The convective heat transfer in microchannels with the use of nanofluids has proved to be a potential candidate for cooling of micro-electromechanical system devices. The current research article presents the experimental study on fluid flow and heat transfer characteristics of
/water nanofluid in a microchannel under thermally developing laminar flow at Reynolds number ranging from 300 to 1000. The experimental set-up of a circular microchannel test section with an inner diameter of
and length of
is fabricated to conduct the experimental study. The effect of nanoparticle concentration (
), Reynolds number (
) on fluid flow and heat transfer characteristics of
/water nanofluid have been measured and compared with that of distilled water (DW). The results indicate that the maximum enhancement in local heat transfer coefficient is achieved up to
, while friction factor is achieved up to
for
/water nanofluid with nanoparticle concentration of
as compared to DW. The results showed that the performance evaluation criterion of
/water nanofluid is greater than unity (
), implying the benefits of nanofluids as compared to DW. Moreover, the predicted data obtained by the present proposed correlations for friction factor and local Nusselt number using
/water nanofluid show reasonably good agreement with the deviations of
and
, respectively, with the numerical data as compared to the predicted data obtained by the existing correlations available in the literature.