Given the variability of the results found in the literature, the current study is a step toward better clarifying the influence of motor and nonmotor factors on quality of life in Parkinson's disease. A total of 135 participants with Parkinson's disease were selected. Semistructured interviews were carried out, after which their mental and cognitive states were assessed using different scales (MINI, MADRS, EHD, HAMA). Finally, all participants completed 3 self-report questionnaires: 2 assessing coping strategies (WCC, CHIP) and 1, quality of life (Parkinson's disease questionnaire-39). It appears that the presence of dyskinesia, depression, and anxiety were linked to a poor quality of life. Interestingly, some different coping strategies, namely diversion as well as emotional strategies, were associated with a poor quality of life. These results encourage us to develop interventions focused on coping strategies and tailored to the emotional and clinical characteristics of each patient.
Dodel RC, Berger K., Oertel WHHealth-related quality of life and healthcare utilisation in patients with Parkinson's disease: impact of motor fluctuations and dyskinesias. Pharmacoeconomics. 2001;19:1013-1038.
2.
Péchevis M., Clarke CE, Vieregge P., et al, and Trial Study Group. Effects of dyskinesias in Parkinson's disease on quality of life and health-related costs: a prospective European study. Eur J Neurol. 2005;12:956-963.
3.
Gomez-Esteban JC, Zarranz JJ, Lezcano E., et al. Influence of motor symptoms upon the quality of life of patients with Parkinson's disease . Eur Neurol. 2007;57:161-165.
4.
Woitalla D., Mueller T., Russ H., Hock K., Haeger DAThe management approaches to dyskinesia vary from country to country . Neuroepidemiology. 2007;29:163-169.
5.
McDonald WM, Richard IH, Delong MRPrevalence, etiology, and treatment of depression in Parkinson's disease . Biol Psychiatry. 2003;54:363-375.
6.
Samii A., Nutt JG, Ransom BRParkinson's disease. Lancet. 2004;363:1783-1793.
7.
Lieberman A.Depression in Parkinson's disease: a review . Acta Neurol Scand . 2006;113:1-8.
8.
Hantz P., Caradoc-Davies G., Caradoc-Davies T., Weatherall M., Dixon G.Depression in Parkinson's disease. Am J Psychiatry . 1994;151:1010-1014.
9.
Ranoux D.Depression and Parkinson'disease. Encephale. 2000;26:22-26.
10.
Veazey C., Aki SO, Cook KF, Lai EC, Kunik MEPrevalence and treatment of depression in Parkinson's disease. J Neuropsychiatry Clin Neurosci. 2005;17:310-323.
11.
Richard IH, Frank S., McDermott MP, et al. The ups and downs of Parkinson's disease: a prospective study mood and anxiety fluctuations. Cogn Behav Neurol. 2004;17: 201-207.
12.
Menza MA, Robertson-Hoffman DE, Bonapace ASParkinson's disease and anxiety: comorbidity with depression. Biol Psychiatry. 1993;34:465-470.
13.
Lovatt B.An overview of quality of life assessments and outcome measures. Br J Med Econ. 1992;4:1-7.
14.
Slawek J., Derejko M., Lass P.Factors affecting the quality of life of patients with idiopathic Parkinson's disease-a cross-sectional study in an outpatient clinic attendees. Parkinsonism Relat Disord. 2005;11:465-468.
15.
Lazarus R., Folkman S.1984. Stress, appraisal and coping. New York : Springer.
16.
Endler NS, Parker JDA, Summerfelt LJCoping with health problems: developing a reliable and valid multidimensional measure. Psychol Assess. 1998;10:195-205.
17.
Frazier LDCoping with disease-related stressors in Parkinson's disease. Gerontologist. 2000;40:53-63.
18.
Frazier LDStability and change in patterns of coping with Parkinson's disease . Int J Aging Hum Dev. 2002;55: 207-231.
19.
Schreurs KMG , De Ridder DTD, Bensing JMA one year study of coping, social support and quality of life in Parkinson's disease. Psychol Health . 2003;15:109-121.
20.
Backer JHStressors, social support, coping, and health dysfunction in individuals with Parkinson's disease. J gerontol Nurs. 2000 ;26:6-16.
21.
Montel S., Bungener C.Coping and quality of life in one hundred and thirty-five subjects with multiple sclerosis. Mult Scler. 2007;13:393-401.
22.
Pucheu S., Consoli SM, D'Auzac C., Français P., Issad B.Do health causal attributions and coping strategies act as moderators of quality of life in peritoneal dialysis patients?J Psychosom Res. 2004;56:317-322.
23.
Daniel SE, Lees AJParkinson's Disease Society Brain Bank, London: overview and research. J Neural Transm Suppl. 1993;39:165-172.
24.
Folstein MF , Folstein SE, Mc Hugh PRMini mental scale: a practical method for grading the cognitive state of patients for the clinician . J Psychiatr Res. 1975;12: 189-198.
25.
Hoehn M., Yahr M.Parkinsonism: onset, progression and mortality. Neurology . 1967;17:427-442.
26.
Fahn S., Elton R.Members of the UPDRS Development Committee. In: Fahn S, Marsden CD, Calne DB, Goldstein M , eds. Recent Developments in Parkinson's Disease. Vol 2. Florham Park, NJ: Macmillan Health Care Information; 1987:153-163, 293-304.
27.
Lecrubier Y., Weiller E., Hergueta T., et al. M.I.N.I. 5.0.0., French Version, DSM-IV. Sheehan DV & Lecrubier Y. 1999.
28.
American Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Revised (DSM IV-TR Washington, DC: American Psychiatric Association; 2000.
29.
Montgomery SA, Asberg M.A new depression scale designed to be sensitive to change. Brit J Psychiatry. 1979;34:382-389.
30.
Jouvent R., Vindreau C., Montreuil M., Bungener C., Widlocher D.La clinique polydimensionnelle de l'humeur dépressive. Nouvelle version de l'EHD. Psychiatr Psychobiol. 1988;3:245-253.
31.
Bungener C. , Jouvent R., Derouesné C.Affective disturbances in Alzheimer's disease . J Am Geriatric Soc. 1996; 44:1066-1071.
32.
Bungener C. , Jouvent R., Delaporte C.Psychopathological and emotional deficits in myotonic dystrophy. J Neurol Neurosurg Psychiatry. 1998;65:353-356.
33.
Bungener C. , Piquard A., Pradat PFPsychopathology in amyotrophic lateral sclerosis. A preliminary study with 27 ALS patients. Amyotroph Lateral Scler Other Motor Neuron Disord Other Motor Neuron Disord . 2005;6: 221-225.
34.
Hamilton M.The assessment of anxiety states by rating . Br J Med Psychol. 1959;32:50-55.
35.
Pichot P., Pull CB, von Frenckell R., Pull MCUne analyse factorielle de l'échelle d'appréciation de l'anxiété de Hamilton . Psychiat Fennica (Int Edn)1981:181-189.
36.
Vitaliano PP , Russo J., Carr JE, Maiuro RD, Becker J.The ways of coping check-list: revision and psychometric properties. Multivariate Behav Res. 1985;20:3-26.
37.
Paulhan I., Nuissier J., Quintard B., Cousson F., Bourgeois M.La mesure du coping. Traduction et validation de la version Française de l'échelle Vitaliano. Ann Med Psychol. 1994 ;152:292-299.
38.
Jenkinson C. , Peto V., Fitzpatrick R., et al. Self reported functioning and well-being in patients with Parkinson's disease: comparison of the short-form health survey (SF-36) and the Parkinson's disease questionnaire (PDQ-39. Age Ageing. 1995;24:505-509.
39.
Peto V., Jenkinson C., Fitzpatrick R., Greenhall R.The development and validation of a short measure of functioning and wellbeing for individuals with Parkinson's disease. Qual Life Res. 1995;4:241-248.
40.
Auquier P., Sapin C., Ziegler M., et al. Validation of the French language version of the Parkinson's disease questionnaire, PDQ-39. Rev Neurol. 2002;158:41-50.
41.
Jenkinson C. , Fitzpatrick R., Peto V., Greenhall R., Hyman N.The Parkinson's disease questionnaire (PDQ-39): development and validation of a Parkinson's disease summary index score. Age Ageing. 1997;26: 353-357.
42.
Muller T., Russ H.Levodopa, motor fluctuations and dyskinesia in Parkinson's disease. Expert Opin Pharmacother. 2006;7:1715-1730.
43.
Kuopio AM, Marttilla RJ, Helenius H. et al. The quality of life in Parkinson's disease. Mov Disord. 2000;15:216-223.
