A review of the technical features of breast cancer screening illustrated by a specific model using South Australian cancer registry data

Abstract

This paper illustrates many of the concepts and issues relating to breast cancer screening by reference to a case study of screening in South Australia and by a survey of the mathematical screening models. This work is motivated by the observation that, for some women, the prospects for a breast cancer cure appear to be enhanced if the disease is detected early. We use data from the South Australian Cancer Registry to estimate some of the parameters which describe the pattern of this disease in the South Australian female population, and the underlying model is then used to estimate the impact of various screening designs on the efficacy of a variety of breast cancer screening programmes.