The patency of 90 elective femoropopliteal reconstructions was asessed 6 months after surgery. The preoperative white cell count was found to be a highly significant predictor of early graft failure (P < 0.0001) independent of other previously recognized predictors of occlusion such as smoking and run-off.
ErnstE, HammerschmidtDE, BaggeU, MatraiA, DormandyJA. Leucocytes and the risk of ischaemic disease. JAMA1987; 257: 2318–25.
2.
ZalokarJB, RichardJL, ClaudeJR. Leukocyte count, smoking and myocardial infarction. N Engl J Med1981; 304: 465–8.
3.
LoweGDO, JaapAJ, ForbesCD. Relation of atrial fibrillation and high haematocrit to mortality in acute stroke. Lancet1983; i: 784–6.
4.
LoweGDO, MachadoSG, KrolWF. White blood cell count and haematocrit as predictors of coronary recurrence after myocardial infarction. Thromb Haemost1985; 54: 700–3.
5.
NashGB, ThomasPRS, DormandyJA. Abnormal flow properties of white blood cells in patients with severe ischaemia of the leg. BMJ1988; 296: 1699–710.
6.
GiufettiG, MercuriM, Rizzo MariaYFlow properties of white blood cells. BMJ1988; 297: 292.
7.
BellPRF, CharlesworthD, DePalmaRGThe definition of critical ischaemia of a limb: The Working Party of the International Vascular Symposium. Br J Surg1982; 69 (Suppl): S2.
8.
ThompsonJE. Why do reported graft patency rates vary so widely? In: GreenhalghRM, Ed. Femoro-distal Bypass. London: Pitman.
9.
GloviczkiP, HillierLH. Can graft occlusion be prevented by drugs? In: GreenhalghRM, jamiesonCW, NicolaidesAN, eds. Vascular Surgery: Issues in Current Practice. London: Grune and Stratton, 1986: 37–48.
10.
EarnshawJJ, WestbyJC, MakinGS, HopkinsonBR. Defective fibrinolysis: a risk factor in early femoro-popliteal graft thrombosis. Br J Surg1987; 74: 932–5.
11.
LudwigPW, HoidalJR. Alterations in leukocyte oxidative metabolism in cigarette smokers. Am Rev Respir Dis1982; 126: 977–80.
12.
ZacharskiLR, ElvebackLR, LinmanJW. Leukocyte counts in healthy adults. Am J Clin Pathol1971; 56: 148–50.
13.
AthensJW, RaabSO, HaabOLeukokinetic studies. III. The normal distribution of granulocytes in the blood of normal subjects. J Clin Invest1961; 40: 159–64.
14.
CruikshankJM, AlexanderMK. The effect of age, sex, parity, haemoglobin level, and oral contraceptive preparations on the normal leukocyte count. Br J Haematol1970; 18: 541–50.
15.
Schmid-SchonbeinCW, Sung K-LP, TozernH.Passive mechanical properties of human leukocytes. Biophys J1981; 36: 243–56.
16.
BraideM, AmundsonB, ChienS, BaggeU.Quantitive studies on the influence of leucocytes on the vascular resistance in a skeletal muscle preparation. Microvasc Res1984; 27: 331–52.
17.
HarlanJM, KillenPD, HarkerLA. Neutrophil mediated endothelial injury in vitro. Mechanisms of cell detachment. J Clin Invest1981; 68: 1394–403.
