A woman’s life undergoes several physiological changes during pregnancy, which have an impact on their health-related quality of life (HRQoL). Therefore, evaluating QoL during pregnancy could support the implementation of innovative practices for improving outcomes. The main objective of this study is to evaluate and identify the predictors associated with HRQoL during the trimesters of pregnancy. A cross-sectional study was carried out across slum areas of Hyderabad City on a sample of 267 lactating mothers having less than 6-month-old infants during August to October 2022. HRQoL was measured through the World Health Organization Quality of Life–Brief Version (WHOQOL-BREF) instrument, and questionnaires on maternal and socio-demographic variables were included. The analysis was performed using SPSS version 21. Descriptive statistics, probability and χ2 analysis were used to identify associated factors and Cronbach’s α was used to assess the reliability of questionnaires. This study reveals that socio-economic predictors associated with QoL were community, source of water, type of house, debt and foods taken. Age at marriage, having diabetes or blood pressure, economic status, education, multiparous and doing exercise were associated with HRQoL during pregnancy. This study underscores that modifiable factors would improve QoL, whereas mean values of all domains of HRQoL are lowest during the third trimester, suggesting more policies and implementation of actions for better outcomes.
AbediP., JorfiM., & AfshariP. (2015). Evaluation of the health promotion lifestyle and its related factors in reproductive aged women in Ahvaz, Iran. Journal of Community Health, 9(1), 68–74. https://chj.rums.ac.ir/article_45748.html
2.
Amiel-TisonC., CabrolD., DenverR., JarreauP.-H., PapiernikE., & PiazzaP. V. (2004). Fetal adaptation to stress: Part, II. Evolutionary aspects; stress-induced hippocampal damage; long-term effects on behavior; consequences on adult health. Early Human Development, 78(2), 81–94. https://doi.org/10.1016/j.earlhumdev.2004.03.007
3.
AmoozegarF., & PringsheimT. (2009). Rizatriptan for the acute treatment of migraine: Consistency, preference, satisfaction, and quality of life. Patient Prefer Adherence, 3(3), 251–258. https://doi.org/10.2147/ppa.s6152
4.
BaleT. L. (2005). Is mom too sensitive? Impact of maternal stress during gestation. Frontiers in Neuroendocrinology, 26(1), 41–49. https://doi.org/10.1016/j.yfrne.2005.03.002
5.
BarkerD. J. (1991). The intrauterine origins of cardiovascular and obstructive lung disease in adult life. The Marc Daniels Lecture 1990. Journal of the Royal College of Physicians London, 25(2), 129–133. https://pubmed.ncbi.nlm.nih.gov/2066923/
6.
BeydounH., & SaftlasA. F. (2008). Physical and mental health outcomes of prenatal maternal stress in human and animal studies: A review of recent evidence. Paediatric and Perinatal Epidemiology, 22(5), 438–466. https://doi.org/10.1111/j.1365-3016.2008.00951.x
7.
BoutibA., ChergaouiS., MarfakA., HilaliA., & Youlyouz-MarfakI. (2022). Quality of life during pregnancy from 2011 to 2021: Systematic review. International Journal of Women’s Health, 14, 975–1005. https://doi.org/10.2147/IJWH.S361643
8.
CalouC. G. P., de OliveiraM. F., CarvalhoF. H. C., SoaresP. R. A. L., BezerraR. A., de LimaS. K. M., AntezanaF. J., de Souza AquinoP., CastroR. C. M. B., & PinheiroA. K. B. (2018). Maternal predictors related to quality of life in pregnant women in the Northeast of Brazil. Health and Quality of Life Outcomes, 16(1), 109. https://doi.org/10.1186/s12955-018-0917-8
9.
ChangS. R., KenneyN. J., & ChaoY. M. (2010). Transformation in self-identity amongst Taiwanese women in late pregnancy: A qualitative study. International Journal of Nursing Studies, 47(1), 60–66. https://doi.org/10.1016/j.ijnurstu.2009.06.007
10.
Da CostaD., DritsaM., LaroucheJ., & BrenderW. (2000). Psychosocial predictors of labor/delivery complications and infant birth weight: A prospective multivariate study. Journal of Psychosomatic Obstetrics and Gynaecology, 21(3), 137–148. https://doi.org/10.3109/01674820009075621
11.
de WeerthC., & BuitelaarJ. K. (2005). Physiological stress reactivity in human pregnancy: A review. Neuroscience and Biobehavioral Reviews, 29(2), 295–312. https://doi.org/10.1016/j.neubiorev.2004.10.005
12.
DiegoM. A., FieldT., Hernandez-ReifM., CullenC., SchanbergS., & KuhnC. (2004). Prepartum, postpartum, and chronic depression effects on newborns. Psychiatry, 67(1), 63–80. https://doi.org/10.1521/psyc.67.1.63.31251
13.
ElsenbruchS., BensonS., RückeM., RoseM., DudenhausenJ., Pincus-KnackstedtM. K., KlappB. F., & ArckP. C. (2007). Social support during pregnancy: Effects on maternal depressive symptoms, smoking and pregnancy outcome. Human Reproduction, 22(3), 869–877. https://doi.org/10.1093/humrep/del432
14.
EstebsariF., KandiZ. R. K., BahabadiF. J., FilabadiZ. R., EstebsariK., & MostafaeiD. (2020). Health-related quality of life and related factors among pregnant women. Journal of Education and Health Promotion, 9, 299. https://doi.org/10.4103/jehp.jehp_307_20
15.
FreyH. A., & KlebanoffM. A. (2016). The epidemiology, etiology, and costs of preterm birth. Seminars in Fetal & Neonatal Medicine, 21(2), 68–73. https://doi.org/10.1016/j.siny.2015.12.011
16.
GhazbanzadehR., EsmaeiliShadB., MasoumifardM., & HatamipourK. (2020). The effect of positive thinking group training on psychological well-being, positive meta-emotion and couple relationship quality in nurses. Iranian Journal of Psychiatric Nursing, 7(6), 26–34. http://ijpn.ir/article-1-1448-en.html
17.
Graignic-PhilippeR., & TordjmanS. (2009). Effets du stress pendant la grossesse sur le développement du bébé et de l’enfant [Effects of stress during pregnancy on infant and child development]. Archives de pediatrie: organe officiel de la Societe francaise de pediatrie, 16(10), 1355–1363. https://doi.org/10.1016/j.arcped.2009.07.001
18.
HaasJ. S., JacksonR. A., Fuentes-AfflickE., StewartA. L., DeanM. L., BrawarskyP., & EscobarG. J. (2005). Changes in the health status of women during and after pregnancy. Journal of General Internal Medicine, 20(1), 45–51. https://doi.org/10.1111/j.1525-1497.2004.40097.x
19.
HaasJ. S., MenesesV., & McCormickM. C. (1999). Outcomes and health status of socially disadvantaged women during pregnancy. Journal of Women’s Health & Gender-Based Medicine, 8(4), 547–553. https://doi.org/10.1089/jwh.1.1999.8.547
20.
HamzehgardeshiZ., KeshvarS. G., & SorakyM. K. (2018). Health-promoting lifestyles and related factors in pregnant women. Internal Medicine and Medical Investigation Journal, 3(4), 12–17. https://api.semanticscholar.org/CorpusID:149981246
21.
HarperL. V. (2005). Epigenetic inheritance and the intergenerational transfer of experience. Psychological Bulletin, 131(3), 340–360. https://doi.org/10.1037/0033-2909.131.3.340
22.
HeamanM., KingstonD., ChalmersB., SauveR., LeeL., & YoungD. (2013). Risk factors for preterm birth and small-for-gestational-age births among Canadian women. Paediatric and Perinatal Epidemiology, 27(1), 54–61. https://doi.org/10.1111/ppe.12016
23.
HobelC., & CulhaneJ. (2003). Role of psychosocial and nutritional stress on poor pregnancy outcome. Journal of Nutrition, 133(Suppl. 2), 1709S–1717S. https://doi.org/10.1093/jn/133.5.1709S
24.
HogueC. J., & BremnerJ. D. (2005). Stress model for research into preterm delivery among black women. American Journal of Obstetrics and Gynecology, 192(5, Suppl), S47–S55. https://doi.org/10.1016/j.ajog.2005.01.073
25.
HuestonW. J., & Kasik-MillerS. (1998). Changes in functional health status during normal pregnancy. The Journal of Family Practice, 47(3), 209–212. https://pubmed.ncbi.nlm.nih.gov/9752373/
26.
IbanezG., BlondelB., PrunetC., KaminskiM., & Saurel-CubizollesM. J. (2015). Prevalence and characteristics of women reporting poor mental health during pregnancy: Findings from the 2010 French National Perinatal Survey. Revue d’epidemiologie et de Sante Publique, 63(2), 85–95. https://doi.org/10.1016/j.respe.2015.02.023
LagadecN., SteineckerM., KapassiA., MagnierA. M., ChastangJ., RobertS., GaouaouN., & IbanezG. (2018). Factors influencing the quality of life of pregnant women: A systematic review. BMC Pregnancy Childbirth, 18(1), 455. https://doi.org/10.1186/s12884-018-2087-4
29.
LobelM., Dunkel-SchetterC., & ScrimshawS. C. (1992). Prenatal maternal stress and prematurity: A prospective study of socioeconomically disadvantaged women. Health Psychology, 11(1), 32–40. https://psycnet.apa.org/doi/10.1037/0278-6133.11.1.32
30.
LuM. C., & HalfonN. (2003). Racial and ethnic disparities in birth outcomes: A life-course perspective. Maternal and Child Health Journal, 7(1), 13–30. https://doi.org/10.1023/a:1022537516969
31.
LyubomirskyS., & LayousK. (2013). How do simple positive activities increase well-being?Current Directions in Psychological Science, 22(1), 57–62. https://doi.org/10.1177/0963721412469809
32.
MaccariS., DarnauderyM., Morley-FletcherS., ZuenaA. R., CinqueC., & Van ReethO. (2003). Prenatal stress and long-term consequences: Implications of glucocorticoid hormones. Neuroscience & Biobehavioral Reviews, 27(1–2), 119–127. https://doi.org/10.1016/S0149-7634(03)00014-9
33.
MckeeM. D., CunninghamM., JankowskiK. R., & ZayasL. (2001). Health-related functional status in pregnancy: Relationship to depression and social support in a multi-ethnic population. Obstetrics & Gynecology, 97(6), 988–993. https://doi.org/10.1016/S0029-7844(01)01377-1
34.
MirghafourvandM., Mohammad-Alizadeh-CharandabiS., JafarabadiM. A., ShiriF., & Ghanbari-HomayiS. (2016). Feasibility, reliability, and validity of the Iranian version of the quality of life questionnaire for pregnancy. Iranian Red Crescent Medical Journal, 18(9), e35382. https://pubmed.ncbi.nlm.nih.gov/28144461/
35.
MogosM. F., AugustE. M., Salinas-MirandaA. A., SultanD. H., & SalihuH. M. (2013). A systematic review of quality of life measures in pregnant and postpartum mothers. Applied Research in Quality of Life, 8(2), 219–250. https://doi.org/10.1007/s11482-012-9188-4
36.
MulderE. J., Robles de MedinaP. G., HuizinkA. C., Van den BerghB. R., BuitelaarJ. K., & VisserG. H. (2002). Prenatal maternal stress: Effects on pregnancy and the (unborn) child. Early Human Development, 70(1–2), 3–14. https://doi.org/10.1016/s0378-3782(02)00075-0
37.
OtchetF., CareyM. S., & AdamL. (1999). General health and psychological symptom status in pregnancy and the puerperium: What is normal?Obstetrics and Gynecology, 94(6), 935–941. https://doi.org/10.1016/s0029-7844(99)00439-1
38.
OwenD., AndrewsM. H., & MatthewsS. G. (2005). Maternal adversity, glucocorticoids and programming of neuroendocrine function and behaviour. Neuroscience and Biobehavioral Reviews, 29(2), 209–226. https://doi.org/10.1016/j.neubiorev.2004.10.004
39.
Ramírez-VélezR. (2011). Pregnancy and health-related quality of life: A cross sectional study. Columbia Medica, 42(4), 476–481. https://www.redalyc.org/articulo.oa?id=28321543008
40.
SecklJ. R. (2004). Prenatal glucocorticoids and long-term programming. European Journal of Endocrinology, 151(Suppl. 3), U49–U62. https://doi.org/10.1530/eje.0.151u049
41.
ShokrpourN., SheidaieS., AmirkhaniM., BazrafkanL., & ModrekiA. (2021). Effect of positive thinking training on stress, anxiety, depression, and quality of life among hemodialysis patients: A randomized controlled clinical trial. Journal of Education and Health Promotion, 10, 225. https://doi.org/10.4103/jehp.jehp_1120_20
42.
StantonA. L., LobelM., SearsS., & DeLucaR. S. (2002). Psychosocial aspects of selected issues in women’s reproductive health: Current status and future directions. Journal of Consulting and Clinical Psychology, 70(3), 751–770. https://doi.org/10.1037/0022-006X.70.3.751
43.
VartikaJ., & SinghA. K. (2022). Assessment of patients health-related quality of life during complications of pregnancy in a tertiary care teaching hospital: A prospective study (Pre-print). Research Square. https://doi.org/10.21203/rs.3.rs-1207605/v1
44.
WadhwaP. D. (2005). Psychoneuroendocrine processes in human pregnancy influence fetal development and health. Psychoneuroendocrinology, 30(8), 724–743. https://doi.org/10.1016/j.psyneuen.2005.02.004
45.
WadhwaP. D., CulhaneJ. F., RauhV., & BarveS. S. (2001a). Stress and preterm birth: neuroendocrine, immune/inflammatory, and vascular mechanisms. Maternal and Child Health Journal, 5(2), 119–125. https://doi.org/10.1023/a:1011353216619
46.
WadhwaP. D., CulhaneJ. F., RauhV., BarveS. S., HoganV., SandmanC. A., HobelC. J., Chicz-DeMetA., Dunkel-SchetterC., GariteT. J., & GlynnL. (2001b). Stress, infection and preterm birth: a biobehavioural perspective. Paediatric and Perinatal Epidemiology, 15(Suppl 2), 17–29. https://doi.org/10.1046/j.1365-3016.2001.00005.x
47.
WHOQOL Group. (1995). The World Health Organization Quality of Life Assessment (WHOQOL): Position paper from the World Health Organization. Social Science & Medicine, 41(10), 1403–1409. https://doi.org/10.1016/0277-9536(95)00112-K
48.
World Bank. (1993). World development report 1993: Investing in health. Oxford University Press. http://hdl.handle.net/10986/5976
49.
World Health Organization (WHO). (2000). WHOQOL measuring quality of life. https://www.who.int/tools/whoqol/whoqol-bref
