A 57-year-old man of northern Italian and Polish descent with a late-onset, mild form of hereditary factor VII deficiency developed bilateral intracranial subdural hematomas after performing sit-ups while he was in a head-down position on an inversion table. The pertinence of the Valsalva maneuver and increased intracranial venous and intraocular pressure associated with sit-ups and other exercises in the causation of subdural hematomas and other types of intracranial and ocular hemorrhage are discussed in this study.
Hassan HJ, Casalbore P., De Laurenzi A., Petti N., Sinibaldi L., Orlando M.Hereditary factor VII deficiency: report of a case of intracranial hemorrhage . Haemostasis. 1984;14:244-248.
2.
Seaborg BJ, Burns CP, Olson JD, Pennell BJ, Follett KAIntracranial hemorrhage in an adult with factor-VII deficiency. Am J Hematol. 1994;45:98-99.
3.
Doran SE, Henry TR, Bockenstedt PL, Ross DAUncomplicated stereotactic and open neurosurgical procedures in patients with factor VII deficiency. Surg Neurol. 1994;42:79-82.
4.
Chung CP, Hsu HY, Chao AC, Wong WJ, Sheng WY, Hu HHFlow volume in the jugular vein and related hemodynamics in the branches of the jugular vein. Ultrasound Med Biol. 2007 ; 33:500-505.
5.
Dickerman RD , Smith GH, Langham-Roof L., McConathy WJ, East JW, Smith ABIntra-ocular pressure changes during maximal isometric contraction: does this reflect intra-cranial pressure or retinal venous pressure?Neurol Res. 1999;21:243-246.
6.
Pott F., van Lieshout JJ, Ide K., Madsen P., Secher NHMiddle cerebral artery blood velocity during intense static exercise is dominated by a Valsalva maneuver. J Appl Physiol. 2003 ;94:1335-1344.
7.
Uber-Zak LD, Venkatesh YSNeurologic complications of sit-ups associated with the Valsalva maneuver: 2 case reports. Arch Phys Med Rehabil. 2002 ;83: 278-282.
8.
Alaraj AM, Chamoun RB, Dahdaleh NS, Haddad GF, Comair YGSpontaneous subdural haematoma in anabolic steroids dependent weight lifters: reports of two cases and review of literature. Acta Neurochir (Wien). 2005;147:85-87.
9.
Matsuyama T. , Okuchi K., Seki T., Higuchi T., Murao Y.Perimesencephalic nonaneurysmal subarachnoid hemorrhage caused by physical exertion. Neurol Med Chir ( Tokyo). 2006;46:277-281.
10.
Chapman-Davies A., Lazarevic A.Valsalva maculopathy. Clin Exp Optom.2002;85:42-45.
11.
Klatz RM, Goldman RM, Pinchuk BG, Nelson KE, Tarr RSThe effects of gravity inversion procedures on systemic blood pressure, intraocular pressure, and central retinal arterial pressure. J Am Osteopath Assoc. 1983; 82:853-857.
12.
Friberg TR, Sanborn G., Weinreb RNIntraocular and episcleral venous pressure increase during inverted posture . Am J Ophthalmol. 1987;103:523-526.
13.
Weinreb RN, Cook J., Friberg TREffect of inverted body position on intraocular pressure. Am J Ophthalmol. 1984;98:784-787.
14.
Inversion products. Energycenter. http://www.energycenter.com. Accessed July 2, 2007 .
15.
Pros & cons: Inversion traction. Back Designs Inc.http://www.backdesigns.com/AB1921000Store/InversionTraction.asp?SID=1&. Accessed July 2, 2007.
16.
Bernardi F., Liney DL, Patracchini P., et al. Molecular defects in CRM+ factor VII deficiencies: modelling of missense mutations in the catalytic domain of FVII. Br J Haematol. 1994;86:610-618.
17.
Wulff K., Herrmann FHTwenty-two novel mutations of the factor VII gene in factor VII deficiency . Hum Mutat. 2000;15:489-496.
18.
Arbini AA, Bodkin D., Lopaciuk S., Bauer KAMolecular analysis of Polish patients with factor VII deficiency. Blood. 1994;84:2214-2220.
