This article is the second in a two-part series that addresses the scientific literature on the contributing factors and preventive strategies for anterior cruciate ligament (ACL) injuries. Part 1, which was presented in a previous edition of Home Health Care Management & Practice (HHCMP), covered contemporary research on the functional anatomy of the knee and precipitating factors to ACL injuries. Part 2, presented here, addresses contemporary trends evident in the peer-reviewed literature on the topic of the rehabilitation of ACL injuries, and it offers suggestions home health care professionals may find useful in the prevention and rehabilitation of this injury.