Leriche Memorial Lecture at 24th World Congress ‘Takayasu's Arteritis in Asia’

Abstract

An uncommon type of chronic and progressive arteritis characterized by peculiar ocular findings, an absent radial pulse and hypersensitivity of the carotid body and sinus was first described in 1908 by Takayasu, a Japanese ophthalmologist. This disorder was defined as a clinical entity by Shimizu in 1948. Takayasu's arteritis was initially thought to be confined to the Orient. Subsequent reports however indicated that this condition affected all races and has a worldwide distribution. It is also referred to as pulseless disease, aortitis syndrome, and non-specific aortoarteritis. The current widespread interest in this disease has mainly been in the Japanese literature.

Takayasu's arteritis predominates in women in the second and third decade. Recently, the classical pulseless disease has declined and symptoms resulting from hypertension and aortic regurgitation are recognised as the most important factors in prognosis.