1 The results of a charcoal haemoperfusion on plasma and erythrocyte theophylline concentrations are described in a patient, intentionally intoxicated with a sustained-release theophylline formulation.
2 It is demonstrated that the charcoal-filled Gambro Adsorba 300-C column is effective in removing theophylline.
3 This effectiveness is based on pharmacokinetic parameters, which are presented.
4 The necessity of measuring plasma and erythrocyte theophylline concentrations is outlined. Calculations based on plasma theophylline concentrations only can lead to an underestimation of the effectiveness.
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