Lipschütz ulcers (LU) represent a challenging and frequently overlooked diagnosis within the spectrum of genital ulcerations. We present the case of a 25-year-old sexually active woman with painful ulcerative lesions on her vulva, accompanied by general malaise, fatigue, and arthralgia. She had been suffering from mild COVID-19 for 1 month. Sexually transmitted infections and cytomegalovirus were excluded. A biopsy of the lesion confirmed a Lipschütz ulcer.
GuareschiVMathevetPJacot-GuillarmodM. Ulcus Vulvae Acutum Lipschütz—uval: case series at a Swiss university hospital emergency room. Front Reprod Health2024; 5: 1333620.
2.
GayCKiharaCHaleyA, et al.Lipschütz ulcers: classic presentation of an uncommon condition. Cureus2023; 15(5): e38505.
3.
VismaraSARidolfiAFaréPB, et al.COVID-19, coronavirus vaccines, and possible association with Lipschütz vulvar ulcer: a systematic review. Clin Rev Allergy Immunol2023; 65(2): 166–171.
4.
RudolphASavageDR. Vulval aphthous ulcers in adolescents following COVID-19 vaccination—analysis of an international case series. J Pediatr Adolesc Gynecol2023, Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10020135/
5.
Bracho-BorroMGuzmán-PereraGMagañaM. Lipschütz ulcers after AstraZeneca COVID-19 vaccination. An Bras Dermatol2023; 98(5): 699–701.
6.
BrambillaIBolcatoVVolontéM, et al.Lipschütz ulcers due to SARS-CoV-2 infection: a neglected diagnosis in emergency room. Int J Womens Dermatol2024; 10(1): e122.
7.
BarnwalSPriyaDKalaPS, et al.Dysplastic changes secondary to cytomegalovirus-induced Lipschutz ulcer: unraveling complexity. Indian J Sex Transm Dis2024; 45(1): 69–71.
8.
Vieira-BaptistaPLima-SilvaJBeiresJ, et al.Lipschütz ulcers: should we rethink this? An analysis of 33 cases. Eur J Obstet Gynecol Reprod Biol2016; 198: 149–152.
9.
KayaAKayaSY. A case of COVID-19–related acute genital ulceration in a male. Int J STD AIDS2022; 33(6): 622–624.
10.
Schindler LealAAPiccinatoCABeckAPA, et al.Acute genital ulcers: keep Lipschütz ulcer in mind. Arch Gynecol Obstet2018; 298(5): 927–931.
11.
HsuTSinkJRAlanizVI, et al.Acute genital ulceration after severe acute respiratory syndrome coronavirus 2 vaccination and infection. J Pediatr2022; 246: 271–273.
