.
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YukiK.Anesthetic management for heart transplantation in adults with congenital heart disease. Transl Perioper Pain Med. 2020;7:248-252.
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BecherPMSchrageBWeimannJ, et al. Clinical characteristics and outcomes of patients with adult congenital heart disease listed for heart and heart-lung transplantation in the Eurotransplant region. J Heart Lung Transplant. Published online July 25, 2020. doi:10.1016/j.healun.2020.07.012
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KinsellaAAlbaACAlvarezJS, et al. Comparison of heart transplantation outcomes: adult congenital heart disease vs matched cardiac patients in a quaternary reference centre. Can J Cardiol. 2020;36:1208-1216.
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RiggsKWZafarFRadziYYuPJBryantR3rdMoralesDLS. Adult congenital heart disease: current early expectations after cardiac transplantation. Ann Thorac Surg. 2020;109:480-486.
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GuarientoADoulamisIPDuiganT, et al. Mitochondrial transplantation for myocardial protection in ex-situ perfused hearts donated after circulatory death. J Heart Lung Transplant. Published online June 29, 2020. doi:10.1016/j.healun.2020.06.
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NgaiJMasunoKMoazamiN.Anesthetic considerations during heart transplantation using donation after circulatory death. J Cardiothorac Vasc Anesth. 2020;34:3073-3077.
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MesserSCernicSPageA, et al. A 5-year single-center early experience of heart transplantation from donation after circulatory-determined death donors. J Heart Lung Transplant. 2020;39:1463-1475.
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DavidCHLacostePNanjaiahP, et al. A heart transplant after total artificial heart support: initial and long-term results. Eur J Cardiothorac Surg. 2020;58:1175-1181.
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CarrierMMoriguchiJShahKB, et al. Outcomes after heart transplantation and total artificial heart implantation: a multicenter study. J Heart Lung Transplant. 2021;40:220-228.
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GodinoCMunafoAScottiA, et al. MitraClip in secondary mitral regurgitation as a bridge to heart transplantation: 1-year outcomes from the International MitraBridge Registry. J Heart Lung Transplant. 2020;39:1353-1362.
