Intravascular lymphoma IVL is a rare and aggressive disorder characterized by proliferation of large lymphoid cells (most commonly B-cells) within the lumen of small vessels of nearly every organ. Obliteration of vessels leads to the different clinical signs, being cutaneous lesions and neurological signs the most frequent presentations, whereas lymph node and reticuloendothelial system involvement is typically absent.1—4 No association with SLE has been described up to the present. We report a case of IVL in a patient with systemic lupus erythematosus (SLE) involving skin, central nervous system (CNS) and bone marrow. Lupus (2007) 16, 525—528.
Zuckerman D. , Seliem R., Hochberg E.Intravascular lymphoma: the oncologist's “great imitator”. Oncologist2006; 11: 496—502.
2.
Willemze R., Jaffe ES, Burg G. et al. WHO-EORTC classification for cutaneous lymphomas. Blood2005; 105: 3768—3785.
3.
Takacs I., Eros N., Bene I. et al. Successful treatment of relapse of an intravascular B-cell lymphoma with rituximab-CHOP polychemotherapy. Ann Hematol2004; 83: 608—610.
4.
Weichert G., Martinka M., Rivers JKIntravascular lymphoma presenting as telangectasias: response to rituximab and combination chemotherapy. J Cutan Med Surg2003; 7: 460—463.
5.
Bernatsky S. , Ramsey-Goldman R., Rajan R. et al. Non-Hodgkin's lymphoma in systemic lupus erythematosus. Ann Rheum Dis2005; 64: 1507—1509.
Terrier B., Aouba A., Vasiliu V. et al. Intravascular lymphoma associated with haemophagocytic syndrome: a very rare entity in western countries. Eur J Haematol2005; 75: 341—345.
