Introduction: Jeffry Hyman (1951–2001), an introvert boy from Queens, New York City, grew up to become one of the most iconic figures in New York's punk rock scene in the mid-1970s: Joey Ramone. In this study, we explored how Joey and his family coped with his health issues and peculiar behaviors, which were eventually identified as symptoms of obsessive–compulsive disorder (OCD). Methods: A narrative review of biographical sources was conducted to explore and infer the impact of Joey's OCD on his close relationships. Results: The onset of OCD and concomitant hoarding behaviors during his teenage years profoundly disrupted family dynamics, leading to considerable burden and generating conflicts. Discussion: Joey Ramone's pathobiography and the impact of his illness on family members and close friends shed light on the intricate relationships between OCD, hoarding disorder, and family accommodation.
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