In a double-blind placebo-controlled trial using triple tetracycline (Deteclo, Lederle) 300 mg twice daily for two weeks in conjunction with metronidazole (Flagyl, May & Baker) 400 mg or matching placebo twice daily for seven days, it was shown that the addition of anti-anaerobic therapy did not significantly affect the number of cases of persistent urethritis or the relapse rate of patients with non-gonococcal urethritis (NGU).
MasfariANKinghornGRDuerdenBI.Anaerobes in genitourinary medicines in men. Br J Vener Dis1983;59:255–9.
2.
KinghornGRDuerdenBIHafizS.Clinical and microbiological investigation of women with acute salpingitis. Br J Obstet Gynaecol1986;93:869–80.
3.
KinghornGRHafizSMcEntergartMG.Pathogenic microbial flora of genital ulcers in Sheffield with particular reference to herpes simplex virus and Haemophilus ducreyi. Br J Vener Dis1982;58:377–80.
4.
MossS.Isolation and identification of anaerobic organisms from the male and female urogenital tract. Br J Vener Dis1983;59:182–5.
5.
BartonIGKinghornGRNajemSAl-OmarLSPotterCW.Incidence of herpes simplex virus types 1 and 2 isolated from patients with herpes genitalis in Sheffield. Br J Vener Dis1982;58:44–7.
6.
HolmesKKHandsworthHHWangSPAetiology of non-gonococcal urethritis. N Engl J Med1975;23:1199–205.
7.
BowieWRPollockHMForsythPSBacteriology of the urethra in normal men and men with non-gonococcal urethritis. J Clin Microbiol1977;6:482–8.
8.
SwartzSLKrausSJHermanKLStorgelMDBrownWJAllenSD.Diagnosis and aetiology of non-gonococcal urethritis. J Infect Dis1978;138:445–54.
9.
Taylor-RobinsonDEvansRTCoufalikEDPrenticeMJMundayPECsonkaGW.Ureaplasma urealyticum and Mycoplasma hominis in chlamydial and non-chlamydial non-gonococcal urethritis. Br J Vener Dis1979;55:30–5.
10.
MundayPEThomasBJJohnsonAPAltmanDGTaylor-RobinsonD.Clinical and microbiological study of non-gonococcal urethritis with particular reference to non-chlamydial disease. Br J Vener Dis1981;57:327–33.
11.
Taylor-RobinsonDCsonkaGWPrenticeMJ.Human intraurethral inoculation of ureaplasmas. Q J Med1977;183:309–26.
12.
HallenHRydenACSchwanAWallinJ.The possible role of anaerobic bacteria in the aetiology of non-gonococcal urethritis in men. Br J Vener Dis1977;53:368–71.
13.
FontaineEATaylor-RobinsonDHannaNFCoufalikED.Anaerobes in men with urethritis. Br J Vener Dis1982;58:321–6.
14.
HawkinsDAFontaineEAThomasBJBoustoullerYLTaylor-RobinsonD.The enigma of non-gonococcal urethritis: Role for Bacteroides ureolyticus. Genitourin Med1988;64:10–13.
