Abstract
Objective:
Antidepressants, in particular Atomextine, along with stimulants have demonstrated benefit in the treatment of ADHD. Agomelatine is a new antidepressant with additional affinities to the melatonergic system. As ADHD has been associated with sleep disorders, it is assumed that Agomelatiine might serve as a therapeutic alternative to treat patients with the ADHD refractory to first line medications.
Method:
Ten late adolescents were evaluated in a placebo controlled manner.
Results:
Agomelatine’s effect was superior to that of placebo but appeared to be less than that of first line medications such as methylphenidate.
Conclusion:
Agomelatine may be a useful second line medication for individuals with ADHD, particularly if they suffer from additional sleep disorders.
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