There have been repeated outbreaks of leptospirosis reported all over the world. Being one of the largest cities in the world, Hong Kong is no exception. We report a local case involved in an outbreak of the disease with a typical route of acquisition but rare complications. A brief account on the epidemiology of both Hong Kong and Southern China is given. Discussions on the pathophysiology of the disease and its complications are also presented.
Centers for Disease Control and Prevention.Update: leptospirosis and unexplained acute febrile illness among athletes participating in triathlons–Illinois and Wisconsin, 1998.MMWR Morb Mortal Wkly Rep1998;47(32): 673–6.
5.
Centers for Disease Control and Prevention.Outbreak of acute febrile illness among participants in EcoChallenge Sabah 2000-Malaysia, 2000.MMWR Morb Mortal Wkly Rep2000; 49: 816–7.
6.
PappachanM.J., SheelaM., AravindanK.P.Relation of rainfall pattern and epidemic leptospirosis in the Indian state of Kerala.J Epidemiol Community Health2004; 58(12): 1054.
7.
SumM.A local sporadic case of human leptospirosis. Public Health and Epidemiology Bulletin, Department of Health, Hong Kong.2002 Feb; Volume 11, Number 1.
8.
ChoiK.W.Leptospirosis.Bulletin of the Hong Kong Society for Infectious Diseases2001; 5(4): 29–30.
9.
MerienF., BarantonG., PerolatP.Invasion of Vero cells and induction of apoptosis in macrophages by pathogenic Leptospira interrogans are correlated with virulence.Infect Immun1997; 65(2): 729–38.
10.
GuarnerJ., ShiehW.J., MorganJ., BraggS.L., BajaniM.D., TapperoJ.W.Leptospirosis mimicking acute cholecystitis among athletes participating in a triathlon.Hum Pathol2001; 32(7): 750–2.
11.
ParkerM.M., ShelhamerJ.H., NatansonC., AllingD.W., ParrilloJ.E.Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis.Crit Care Med1987; 15(10): 923–9.
12.
StanchinaM.L., LevyM.M.Vasoactive drug use in septic shock.Semin Respir Crit Care Med2004; 25(6): 673–81.
13.
GuidugliF., CastroA.A., AtallahA.N. Antibiotics for leptospirosis. Cochrane Hepato-Biliary Group. Cochrane Database of Systematic Reviews. 1, 2005.
14.
PanaphutT., DomrongkitchaipornS., VibhagoolA., ThinkamropB., SusaengratW.Ceftriaxone compared with sodium penicillin g for treatment of severe leptospirosis.Clin Infect Dis2003; 36(12): 1507–13.