1 The effects of soman on the resting contractile tension of human uterine arteries, and on contractions of these arteries to vasoactive agents were investigated.
2 Soman did not alter the resting tension of helically-cut strips of human uterine arteries.
3 Soman did not alter concentration-response curves of the strips to noradrenaline, serotonin, potassium chloride or histamine.
4 Soman increased contractile tension of human uterine artery strips to subsequently added 1 μM noradrenaline.
5 It is possible that this enhancement may be involved in decreased regional blood flow following soman administration.
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