An Unusual Case of Bilaterally Symmetrical Neuropathic Osteoarthropathy of the Midfoot as a Result of Lyme Disease-Induced Peripheral Neuropathy: A Case Report
Restricted accessResearch articleFirst published online February, 2002
An Unusual Case of Bilaterally Symmetrical Neuropathic Osteoarthropathy of the Midfoot as a Result of Lyme Disease-Induced Peripheral Neuropathy: A Case Report
The first known report of a patient with Lyme Disease-induced peripheral neuropathy resulting in bilaterally symmetrical “Charcot” changes of the midfoot is reported. An extensive review of the literature failed to produce any known cases of neuropathic osteoarthropathy that would be linked directly or indirectly with Lyme Disease-Induced peripheral neuropathy. The relationship between Lyme Disease, the secondary neurologic manifestations caused by the infection, and neuropathic osteoarthropathy are discussed.
StechenbergBW: Lyme Disease: the latest great imitator. Pediatr. Infect. Dis., 7 (6): 402–409, 1988.
6.
FinkelMF: Lyme Disease and Its Neurologic Complications. Arch. Neurol.45: 99–104, 1988.
7.
HalperinJJLittleBWCoylePKDattwylerRJ: Lyme Disease: Cause of a treatable peripheral neuropathy. Neurology37: 1700–1716, 1987.
8.
BalmelliT.PiffarettiJ. C.: Association between different clinical manifestations of Lyme Disease and different species of Borrelia Burgdorferi sensu lato. Institute Pasteur/Elsevier.146: 329–340, 1995.
9.
HalperinJJPassHJAnandAK.: Nervous System Abnormalities in Lyme Disease. Ann. NY Acad. Sci.539: 24–34, 1988.
10.
AnandN.LevineD.BurkeS.BansalM.: Neuropathic Spinal Arthropathy in Charcot-Marie-Tooth Disease. J Bone Joint Surg.79-a (8): 1235–1239, 1997.
11.
KovacsS. SlowmanBraunsteinE.BrandtK.: Rapidly Progressive Charcot Arthropathy Following Minor Joint Trauma in Patients with Diabetic Neuropathy. Arthritis Rheum.33 (3): 412–417, 1990.
12.
SequeriaW.: The neuropathic joint. Clin. Exp. Rheumatol.12: 325–337, 1994.
13.
GuisS.PellissierJ.ArniaudD..: Healing of Charcot's Joint by Pamidronate Infusion. J. Rheumatol.26: 1843–1845, 1999.
14.
ChappelR.WillemsJ.MartinJJ: Charcot in Idiopathic Sensorimotor Neuropathy. Clin. Rheumatol.19: 153–155, 2000.
15.
DarstM.WeaverT.ZangwillB.: Charcot's Joint Following Keller Arthroplasty—A case report. J Am. Podiatr. Med. Assoc.88 (3): 140–143, 1998.