Largely due to a lack of experience, familiarity, and/or confidence, few centers rely on simple fine-needle aspiration biopsy (FNAB) for the diagnosis of sarcomas and related tumors.
Methods
The authors have reviewed their own experience in more than 200 cases of FNAB of bone and soft-tissue tumors, as well as cases reported in the literature.
Results
FNAB has proven to be accurate and useful in 8 consecutive years of clinical experience. No serious complications have occurred.
Conclusions
FNAB is recommended as an integral part of the initial evaluation of amenable orthopaedic tumors, including sarcomas, especially in cases with classic clinical and radiographic findings.
References
1.
KilpatrickS.E., KoplyayP.D., WardW.G.. Epithelioid hemangioendothelioma of bone and soft-tissue: a fine-needle aspiration biopsy study with histologic and immunohistochemical confirmation.Diagn Cytopathol.1998; 19: 38–43.
2.
KilpatrickS.E., WardW.G., CappellariJ.O.. Fine-needle aspiration biopsy of soft-tissue sarcomas: a cytomorphologic analysis with emphasis on histologic subtyping, grading and therapeutic significance.Am J Clin Pathol.1999; 112: 179–188.
3.
NicolK.K., WardW.G., PikeE.J.. Fine-needle aspiration biopsy of gouty tophi: lessons in cost-effective patient management.Diagn Cytopathol.1997; 17: 30–35.
4.
NicolK.K., WardW.G., SavageP.D.. Fine-needle aspiration biopsy of skeletal versus extraskeletal osteosarcoma.Cancer.1998; 84: 176–185.
5.
WardW.G., KilpatrickS.. Fine-needle aspiration biopsy of primary bone tumors.Clin Orthop.2000; 373: 80–87.
6.
DeMayR.M.. Stains. In: DeMayR.M., ed. The Art and Science of Cytopathology. Vol 1. Chicago, Ill: ASCP Press;1996: 14–15.
7.
KilpatrickS.W., CappellariJ.O.P., WardW.G.. Is fine-needle aspiration biopsy a practical alternative to open biopsy for the primary diagnosis of sarcoma? Experience with 140 patients.Am J Clin Pathol.2001; 115: 56–68.
8.
MankinH.J., LangeT.A., SpanierS.S.. The hazards of biopsy in patients with primary bone and soft-tissue tumors.J Bone Joint Surg Am.1982; 64: 1121–1127.
