ADHD and Chinese developmental dyslexia (DD) have a very high comorbidity rate; however, which cognitive deficits characterize the comorbidity and when they occur during cognitive processing are still under debate.
Methods:
Rapid automatic naming (RAN) tasks with eye-movement tracking were conducted with 75 children who were typically developing, had comorbid ADHD and DD, had only ADHD, and had only DD.
Results:
The clinical groups had longer first fixation durations than the control for RAN digits. Temporal eye-movement measures, such as gaze duration and total reading time, were found to vary between the comorbidity and ADHD groups. Spatial eye-movement measures, such as regression probability and incoming saccade amplitude, differed between the comorbidity and DD groups.
Conclusions:
These results indicate that investigation with eye-movement measures combined with RAN tasks can strengthen the understanding of the pathogenesis of comorbid ADHD and DD.
AdlerL. A.FaraoneS. V.SpencerT. J.BerglundP.AlperinS.KesslerR. C. (2017). The structure of adult ADHD. International Journal of Methods in Psychiatric Research, 26(1), e1555. https://doi.org/10.1002/mpr.1555
2.
Al DahhanN. Z.HalversonK.PeekC. P.WilmotD.D’MelloA.RomeoR. R.MeegodaO.ImhofA.WadeK.SridharA.FalkeE.CentanniT. M.GabrieliJ. D. E.ChristodoulouJ. A. (2022). Dissociating executive function and ADHD influences on reading ability in children with dyslexia. Cortex, 153, 126–142. https://doi.org/10.1016/j.cortex.2022.03.025
3.
Al DahhanN. Z.KirbyJ. R.BrienD. C.GuptaR.HarrisonA.MunozD. P. (2020). Understanding the biological basis of dyslexia at a neural systems level. Brain communications, 2(2), fcaa173. https://doi.org/10.1093/braincomms/fcaa173
4.
Al DahhanN. Z.KirbyJ. R.BrienD. C.MunozD. P. (2017). Eye movements and articulations during a letter naming speed task: children with and without dyslexia. Journal of Learning Disabilities, 50(3), 275–285. https://doi.org/10.1177/0022219415618502
5.
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). American Psychiatric Publishing.
6.
BarkleyR. A. (2003). Issues in the diagnosis of attention-deficit/hyperactivity disorder in children. Brain & Development, 25(2), 77–83. https://doi.org/10.1016/s0387-7604(02)00152-3
7.
BoadaR.WillcuttE. G.PenningtonB. F. (2012). Understanding the comorbidity between dyslexia and attention-deficit/hyperactivity disorder. Topics in Language Disorders, 32(3), 264–284. https://doi.org/10.1097/TLD.0b013e31826203ac
8.
CaldaniS.AcquavivaE.MoscosoA.PeyreH.DelormeR.BucciM. P. (2022). Reading performance in children with ADHD: An eye-tracking study. Annals of Dyslexia, 72(3), 552–565. https://doi.org/10.1007/s11881-022-00269-x
9.
CaldaniS.GerardC. L.PeyreH.BucciM. P. (2020). Visual attentional training improves reading capabilities in children with dyslexia: An eye tracker study during a reading task. Brain Sciences, 10(8), E558. https://doi.org/10.3390/brainsci10080558
10.
CaoF.YanX.WangZ.LiuY.WangJ.SprayG. J.DengY. (2017). Neural signatures of phonological deficits in Chinese developmental dyslexia. NeuroImage, 146, 301–311. https://doi.org/10.1016/j.neuroimage.2016.11.051
11.
CapriT.SantoddiE.FabioR. A. (2020). Multisource interference task paradigm to enhance automatic and controlled processes in ADHD. Research in Developmental Disabilities, 97, 103542. https://doi.org/10.1016/j.ridd.2019.103542
12.
CuiX.WangJ.ChangY.SuM.ShermanH. T.WuZ.WangY.ZhouW. (2020). Visual search in Chinese children with Attention Deficit/hyperactivity disorder and comorbid developmental dyslexia: Evidence for pathogenesis from eye movements. Frontiers in Psychology, 11, 880. https://doi.org/10.3389/fpsyg.2020.00880
13.
DeansP.O’LaughlinL.BrubakerB.GayN.KrugD. (2010). Use of eye movement tracking in the differential diagnosis of attention deficit hyperactivity disorder (ADHD) and reading disability. Psychology, 1(4), 238–246. https://doi.org/10.4236/psych.2010.14032
DencklaM. B.RudelR. (1974). Rapid “automatized” naming of pictured objects, colors, letters and numbers by normal children. Cortex, 10, 186–202. https://doi.org/10.1016/S0010-9452(74)80009-2
16.
DharM.BeenP. H.MinderaaR. B.AlthausM. (2008). Distinct information processing characteristics in dyslexia and ADHD during a covert orienting task: An event-related potential study. Clinical Neurophysiology, 119(9), 2011–2025. https://doi.org/10.1016/j.clinph.2008.05.027
17.
FabioR. A. (2017). The study of automatic and controlled processes in ADHD: A reread and a new proposal. Mediterranean Journal of Clinical Psychology, 5(1), 1–33. https://doi.org/10.6092/2282-1619/2017.5.1507
18.
FaccioliC.PeruA.RubiniE.TassinariG. (2008). Poor readers but compelled to read: Stroop effects in developmental dyslexia. Child Neuropsychology, 14(3), 277–283. https://doi.org/10.1080/09297040701290040
19.
FisherS. E.DeFriesJ. C. (2002). Developmental dyslexia: Genetic dissection of a complex cognitive trait. Nature Reviews Neuroscience, 3(10), 767–780. https://doi.org/10.1038/nrn936
20.
GeorgiouG. K.PapadopoulosT. C.KaizerE. L. (2014). Different RAN components relate to reading at different points in time. Reading and Writing, 27(8), 1379–1394. https://doi.org/10.1007/s11145-014-9496-1
21.
GeorgiouG. K.PapadopoulosT. C.ZarounaE.ParrilaR. (2012). Are auditory and visual processing deficits related to developmental dyslexia?Dyslexia, 18(2), 110–129. https://doi.org/10.1002/dys.1439
22.
Gonçalves-GuedimT. F.CrenitteP. A. P. (2015). Performance of phonological processing in children with attention deficit hyperactivity disorder. Psychology, 6(10), 1331–1339. https://doi.org/10.4236/psych.2015.610130
23.
GouldT. D.BastainT. M.IsraelM. E.HommerD. W.CastellanosF. X. (2001). Altered performance on an ocular fixation task in attention-deficit/hyperactivity disorder. Biological Psychiatry, 50(8), 633–635. https://doi.org/10.1016/s0006-3223(01)01095-2
24.
InhoffA. W. (1984). Two stages of word processing during eye fixations in the reading of prose. Journal of Verbal Learning and Verbal Behavior, 23(5), 612–624. https://doi.org/10.1016/s0022-5371(84)90382-7
KariukiS. M.NewtonC. R. J. C.AbubakarA.BittaM. A.OdhiamboR.Phillips OwenJ. (2020). Evaluation of psychometric properties and factorial structure of ADHD module of K-SADS-PL in children from rural Kenya. Journal of Attention Disorders, 24(14), 2064–2071. https://doi.org/10.1177/1087054717753064
27.
KaufmanJ.BirmaherB.BrentD.RaoU.FlynnC.MoreciP.WilliamsonD.RyanN. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 980–988. https://doi.org/10.1097/00004583-199707000-00021
28.
KlieglR.MassonM. E. J.RichterE. M. (2010). A linear mixed model analysis of masked repetition priming. Visual Cognition, 18(5), 655–681. https://doi.org/10.1080/13506280902986058
29.
LangerN.BenjaminC.BeckerB. L.GaabN. (2019). Comorbidity of reading disabilities and ADHD: Structural and functional brain characteristics. Human Brain Mapping, 40(9), 2677–2698. https://doi.org/10.1002/hbm.24552
30.
LevinsonO.HersheyA.FarahR.Horowitz-KrausT. (2018). Altered functional connectivity of the executive functions network during a Stroop task in children with reading difficulties. Brain Connectivity, 8(8), 516–525. https://doi.org/10.1089/brain.2018.0595
31.
LiuY.GeorgiouG. K.ZhangY.LiH.LiuH.SongS.KangC.ShiB.LiangW.PanJ.ShuH. (2017). Contribution of cognitive and linguistic skills to word-reading accuracy and fluency in Chinese. International Journal of Educational Research, 82, 75–90. https://doi.org/10.1016/j.ijer.2016.12.005
32.
LúcioP. S.SalumG. A.RohdeL. A.SwardfagerW.GadelhaA.VandekerckhoveJ.PanP. M.PolanczykG. V.do RosárioM. C.JackowskiA. P.MariJ. J.Cogo-MoreiraH. (2017). Poor stimulus discriminability as a common neuropsychological deficit between ADHD and reading ability in young children: A moderated mediation model. Psychological Medicine, 47(2), 255–266. https://doi.org/10.1017/S0033291716002531
33.
MacLeodC. M. (1991). Half a century of research on the stroop effect: An integrative review. Psychological Bulletin, 109, 163–203. https://doi.org/10.1037/0033-2909.109.2.163
34.
MartinN. C.LevyF.PiekaJ.HayD. A. (2006). A genetic study of Attention Deficit Hyperactivity Disorder, Conduct Disorder, Oppositional Defiant Disorder and Reading Disability: Aetiological overlaps and implications. International Journal of Disability, Development and Education, 53(1), 21–34. https://doi.org/10.1080/10349120500509992
35.
MohammadhasaniN.CaprìT.NucitaA.IannizzottoG.FabioR. A. (2020). Atypical visual scan path affects remembering in ADHD. Journal of the International Neuropsychological Society, 26(6), 557–566. https://doi.org/10.1017/S135561771900136X
36.
MourikR. V.OosterlaanJ.SergeantJ. A. (2005). The stroop revisited: A meta-analysis of interference control in AD/HD. Journal of Child Psychology and Psychiatry, 46(2), 150–165. https://doi.org/10.1111/j.1469-7610.2004.00345.x
37.
NiggJ. T.HinshawS. P.CarteE. T.TreutingJ. J. (1998). Neuropsychological correlates of childhood attention-deficit/hyperactivity disorder: Explainable by comorbid disruptive behavior or reading problems?Journal of Abnormal Psychology, 107(3), 468–480. https://doi.org/10.1037/0021-843X.107.3.468
38.
Nilsson BenfattoM.Öqvist SeimyrG.YggeJ.PansellT.RydbergA.JacobsonC. (2016). Screening for dyslexia using eye tracking during reading. PLoS One, 11(12), e0165508. https://doi.org/10.1371/journal.pone.0165508
39.
NortonE. S.WolfM. (2012). Rapid automatized naming (RAN) and reading fluency: Implications for understanding and treatment of reading disabilities. Annual Review of Psychology, 63(1), 427–452. https://doi.org/10.1146/annurev-psych-120710-100431
40.
PangX.WangH.DillS. E.BoswellM.PangX.SinghM.RozelleS. (2021). Attention Deficit Hyperactivity Disorder (ADHD) among elementary students in rural China: Prevalence, correlates, and consequences. Journal of Affective Disorders, 293, 484–491. https://doi.org/10.1016/j.jad.2021.06.014
41.
PanJ.YanM.LaubrockJ.ShuH.KlieglR. (2013). Eye-voice span during rapid automatized naming of digits and dice in Chinese normal and dyslexic children. Developmental Science, 16(6), 967–979. https://doi.org/10.1111/desc.12075
42.
PenningtonB. F.GroisserD.WelshM. C. (1993). Contrasting cognitive deficits in attention deficit hyperactivity disorder versus reading disability. Developmental Psychology, 29(3), 511–523. https://doi.org/10.1037/0012-1649.29.3.511
43.
PetersonB. S.PotenzaM. N.WangZ.ZhuH.MartinA.MarshR.PlessenK. J.YuS. (2009). An FMRI study of the effects of psychostimulants on default-mode processing during Stroop task performance in youths with ADHD. American Journal of Psychiatry, 166(11), 1286–1294. https://doi.org/10.1176/appi.ajp.2009.08050724
44.
ProtopapasA.ArchontiA.SkaloumbakasC. (2007). Reading ability is negatively related to Stroop interference. Cognitive Psychology, 54(3), 251–282. https://doi.org/10.1016/j.cogpsych.2006.07.003
45.
PurvisK. L.TannockR. (2000). Phonological processing, not inhibitory control, differentiates ADHD and reading disability. Journal of the American Academy of Child and Adolescent Psychiatry, 39(4), 485–494. https://doi.org/10.1097/00004583-200004000-00018
46.
RamusF. (2003). Developmental dyslexia: Specific phonological deficit or general sensorimotor dysfunction?Current Opinion in Neurobiology, 13(2), 212–218. https://doi.org/10.1016/S0959-4388(03)00035-7
47.
RapportM. D.ChungK. M.ShoreG.IsaacsP. (2001). A conceptual model of child psychopathology: Implications for understanding attention deficit hyperactivity disorder and treatment efficacy. Journal of Clinical Child & Adolescent Psychology, 30(1), 48–58. https://doi.org/10.1207/s15374424jccp3001_6
48.
RaynerK. (1998). Eye movements in reading and information processing: 20 years of research. Psychological Bulletin, 124, 372–422. https://doi.org/10.1037/0033-2909.124.3.372
49.
RucklidgeJ. J.TannockR. (2002). Neuropsychological profiles of adolescents with ADHD: Effects of reading difficulties and gender. Journal of Child Psychology and Psychiatry, 43(8), 988–1003. https://doi.org/10.1111/1469-7610.00227
50.
SamuelsS. J. (1999). Developing reading fluency in learning-disabled students. In SternbergR. J.Spear-SwerlingL. (Eds.), Perspectives on learning disabilities (pp. 176–189). Routledge.
ShenC.JiangQ.LuoY.LongJ.TaiX.LiuS. (2021). Stroop interference in children with developmental dyslexia: An event-related potentials study. Medicine, 100(25), e26464. https://doi.org/10.1097/MD.0000000000026464
54.
ShuH.McBride-ChangC.WuS.LiuH. (2006). Understanding Chinese developmental dyslexia: Morphological awareness as a core cognitive construct. Journal of Education & Psychology, 98(1), 122–133. https://doi.org/10.1037/0022-0663.98.1.122
55.
SilversteinM. J.FaraoneS. V.LeonT. L.BiedermanJ.SpencerT. J.AdlerL. A. (2020). The relationship between executive function deficits and DSM-5-Defined ADHD symptoms. Journal of Attention Disorders, 24(1), 41–51. https://doi.org/10.1177/1087054718804347
56.
StroopJ. R. (1935). Studies of interference in serial verbal reactions. Journal of Experimental Psychology, 18, 643–662. https://doi.org/10.1037/h0054651
57.
SørensenL.PlessenK. J.AdolfsdottirS.LundervoldA. J. (2014). The specificity of the Stroop interference score of errors to ADHD in boys. Journal of Child Neuropsychology, 20(6), 677–691. https://doi.org/10.1080/09297049.2013.855716
58.
TannockR.MartinussenR.FrijtersJ. (2000). Naming speed performance and stimulant effects indicate effortful, semantic processing deficits in attention-deficit/hyperactivity disorder. Journal of Abnormal Child Psychology, 28(3), 237–252. https://doi.org/10.1023/a:1005192220001
59.
TürkanB. N.AmadoS.ErcanE. S.PerçinelI. (2016). Comparison of change detection performance and visual search patterns among children with/without ADHD: Evidence from eye movements. Research in Developmental Disabilities, 49-50, 205–215. https://doi.org/10.1016/j.ridd.2015.12.002
60.
VellutinoF. R.FletcherJ. M.SnowlingM. J.ScanlonD. M. (2004). Specific reading disability (dyslexia): What have we learned in the past four decades?Journal of Child Psychology and Psychiatry, 45(1), 2–40. https://doi.org/10.1046/j.0021-9630.2003.00305.x
61.
VidyasagarT. R.PammerK. (2010). Dyslexia: A deficit in visuo-spatial attention, not in phonological processing. Trends in Cognitive Sciences, 14(2), 57–63. https://doi.org/10.1016/j.tics.2009.12.003
62.
WangE.SunM.TaoY.GaoX.GuoJ.ZhaoC.LiH.QianQ.WuZ.WangY.SunL.SongY. (2017). Attentional selection predicts rapid automatized naming ability in Chinese-speaking children with ADHD. Scientific Reports, 7(1), 939. https://doi.org/10.1038/s41598-017-01075-x
63.
WangJ. J.BiH. Y.GaoL. Q.WydellT. N. (2010). The visual magnocellular pathway in Chinese-speaking children with developmental dyslexia. Neuropsychologia, 48(12), 3627–3633. https://doi.org/10.1016/j.neuropsychologia.2010.08.015
64.
WeiX.YuJ. W.ShaverD. (2014). Longitudinal effects of ADHD in children with learning disabilities or emotional disturbances. Exceptional Children, 80(2), 205–219. https://doi.org/10.1177/001440291408000205
65.
WhippleB. D.NelsonJ. M. (2016). Naming speed of adolescents and young adults with attention deficit hyperactivity disorder: Differences in alphanumeric versus color/object naming. Archives of Clinical Neuropsychology, 31(1), 66–78. https://doi.org/10.1093/arclin/acv061
66.
WillcuttE. G.BetjemannR. S.McGrathL. M.ChhabildasN. A.OlsonR. K.DeFriesJ. C.PenningtonB. F. (2010). Etiology and neuropsychology of comorbidity between RD and ADHD: The case for multiple-deficit models. Cortex, 46(10), 1345–1361. https://doi.org/10.1016/j.cortex.2010.06.009
67.
WillcuttE. G.PenningtonB. F.BoadaR.OglineJ. S.TunickR. A.ChhabildasN. A.OlsonR. K. (2001). A comparison of the cognitive deficits in reading disability and attention-Deficit/hyperactivity disorder. Journal of Abnormal Psychology, 110(1), 157–172. https://doi.org/10.1037//0021-843x.110.1.157
WillcuttE. G.PenningtonB. F.OlsonR. K.ChhabildasN.HulslanderJ. (2005). Neuropsychological analyses of comorbidity between reading disability and Attention Deficit Hyperactivity Disorder: In search of the common deficit. Developmental Neuropsychology, 27(1), 35–78. https://doi.org/10.1207/s15326942dn2701_3
70.
WuY. J.YangW. H.WangQ. X.YangS.HuX. Y.JingJ.LiX. H. (2018). Eye-movement patterns of Chinese children with developmental dyslexia during the Stroop test. Biomedical and Environmental Sciences, 31(9), 677–685. https://doi.org/10.3967/bes2018.092
71.
WuZ. M.WangP.LiuL.LiuJ.CaoX. L.SunL.CaoQ. J.YangL.WangY. F.YangB. R. (2022). ADHD-inattentive versus ADHD-Combined subtypes: A severity continuum or two distinct entities? A comprehensive analysis of clinical, cognitive and neuroimaging data. Journal of Psychiatric Research, 149, 28–36. https://doi.org/10.1016/j.jpsychires.2022.02.012
72.
YangL.LiC.LiX.ZhaiM.AnQ.ZhangY.ZhaoJ.WengX. (2022). Prevalence of developmental dyslexia in primary school children: A systematic review and meta-analysis. Brain Sciences, 12(2), 240. https://doi.org/10.3390/brainsci12020240
73.
YanM.PanJ.LaubrockJ.KlieglR.ShuH. (2013). Parafoveal processing efficiency in rapid automatized naming: A comparison between Chinese normal and dyslexic children. Journal of Experimental Child Psychology, 115(3), 579–589. https://doi.org/10.1016/j.jecp.2013.01.007
74.
YasumuraA.KokuboN.YamamotoH.YasumuraY.NakagawaE.KagaM.HirakiK.InagakiM. (2014). Neurobehavioral and hemodynamic evaluation of Stroop and reverse Stroop interference in children with attention-deficit/hyperactivity disorder. Brain & Development, 36(2), 97–106. https://doi.org/10.1016/j.braindev.2013.01.005
75.
ZhangY.ZhouW. (2022, May). Research on dyslexia detection based on eye tracking [Conference session]. 2022 IEEE 2nd International Conference on Electronic Technology, Communication and Information (ICETCI) (pp. 36–39).IEEE.
76.
ZhouW.XiaZ.GeorgiouG.ShuH. (2022). Shared and unique functional connectivity underpinning rapid naming and character reading in Chinese. Journal of Neurolinguistics, 62, 101052. https://doi.org/10.1016/j.jneuroling.2021.101052
77.
ZieglerJ. C.GoswamiU. (2005). Reading acquisition, developmental dyslexia, and skilled reading across languages: A psycholinguistic grain size theory. Psychological Bulletin, 131(1), 3–29. https://doi.org/10.1037/0033-2909.131.1.3
