Deep Venous Thrombosis Caused by Congenital Malformation of the Inferior Vena Cava and Heterozygous Factor V Leiden Presenting as Venous Claudication

Abstract

A case of an 18-year-old man with deep venous thrombosis of the lower limbs caused by hypoplasia of the inferior vena cava in combination with heterozygous factor V Leiden is presented. Both anomalies were found when the patient complained of venous claudication in both thighs. Inferior vena cava malformation is a rare condition and may predispose to the development of deep venous thrombosis. This patient was at an even higher risk for deep venous thrombosis as the inferior vena cava malformation was combined with a hypercoagulable state.

Keywords

hypoplasia inferior vena cava venous thrombosis venous claudication factor V Leiden mutation activated protein C resistance

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