Hyperaluminaemia Associated with Oral Citrate and Aluminium Hydroxide

Abstract

1 A hospitalized patient with renal failure receiving oral aluminium hydroxide was found to have a blood aluminium level of 3124 μg/l (116 μmol/l) .

2 The extremely high aluminium concentration was attributed to the concurrent use of an oral citrate solution which converted the aluminium to a more soluble and absorbable form.

3 The combination of oral aluminium and citrate should be avoided in patients with poor renal function.

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