The presenting signs of osteogenic osteosarcoma are commonly pain, local swelling, local warmth, pathologic fracture, and metastatic disease. Deep venous metastasis of osteoblastic osteosarcoma is most often a postmortem diagnosis. This paper describes the case of a previously healthy 18-year-old woman who presented with dyspnea and lower extremity edema. This is a rare, and to our knowledge, a previously unreported case of right atrial and ventricular tumor thrombus infiltrated with osteoblastic osteosarcoma.
1. Bacci G, Bertoni F, Longhi A, et al. Neoadjuvant chemotherapy for high-grade osteosarcoma. Histologic response to preoperative chemotherapy correlates with histologic subtype of the tumor. Cancer97:3068-3075, 2003
2.
2. Dahlin DC, Coventry MB. Osteogenic sarcoma: A study of six hundred cases. J Bone Joint Surg Am49(l):101-110, 1967
3.
3. Levine AM, Chretien P. Deep venous occlusion as the initial presentation of osteogenic sarcoma of the sacrum. J Bone Joint Surg Am61(5):775-756, 1979
4.
4. McKenna RJ, Schwinn CP, Soong KJ, et al. Sarcomata of osteogenic series. J Bone Joint Surg48:1-26, 1966
5.
5. King CP, Reznek RH. Osteosarcoma metastatic to the kidney with invasion of the inferior vena cava. Br J Radiol65:827-827, 1992
6.
6. McDonald JR, Priestley JT. Malignant tumors of the kidney. Surg Gynecol Obstet77:295-295, 1943
7.
7. Seibert KA, Rettenmier CW, Waller BF, et al. Osteogenic sarcoma metastatic to the heart. Am J Med73:136-141, 1982
8.
8. Kames RJ, Gettman MT, Anderson PM, et al. Primitive neuroectodermal tumor of the kidney with vena caval tumor thrombus. J Urol164 (3 Pt 1):772-772, 2000
