This case was presented to acquaint the reader with (1) manifestations of acute brain syndrome, (2) clinical situations frequently associated with acute brain syndrome, and (3) drug frequently used in the geriatric patient that that have been associated with acute brain syndrome.
AgateJ.: The Practice of Geriatrics, 2nd Ed. Charles C. Thomas, Springfield, Illinois, 1970. pg 361–365.
2.
AitaJ. A.: The Neurological Phenomena of Potassium Disorders, Nebraska State Med. J.51: 373, 1966.
3.
BlackwellB.: The Drug Defaulter, Clin. Pharmacol. Ther.13: 841, 1972.
4.
BurnellG. M., and FosterT. A.: Psychosis With Low Sodium Syndrome, Amer. J. Psychiat.128: 1313, 1972.
5.
BurnellJ. M.: The Effect in Humans of Extracellular pH Changes on the Relationship Between Serum Potassium Concentration and Intracellular Potassium, J. Clin. Invest.35: 935, 1956.
6.
ButlerR. N.: Clinical Psychiatry in Late Life. In: Clinical Geriatrics, RossmanI. (ed). J. B. Lippincott, Philadelphia, 1971. pg 443–444.
7.
CampionD. S., AriasJ. M., and CarterN. W.: Rhabdomyolysis and Myoglobinuria Association With Hypokalemia of Renal Tubular Acidosis, J. Amer. Med. Assoc.220: 967, 1972.
8.
DrutzD. J., FanJ. H., and TaiT. Y.: Hypokalemia Rhabdomyolysis and Myoglobinuria Following Amphotericin B Therapy, J. Amer. Med. Assoc.211: 824, 1970.
9.
DundeeJ. W., IsaacM., DavisE. A., and SheridanB.: Effects of Rapid Infusion of Ethanol on Some Factors Controlling Blood Sugar Levels in Man, Quart. J. Study Alc.33: 722, 1972.
10.
EpsteinL. J., and SimonA.: Organic Brain Syndrome in the Elderly, Geriatrics22: 145, 1967.
11.
EwyG. A., KapadiaG. G., YaoL., LullinM., and MarcusF. I.: Digoxin Metabolism in the Elderly, Circulation39: 449, 1969.
12.
FinestoneA. J., and BiancoF. J.: Organic Brain Syndrome, Amer. Family Phys.6: 74, 1972.
13.
FlearC. T. G.: Serum Potassium Levels as an Index of Body Content, Lancet272: 458, 1957.
14.
FlintF. J., and RichardsS. M.: Organic Basis of Confusional States in the Elderly, Brit. Med. J.2: 1537, 1956.
15.
GarrowJ. S.: Loss of Brain Potassium in Kwashiorkor, Lancet2: 643, 1967.
16.
GlaserG. H.: Neurological Symptoms With Electrolyte and Water Imbalance, Postgrad. Med.50: 170, 1971.
17.
GoldfarbA. I.: Integrated Psychiatric Services For the Aged, Bull N.Y. Acad. Med.49: 1070, 1973.
18.
GoldmanR.: Decline in Organ Function With Aging, In: Clinical Geriatrics, RossmanI. (ed). J. B. Lippincott, Philadelphia, 1971. pg 24–27.
19.
GouldD. B., SorrellM. R., and LuparielloA. D.: Barium Sulfide Poisoning, Some Factors Contributing to Survival, Arch. Intern. Med.132: 891, 1973.
20.
GrossE. G., DexterJ. D., and RothR. G.: Hypokalemic Myopathy with Myoglobinuria Associated With Licorice Ingestion, N. Engl. J. Med.274: 602, 1966.
21.
HodkinsonH. M.: Mental Impairment in the Elderly, J. Roy. Coll. Physicians, (London)7: 305, 1973.
22.
HoffbrandB. I., and StewardJ.D.M.: Carbenicillin and Hypokalemia, Brit Med. J.4: 746, 1970.
23.
HurwitzN., and WadeO. L.: Intensive Hospital Monitoring of Adverse Reactions to Drugs, Brit. Med. J.1: 531, 1969.
24.
JudgeT. G.: Hypokalemia in the Elderly, Genont. Clin.10: 102, 1968.
25.
KahnR. L., GoldfarbA. I., PollackM., and PeckA.: Brief Objective Measures For the Determination of Mental Status in the Aged, Amer. J. Psychiat.117: 326, 1960.
26.
KahnR. L.: Psychological Aspects of Aging. In Clinical Geriatrics, RossmanI. (ed). J. B. Lippincott, Philadelphia, 1971. pg 110–112.
27.
KayD. W. K., and RothM.: Physical Accompaniments of Mental Disorders in Old Age, Lancet2: 740, 1955.
28.
Anon: Drugs and the Elderly Mind, Lancet2: 126, 1972.
29.
LawsonD. H., MurrayR. M., ParkerJ. L. W., and HayG.: Hypokalemia in Megaloblastic Anemias, Lancet1: 588, 1970.
30.
Leading Article: Alcoholic Hypoglycemia, Brit. Med. J.1: 463, 1968.
31.
LearoydB. M.: Psychotropic Drugs and the Elderly Patient, Med. J. Aust.1: 1131, 1972.
32.
LiebmanJ., and EdelmonI. S.: Interrelations of Plasma Potassium Concentration, Plasma Sodium Concentration, Arterial pH, and Total Exchangeable Potassium, J. Clin. Invest.38: 2176, 1959.
33.
LiblowL. S.: Pseudo-Senility, Acute and Reversible Organic Brain Syndromes, J. Amer. Geriatrics Soc.21: 112, 1973.
34.
LowensteinJ.: Hypokalemia and Hyperkalemia, Med. Clin. N. Amer.57: 1435, 1973.
35.
LowmanR. M.: The Potassium Depletion States and Postoperative Ileus, Radiology98: 691, 1971.
36.
MarondeR. F., MilgromM., and DickeyJ. M.: Potassium Loss With Thiazide Therapy, Amer. Heart J.78: 16, 1969.
37.
McCarronM. M., and McCormickR. A.: Acute Organic Disorder Accompanied by Mental Symptoms, Department of Mental Hygiene, Sacramento, California, 1967. pg i–iii, 33–36.
38.
MeisterF.: Hypertension with Nephrosclerosis, Drug Intell. Clin. Pharm.7: 208, 1973.
39.
MitchellW., and FeldmanF.: Neuropsychiatric Aspects of Hypokalemia, Canad. Med. Assoc. J.98: 49, 1968.
40.
MooreF. D.: The Body Cell Mass and Its Supporting Environment, W. B. Saunders Co., Philadelphia, 1963. pg 21–22, 28, 87, 100.
41.
O'TooleJ. F., and PatelA. N.: Cerebral Atherosclerosis. In: Cerebrovascular Disorders, O'TooleJ. F. (ed). McGraw-Hill, New York, 1967. pg 123.
OwenE. E., and VernerJ. U.Jr.: Renal Tubular Acidosis With Muscle Paralysis and Hypokalemia, Amer. J. Med.28: 9, 1960.
44.
PathyM.S.: Clinical Presentation of Myocardial Infarction in the Elderly, Brit. Heart J.29: 190, 1967.
45.
PriddleW. W., LiuS. F., and BreithauptD. J.: Management of Hypertension, Further Sodium and Potassium Studies, J. Amer. Geriatrics Soc.18: 861, 1970.
46.
ProckopL. D., Disorders of Cerebrospinal Fluid and Brain Extracellular Fluid. In: Biology of Brain Dysfunction, GaullG. E. (ed). Plenum Press, New York, 1973. pg 252.
47.
RemenchikA. P., MillerC., TalsoP. J., and WilloughbyE. O.: Depletion of Body Potassium by Diuretics, Circulation33: 796, 1966.
48.
RifkinH., and RossH.: Diabetes in the Elderly. In: Clinical Geriatrics, RossmanI. (ed). J. B. Lippincott, Philadelphia, 1971. pg 402.
49.
RossmanI.: The Anatomy of Aging. In: Clinical Geriatrics, RossmanI. (ed). J. B. Lippincott, Philadelphia, 1971. pg 13–16.
50.
RozaO., and BermanL. B.: The Pathophysiology of Barium, Hypokalemia and Cardiovascular Effects, J. Pharmacol. Exp. Ther.177: 433, 1971.
51.
SagildU.: Total Exchangeable Potassium in Normal Subjects With Special Reference to Changes in Age, Scand. J. Clin. Lab. Invest.8: 44, 1956.
52.
SchulzeB.: Metabolic Complications of Hydrochlorothiazide Therapy, Drug Intell. Clin. Pharm.7: 501, 1973.
53.
SchwartzD., WangM., ZeitzL., and GossM. E. W.: Medication Errors Made by Elderly, Chronically Ill Patients, Amer J. Pub. Health52: 2018, 1962.
54.
SchwartzW. B., and RelmanA. S.: Metabolic and Renal Studies in Chronic Potassium Depletion Resulting From Overuse of Laxatives, J. Clin. Invest.32: 258, 1953.
55.
SchwartzW. B.: Pathogenesis and Replacement of Diuretic-Induced Potassium and Chloride Loss, Ann. N.Y. Acad. Sci.139: 506, 1966.
56.
SchwartzW. B., van Ypersele de StrihouC., and KassirerJ. P.: Medical Progress, Role of Anions in Metabolic Alkalosis and Potassium Deficiency, N. Engl. J. Med.279: 630, 1968.
57.
SeksoM., CabrijanT., BanovacK., and BirticK.: Primary Aldosteronism With Hypopotassemic Coma, Endokrinologie59: 348, 1972.
58.
ShaderR. I., and GreenblattD. J.: Belladonna Alkaloids and Synthetic Anticholinergics, Uses and Toxicity. In: Psychiatric Complications of Medical Drugs, ShaderR. (ed). Raven Press, New York, 1972. pg 103–147.
59.
ShaderR. I. (ed): Psychiatric Complications of Medical Drugs, Raven Press, New York, 1972.
60.
Siersback-NielsenK., HansenJ. M., KampmannJ., and KristensenM.: Rapid Evaluation of Creatinine Clearance, Lancet1: 1133, 1971.
61.
StaffurthJ. S.: The Total Exchangeable Potassium in Patients with Hypokalemia, Postgrad. Med. J.40: 4, 1964.
62.
StangeR. R.: Comparative Study of Trihexyphenidyl (Artane) and Orphenadrine (Disipal) in Treatment of Geriatric Parkinsonism, J. Amer. Geriat. Soc.13: 756, 1965.
63.
StephensD. A.: Psychotoxic Effects of Benzhexol Hydrochloride (Artane), Brit. J. Psychiat.113: 213, 1967.
64.
StewartR. B., and CluffL. E.: A Review of Medication Errors and Compliance in Ambulant Patients, Clin. Pharmacol. Ther.13: 463, 1972.
65.
SurawiczB.: The Role of Potassium in Cardiovascular Therapy, Med. Clin. N. Amer.52: 1103, 1968.
66.
TourtelloteC., and HirstA.: Hypokalemia Muscle Weakness and Myoglobinuria Due to Licorice Ingestion, Calif. Med.113: 51, 1970.
67.
VerwoerdtA.: Clinical Geropsychiatry. In: Working with Older People. Vol. IV: Clinical Aspects of Aging, ChinnA. B. (ed). Washington, D. C.: Government Printing Office, 1971, page 67.
68.
WeinerM., and EpsteinF. H.: Signs and Symptoms of Electrolyte Disorders, Yale J. Biol. & Med.43: 16, 1970.
69.
WeissmanP. N., ShenkmanL., and GregermanR. I.: Chlorpropamide Hyponatremia, Drug-Induced Inappropriate ADH Activity, N. Engl. J. Med.284: 65, 1971.
70.
ZivinI., and ShalowitzM. D.: Acute Toxic Reaction to Prolonged Glutethimide Administration, N. Engl. J. Med.266: 496, 1962.
