ZnO nanostructures were synthesized via a hydrothermal method using four different zinc precursors (zinc acetate, zinc chloride, zinc nitrate, and zinc sulfate) to systematically investigate the influence of precursor chemistry on their structural, morphological, and vibrational properties. X-ray diffraction analysis confirmed the formation of the hexagonal wurtzite phase in all samples, with significant variations in crystallinity and lattice constants attributable to the nature of the precursor anions. ZnO synthesized from zinc chloride exhibited the highest degree of crystallinity, whereas the zinc sulfate–derived sample showed pronounced defect formation. Scanning electron microscopy revealed a strong dependence of morphology on the precursor type, yielding well-defined nanorod architectures for zinc acetate, nitrate, and chloride, while zinc sulfate produced irregular and highly agglomerated structures. Energy-dispersive X-ray analysis verified the elemental purity of the samples, with Zn/O ratios indicating varying defect concentrations. Further insights from FT-IR and Raman spectroscopy highlighted differences in surface functional groups, lattice order, and defect states. Overall, these results demonstrate that precursor selection plays a critical role in tailoring the structural quality and defect characteristics of ZnO nanostructures, providing an effective strategy for optimizing their properties for targeted applications.
Abd AlsahebRRahimnejadMAtyiaM. Exploring preparation of zinc oxide nanoparticles synthesis mechanisms and applications: a comprehensive review. Int J Eng2025; 38: 1223–1244.
2.
BarbosaHPAraújoDAGPradela-FilhoLA, et al.Zinc oxide as a multifunctional material: from biomedical applications to energy conversion and electrochemical sensing. In: Metal and metal oxides for energy and electronics. Cham, Switzerland: Springer, 2020, pp.251–305.
3.
BhakyalathaMSathishSSekharK, et al.Zno nanostructures for biosensing applications: recent advances, challenges, and future perspectives. Microchem J2025; 213: 113893.
4.
RahaSAhmaruzzamanM. Zno nanostructured materials and their potential applications: progress, challenges and perspectives. Nanoscale Adv2022; 4: 1868–1925.
5.
BedhoucheFSoualahADjouadiD, et al.Photoactivity properties of ZnO-doped erbium: synthesis, characterization, and EPR spectroscopy investigation. Water Air Soil Pollut2024; 235: 6.
6.
ChangJSSaintCPChowCW, et al.Recent innovations in engineering Zinc Oxide (ZnO) nanostructures for water and wastewater treatment: pushing the boundaries of multifunctional photocatalytic and advanced biotechnological applications. Int Mater Rev2024; 69: 337–379.
7.
LebakaVRRaviPReddyMC, et al.Zinc oxide nanoparticles in modern science and technology: multifunctional roles in healthcare, environmental remediation, and industry. Nanomaterials2025; 15: 54.
8.
BakryMIsmailWAbdelfatahM, et al.Low-cost fabrication methods of ZnO nanorods and their physical and photoelectrochemical properties for optoelectronic applications. Sci Rep2024; 14: 23788.
9.
BedhoucheFDjouadiDSoualahA, et al.Effects of supercritical mediums on structural, optical and photocatalytic properties of pure and Er-doped ZnO nanostructures. Chem Africa2025; 8: 1–13.
10.
LalMSharmaPRamC. Optical, structural properties and photocatalytic potential of Nd-ZnO nanoparticles synthesized by hydrothermal method. Results Optics2023; 10: 100371.
11.
Ait AbdelouhabZDjouadiDCheloucheA, et al.Structural and morphological characterizations of pure and Ce-doped ZnO nanorods hydrothermally synthesized with different caustic bases. Mater Sci Poland2020; 38: 228–235.
12.
AkterMFaisalMASinghAK, et al.Hydrophilic ionic liquid assisted hydrothermal synthesis of ZnO nanostructures with controllable morphology. RSC Adv2023; 13: 17775–17786.
13.
MohamedRAnuarMSA. Structural and electrochemical behaviors of ZnO structure: effect of different zinc precursor molarity. Condensed Matter2022; 7: 71.
14.
Ait AbdelouhabZDjouadiDCheloucheA, et al.Effects of precursors and caustic bases on structural and vibrational properties of ZnO nanostructures elaborated by hydrothermal method. Solid State Sci2019; 89: 93–99.
15.
GatouM-ALagopatiNVagenaI-A, et al.Zno nanoparticles from different precursors and their photocatalytic potential for biomedical use. Nanomaterials2023; 13: 22.
16.
LeiteRRColomboRJúniorFEB, et al.Precursor effect on the hydrothermal synthesis of pure ZnO nanostructures and enhanced photocatalytic performance for norfloxacin degradation. Chem Eng J2024; 496: 154374.
17.
SongpanitMBoonyarattanakalinKPecharapaW, et al.Zno nanostructures synthesized by one-step sol-gel process using different zinc precursors. J Metals, Mater Minerals2024; 34: 1968–1968.
18.
SheikhiSAliannezhadiMTehraniFS. Effect of precursor material, pH, and aging on ZnO nanoparticles synthesized by one-step sol–gel method for photodynamic and photocatalytic applications. European Phys J Plus2022; 137: 60.
19.
ChandanaMLavanyaDMalleshappaJ, et al.Effect of precursors on ZnO nanoparticles to enhance the level-III ridge details of LFPs and anti-counterfeiting applications. Mater Sci Semicond Process2023; 167: 107749.
20.
Limon-RochaIGuzmán-GonzálezCAAnaya-EsparzaLM, et al.Effect of the precursor on the synthesis of ZnO and its photocatalytic activity. Inorganics2022; 10: 16.
21.
SundarabharathiLPonnammaDParangusanH, et al.Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles. SN Appl Sci2020; 2: 94.
22.
HossainMZNayemSAAlamMS, et al.Hydrothermal ZnO nanomaterials: tailored properties and infinite possibilities. Nanomaterials2025; 15: 09.
23.
WangRZhuJYangM, et al.Simultaneous manipulation of anions and water molecules by lewis acid–base for highly stable Zn anodes. Angew Chem2025; 137: e202501327.
24.
KuzmanovićBVujkovićMMamulaBP, et al.Cation-induced structural/morphological control of ZnO under alkaline hydrothermal conditions: Influence on photocatalytic activity. Ceram Int2025; 51: 59897–59810.
25.
Zhang and YanagisawaK. Hydrothermal synthesis of zinc hydroxide chloride sheets and their conversion to ZnO. Chem Mater2007; 19: 2329–2334.
26.
LongTYinSTakabatakeK, et al.Synthesis and characterization of ZnO nanorods and nanodisks from zinc chloride aqueous solution. Nanoscale Res Lett2009; 4: 47.
27.
PourrahimiAMLiuDPallonLK, et al.Water-based synthesis and cleaning methods for high purity ZnO nanoparticles–comparing acetate, chloride, sulphate and nitrate zinc salt precursors. RSC Adv2014; 4: 35568–35577.
28.
AlvesMM. Interplay between zinc surface functionalization and degradation behavior in targeted implant applications. Surface Interfaces2025: 105776. doi:10.1016/j.surfin.2025.105776
29.
RenFXinRGeX, et al.Characterization and structural analysis of zinc-substituted hydroxyapatites. Acta Biomater2009; 5: 3141–3149.
30.
AbdelouhabZADjouadiDCheloucheA, et al.Structural, morphological and Raman scattering studies of pure and Ce-doped ZnO nanostructures elaborated by hydrothermal route using nonorganic precursor. J Sol-Gel Sci Technol2020; 95: 136–145.
31.
BarrettCSCSBTBM. Structure of metals. Crystallographic methods, principles and data. 1980.
32.
AminGAsifMZainelabdinA, et al.Influence of pH, precursor concentration, growth time, and temperature on the morphology of ZnO nanostructures grown by the hydrothermal method. J Nanomater2011; 2011: 269692.
33.
AmirthavalliCManikandanAPrinceA. Effect of zinc precursor ratio on morphology and luminescent properties of ZnO nanoparticles synthesized in CTAB medium. Ceram Int2018; 44: 15290–15297.
34.
OzelETuncoluIGAciksariC, et al.Effect of precursor type on zinc oxide formation and morphology development during hydrothermal synthesis. Hittite J Sci Eng2016; 3: 73–80.
35.
ThoratAAhireBKateA, et al.Synthesis, characterization of ZnO nanoparticles and the impact of changing the proportion of precursor on their morphology, average formation, and its antimicrobial activity. Orient J Chem2025; 41: 178–184.
36.
ZubairNAl-OqailiRMSYousafMJ, et al.Morphology dependent antibacterial activity of zinc oxide nanoparticles against clinically relevant bacteria. Sci Rep2025; 15: 45186.
37.
AwwadAMAlbissBAhmadAL. Green synthesis, characterization and optical properties of zinc oxide nanosheets using Olea europea leaf extract. Adv Mater Lett2014; 5: 520–524.
38.
GayenRDasSDaluiS, et al.Zinc magnesium oxide nanofibers on glass substrate by solution growth technique. J Cryst Growth2008; 310: 4073–4080.
39.
SafawoTSandeepBPolaS, et al.Synthesis and characterization of zinc oxide nanoparticles using tuber extract of anchote (Coccinia abyssinica (Lam.) Cong.) for antimicrobial and antioxidant activity assessment. OpenNano2018; 3: 56–63.
40.
MalakarBMiahATKalitaC, et al.Structural evaluation and photocatalytic performance of chemically synthesised ZnO nanoparticles. Chem Sci2015; 4: 788–798.
41.
SerranoJManjónFRomeroA, et al.The phonon dispersion of wurtzite-ZnO revisited. Phys Stat Solidi (b)2007; 244: 1478–1482.
42.
RussoVGhidelliMGondoniP, et al.Multi-wavelength Raman scattering of nanostructured Al-doped zinc oxide. J Appl Phys2014; 115: 073508.
43.
SanderTEisermannSMeyerB, et al.Raman Tensor elements of wurtzite ZnO. Phys Rev B—Condensed Matter Mater Phys2012; 85: 165208.
44.
GuoSDuZDaiS. Analysis of Raman modes in Mn-doped ZnO nanocrystals. Phys Status Solidi (b)2009; 246: 2329–2332.
45.
YahiaSBZnaidiLKanaevA, et al.Raman Study of oriented ZnO thin films deposited by sol–gel method. Spectrochim Acta, Part A2008; 71: 1234–1238.
46.
CuscóRAlarcón-LladóEIbáñezJ, et al.Temperature dependence of Raman scattering in ZnO. Phys Rev B—Condens Matt Mater Phys2007; 75: 165202.
47.
ChengA-JTzengYXuH, et al.Raman analysis of longitudinal optical phonon-plasmon coupled modes of aligned ZnO nanorods. J Appl Phys2009; 105: 073104.
48.
SreenivasKKumarSChoudharyJ, et al.Growth of zinc oxide nanostructures. Pramana2005; 65: 809–814.
49.
Soosen SamuelMKoshyJChandranA, et al.Optical phonon confinement in ZnO nanorods and nanotubes. Indian J Pure Appl Phys2010; 48: 703–708.
