Primary cystic neoplasms in the liver with ovarian type stroma typically represent mucinous cystic neoplasms. These tumors contain a cuboidal to columnar epithelium with variably mucinous cytoplasm. To the best of our knowledge, there are no reports of primary hepatic cystic neoplasms with ovarian-type stroma and ciliated epithelial lining. We describe a case of a 53-year-old woman with a history of a multicystic mass in the right hepatic lobe that did not communicate with the biliary tree. The tumor contained multiple cysts with large papillae lined with ciliated Mullerian epithelium and subepithelial ovarian-type stroma.
DevaneyKGoodmanZDIshakKG. Hepatobiliary cystadenoma and cystadenocarcinoma. A light microscopic and immunohistochemical study of 70 patients. Am J Surg Pathol. 1994;18(11):1078‐1091.
2.
ZenYPedicaFPatchaVR, et al.Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with intraductal papillary neoplasms of the bile duct. Mod Pathol. 2011;24(8):1079‐1089.
3.
SafariMTShahrokhSMiriMBForoughiFSadeghiA. Biliary mucinous cystic neoplasm: a case report and review of the literature. Gastroenterol Hepatol Bed Bench. 2016;9(Suppl1):S88‐S92.
4.
BishopKCPerrinoCMRuzinovaMBBruntEM. Ciliated hepatic foregut cyst: a report of 6 cases and a review of the English literature. Diagn Pathol. 2015;10(1):81.
5.
IshakKGWillisGWCumminsSDBullockAA. Biliary cystadenoma and cystadenocarcinoma: report of 14 cases and review of the literature. Cancer. 1977;39(1):322‐338.
6.
QuigleyBReidMDPehlivanogluB, et al.Hepatobiliary mucinous cystic neoplasms with ovarian type stroma (so-called “hepatobiliary cystadenoma/cystadenocarcinoma”): clinicopathologic analysis of 36 cases illustrates rarity of carcinomatous change. Am J Surg Pathol. 2018;42(1):95‐102.
7.
FarrellJJ. Prevalence, diagnosis and management of pancreatic cystic neoplasms: current Status and future directions. Gut Liver. 2015;9(5):571‐589.
8.
YoonMHYoonJWHanBH. Mucinous cystadenoma of the liver with ovarian-like stroma: the need for complete resection. J Korean Surg Soc. 2011;81(Suppl 1):S51‐S54.
9.
Van TreeckBJLotfallaMCzeczokTW, et al.Molecular and immunohistochemical analysis of mucinous cystic neoplasm of the liver. Am J Clin Pathol. 2020;154(6):837‐847.
10.
CirisMErhanYZekiogluOBayramogluH. Inhibin alpha and beta expression in ovarian stromal tumors and their histological equivalences. Acta Obstet Gynecol Scand. 2004;83(5):491‐496.
11.
KorogluMAkhanOAkpinarEOtoAGumusB. Biliary cystadenoma and cystadenocarcinoma: two rare cystic liver lesions. JBR-BTR. 2006;89(5):261‐263.
12.
FujitaKOgawaCSakoTUtsumiFInadaKIShibataK. A case of ovarian serous cystadenofibroma with scattered lesions in pelvic cavity, like malignant disseminations. J Obstet Gynaecol Res. 2021;47(12):4496‐4501.
13.
HinsonSASilvaEGPintoK. Ovarian serous cystadenofibromas associated with a low-grade serous carcinoma of the peritoneum. Ann Diagn Pathol. 2013;17(3):302‐304.
14.
SinghaniaNJanakiramanNCoslettDAhmadN. Endosalpingiosis in conjunction with ovarian serous cystadenoma mimicking metastatic ovarian malignancy. Am J Case Rep. . 2014;15:361‐363.
15.
ClementPBYoungRH. Florid cystic endosalpingiosis with tumor-like manifestations: a report of four cases including the first reported cases of transmural endosalpingiosis of the uterus. Am J Surg Pathol. 1999;23(2):166‐175.
16.
WangDYangQWangHLiuC. Malignant transformation of hepatic endometriosis: a case report and literature review. BMC Womens Health. 2021;21(1):249.
17.
JiWWuJChengJDiW. Serous adenocarcinoma arising from endometriosis in cesarean section abdominal wall scar: a case report and literature review. Int J Clin Exp Pathol. 2017;10(7):7534‐7541.
18.
NuovoMBayaniEGeroldTLeongMMirR. Endometrioid cystadenofibroma developing in juxtahepatic endometriosis. Int J Surg Pathol.2016;6(2):109‐112.
19.
CovellJLCarryJBFeldmanPS. Peritoneal washings in ovarian tumors. Potential sources of error in cytologic diagnosis. Acta Cytol. 1985;29(3):310‐316.
20.
Abou-FoulAKMadiMBuryDMerrittA. Metastasising pleomorphic salivary gland adenoma presenting as synchronous pulmonary and hepatic metastases. BMJ Case Rep. 2014;2014.
21.
SinghalAShragoSSLiSFHuangYKohliV. A hepatic metastasis from pleomorphic adenoma of salivary gland: an unusual presentation. Hepatogastroenterology. Mar. Apr 2010;57(98):330‐333.
FangSHDongDJZhangSZ. Imaging features of ciliated hepatic foregut cyst. World J Gastroenterol. 2005;11(27):4287‐4289.
24.
CottreauJCostaAWalshMArnasonT. Ciliated foregut cyst of the common hepatic duct: an unusual mimic of a type II choledochal cyst. Int J Surg Pathol. 2016;24(7):644‐647.
