Abstract
Background
Near infrared spectroscopy (NIRS) measures regional tissue oxygen saturation (rSO2) and is used in Western neonatal intensive care units (ICUs) to monitor early organ dysfunction, but its effectiveness on Indian neonates is not well documented.
Objectives
We evaluated cerebral, splanchnic regional oxygen saturation (CrSO2 and SrSO2) and fractional tissue oxygen extraction (FTOE) in healthy Indian neonates using an U.S. Food and Drug Administration (FDA)-approved NIRS device.
Study Design
A prospective observational study.
Participants
Healthy neonates above 34 weeks gestation born at private tertiary hospital were studied. The study excluded babies with congenital anomalies, low APGAR scores, and babies requiring respiratory support.
Intervention
An INVOSTM 5100 C Regional Oximeter with two sensors were attached to the baby’s forehead and infraumbilical area for an hour following the initial transition period of the first ten minutes of life.
Results
Mean CrSO2 was significantly higher than SrSO2 by 10.87, p < 0.0001. Late preterm and low birth weight babies had higher CrSO2, while late preterm infants had lower SrSO2 than term infants. There was no significant SrSO2 difference based on weight. Regional saturations and calculated FTOE’s at 15, 30, 45, and 60 minutes were reported.
Outcomes
Findings indicate similar rSO2 and FTOE ranges as described in literature.
Conclusion
CrSO2 was higher than SrSO2, with notable differences among late preterm and lower-weight infants compared to term infants. Larger studies involving Indian neonates are warranted.
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