Experiment and simulation of biotissue surface thermal damage during laser surgery

Abstract

In medical cosmetology, laser energy must be properly controlled to avoid unnecessary thermal damage of normal tissue due to excessive irradiation. When a laser source is applied to a specific target that is very close to the surface tissue, residual heat can damage the surface tissue even after the laser treatment is halted. This study aims to determine the proper conditions for the laser treatment and the prediction of the thermal damage of surface tissue after the laser is applied. An 810 nm diode laser was used to irradiate porcine liver and the surface temperature was measured using infrared thermography for different laser application processes. The Pennes bioheat transfer equation was solved using the ANSYS software package to simulate the surface temperature and thermal damage zone in laser surgery. The double ellipsoid function represented the laser source term in the heat transfer simulation. The results of the simulation were compared with the experimental data. Finally, a transient analysis of the estimations of thermal damage after laser surgery was conducted for different conditions of power, laser irradiation time, and laser depth under the surface of the porcine liver.

Keywords

810 nm diode laser bio-heat transfer double ellipsoid function thermal damage effect of residual heat

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References

Proebstle

Gul

Lehr

. Infrequent early recanalization of greater saphenous vein after endovenous laser treatment. J Vasc Surg 2003; 38: 511–516.

Gibson

Ferris

Polissar

. Endovenous laser treatment of the short saphenous vein: efficacy and complications. J Vasc Surg 2007; 45: 795–803.

Proebstle

Moehler

Herdemann

. Reduced recanalization rates of the great saphenous vein after endovenous laser treatment with increased energy dosing: definition of a threshold for the endovenous fluence equivalen. J Vasc Surg 2006; 44: 834–839.

Ting

Chen

Cheng

. The prediction of skin temperature distribution in cosmetic laser surgery. Jpn J Appl Phys 2008; 47: 361–367.

Ting

Chen

. Effects of thermal energy accumulations of multi-point heat sources in laser cosmetic surgery. Proc IME E J Process Mech Eng 2014; 228: 162–167.

Jiang

Zhang

. Effects of dynamic changes of tissue properties during laser-induced interstitial thermotherapy (LITT). Lasers Med Sci 2005; 19: 197–202.

Yuan

Wang

Lee

. Estimation of the equivalent perfusion rate of Pennes model in an experimental bionic tissue without blood flow. Int Commun Heat Mass 2012; 39: 236–241.

Liu

Wang

. Analysis of thermal damage to laser irradiated tissue based on the dual-phase-lag model. Int J Heat Mass Transfer 2014; 70: 621–628.

Fasano

Hömberg

Naumov

. On a mathematical model for laser-induced thermotherapy. Appl Math Model 2010; 34: 3831–3840.

10.

Dua

Chakraborty

. A novel modeling and simulation technique of photo–thermal interactions between lasers and living biological tissues undergoing multiple changes in phase. Comput Biol Med 2005; 35: 447–462.

11.

Pfefer

Smithies

Milner

. Bioheat transfer analysis of cryogen spray cooling during laser treatment of port wine stains. Lasers Surg Med 2000; 26: 145–157.

12.

Anvari

Tanenbaum

Milner

. A theoretical study of the thermal response of skin to cryogen spray cooling and pulsed laser irradiation: implications for treatment of port wine stain birthmarks. Phys Med Biol 1995; 40: 1451–1451.

13.

Mordon

Wassmer

Zemmouri

. Mathematical modeling of 980-nm and 1320-nm endovenous laser treatment. Lasers Surg Med 2007; 39: 256–265.

14.

Mordon

Wassmer

Zemmouri

. Mathematical modeling of endovenous laser treatment (ELT). Biomed Eng Online 2006; 5: 26–26.

15.

Penne

. Analysis of tissue and arterial blood temperatures in the resting human forearm. J Appl Physiol 1948; 1: 93–122.

16.

Yilbas

. Analytical solution for time unsteady laser pulse heating of semi-infinite solid. Int J Mech Sci 1997; 39: 671–682.

17.

Kalyon

Yilbas

. Laser pulse heating: a formulation of desired temperature at the surface. Opt Lasers Eng 2003; 39: 109–119.

18.

Goldak

Chakravarti

Bibby

. A new finite element model for welding heat sources. Metall Mater Trans B 1984; 15: 299–305.

19.

Abderrazak

Bannour

Mhiri

. Numerical and experimental study of molten pool formation during continuous laser welding of AZ91 magnesium alloy. Comp Mater Sci 2009; 44: 858–866.

20.

Tsirkas

Papanikos

Kermanidis

. Numerical simulation of the laser welding process in butt-joint specimens. J Mater Process Technol 2003; 134: 59–69.

21.

Min

Zimmet

Isaacs

. Endovenous laser treatment of the incompetent greater saphenous vein. J Vasc Interv Radiol 2001; 12: 1167–1171.

22.

Kontothanassis

Mitri

Ruffino

. Endovenous laser treatment of the small saphenous vein. J Vasc Surg 2009; 49: 973–979.

23.

Zimmet

Min

. Temperature changes in perivenous tissue during endovenous laser treatment in a swine model. J Vasc Interv Radiol 2003; 14: 911–915.

24.

Zhang

Liu

. Heat transfer analysis on laser-tissue thermal interaction using heterogeneous model. Chinese J Lasers 2003; 11: 233–238.

25.

Niemz

. Laser-tissue interactions:fundamentals and applications, New York, NY: Springer, 2007, pp. 77–80.

26.

Chang

Anvari

Nelson

. Cryogen spray cooling for spatially selective photocoagulation of hemangiomas: a new methodology with preliminary clinical reports. Plast Reconstr Surg 1998; 102: 459–463.

27.

Chang

Fisher

Chen

. Intralesional photocoagulation of vascular anomalies of the tongue. Br J Plast Surg 1999; 52: 178–181.

28.

Watanabe H, Yamazaki N, Kobayashi Y, et al. Temperature dependence of thermal conductivity of liver based on various experiments and a numerical simulation for RF ablation. In: 32nd annual international conference of the IEEE engineering in medicine and biology society (EMBC), Buenos Aires, 31 August–4 September 2010, Argentina: IEEE.