RETRACTED: Core-shell poly(lactide-co-ε-caprolactone)-gelatin fiber scaffolds as pH-sensitive drug delivery systems

Abstract

Keywords

Anti-cancer coaxial electrospinning pH-responsive dual-drug-loaded polymer fiber

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References

Gualandi

Celli

Zucchelli

et al.

Nanohybrid materials by electrospinning. Munich, Germany: Springer International Publishing, 2014, pp.87–142.

Llorens

Ibañez

Del Valle

et al . Biocompatibility and drug release behavior of scaffolds prepared by coaxial electrospinning of poly(butylene succinate) and polyethylene glycol. Mater Sci Eng C 2015; 49: 472–484.

Weili

Jianxin

Feng

et al . Coaxial electrospun aligned tussah silk fibroin nanostructured fiber scaffolds embedded with hydroxyapatite-tussah silk fibroin nanoparticles for bone tissue engineering. Mater Sci Eng C Mater Biol Appl 2016; 58: 342–351.

Jia

Yao

et al . PCL/PEG core/sheath fibers with controlled drug release rate fabricated on the basis of a novel combined technique. Int J Pharm 2014; 469: 17–22.

Drexler

and Powell

HM.

Regulation of electrospun scaffold stiffness via coaxial core diameter. Acta Biomater 2011; 7: 1133–1139.

Duan

Geng

et al . A vascular tissue engineering scaffold with core-shell structured nano-fibers formed by coaxial electrospinning and its biocompatibility evaluation. Biomed Mater 2016; 11: 035007.

Yang

Horte

et al . A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment. Biomaterials 2014; 35: 278–286.

Tannock

and Rotin

Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989; 49: 4373–4384.

Ulbrich

Etrych

Chytil

et al . Antibody-targeted polymer-doxorubicin conjugates with pH-controlled activation. J Drug Target 2004; 12: 477–489.

10.

Chiang

Huang

Chang

et al . Doxorubicin‐loaded nanogel assemblies with pH/thermo‐triggered payload release for intracellular drug delivery. Macromol Chem Phys 2014; 215: 1332–1341.

11.

Jingwen

Shen

Bin

et al . Stable acid-responsive electrospun biodegradable fibers as drug carriers and cell scaffolds. Macromol Biosci 2013; 13: 885–892.

12.

Sang

Williams

et al . Electrospun gelatin/sodium bicarbonate and poly(lactide-co-ε-caprolactone)/sodium bicarbonate nanofibers as drug delivery systems. Mater Sci Eng C Mater Biol Appl 2017; 81: 359–365.

13.

Chen

et al . Smart multifunctional hollow microspheres for the quick release of drugs in intracellular lysosomal compartments. Angew Chem Int Ed 2011; 50: 8086–8089.

14.

Rassool

GH.

Global cancer rates could increase by 50% to 15 million by 2020. Ons News 2003; 44: 7–8.

15.

Coffey

Wang

Smith

et al . Excisional surgery for cancer cure: therapy at a cost. Lancet Oncol 2003; 4: 760–768.

16.

Grivennikov

Greten

and Karin

Immunity, inflammation, and cancer. Cell 2010; 140: 883–899.

17.

Sedghi

Shaabani

Mohammadi

et al . Biocompatible electrospinning chitosan nanofibers: a novel delivery system with superior local cancer therapy. Carbohyd Polym 2017; 159: 1–10.

18.

Qiu

Feng

et al . Doxorubicin-loaded electrospun poly(L-lactic acid)/mesoporous silica nanoparticles composite nanofibers for potential postsurgical cancer treatment. J Mater Chem B 2013; 1: 4601–4611.

19.

Moseley

Alexis Carrel, the man unknown. Journey of an idea. JAMA 1980; 244: 1119–1121.

20.

Lusis

AJ.

Atherosclerosis. Nature 2000; 407: 233

21.

Chaparro

Matusicky

Allen

et al . Biomimetic microstructural reorganization during suture retention strength evaluation of electrospun vascular scaffolds. J Biomed Mater Res 2015; 104: 1525–1534.

22.

Ino

Sju

Ollivier

et al . Evaluation of hemocompatibility and endothelialization of hybrid poly(vinyl alcohol) (PVA)/gelatin polymer films. J Biomed Mater Res 2013; 101: 1549–1559.

23.

Stasiak

Nair

and Moggridge

GD.

Mechanical strength of sutured block copolymers films for load bearing medical applications. Bio Med Mater Eng 2014; 24: 563–569.

24.

Ciprofloxacin: a quinoline antibacterial with minimal side effects. Inpharma 1985; 500: 6–7.

25.

Wang

and Dong

CM.

Synthesis, sequential crystallization and morphological evolution of well‐defined star‐shaped poly(ε‐caprolactone)‐b‐poly(L‐lactide) block copolymer. Macromol Chem Phys 2006; 207: 554–562.

26.

Kim

Jung

and Kim

SH.

A biocompatible tissue scaffold produced by supercritical fluid processing for cartilage tissue engineering. Tissue Eng

Part C Methods 2013; 19: 181–188.

27.

Sartoneva

Haaparanta

LahdesVasama

et al . Characterizing and optimizing poly-l-lactide-co-ε-caprolactone membranes for urothelial tissue engineering. J R Soc Interf 2012; 9: 3444–3454.

28.

Fernández

Etxeberria

and Sarasua

J-R.

Synthesis, structure and properties of poly(L-lactide-co- ε \ -caprolactone) statistical copolymers. J Mech Behav Biomed Mater 2012; 9: 100–112.

29.

Kim

Furuya

and Tabata

Enhancement of bone regeneration by dual release of a macrophage recruitment agent and platelet-rich plasma from gelatin hydrogels. Biomaterials 2014; 35: 214–224.

30.

Farris

Song

and Huang

Alternative reaction mechanism for the cross-linking of gelatin with glutaraldehyde. J Agric Food Chem 2010; 58: 998–1003.

31.

Chioua

Bechtel

Jafri

et al . Cold water fish gelatin films: Effects of cross-linking on thermal, mechanical, barrier, and biodegradation properties. Eur Polym J 2008; 44: 3748–3753.

32.

Kuila

Bose

Khanra

et al . Characterization and properties of in situ emulsion polymerized poly(methyl methacrylate)/graphene nanocomposites. Compos Part A 2011; 42: 1856–1861.

33.

Hashim

Man

Norakasha

et al . Potential use of Fourier transform infrared spectroscopy for differentiation of bovine and porcine gelatins. Food Chem 2010; 118: 856–860.

34.

Mafra

Santos

Siegel

et al . Packing interactions in hydrated and anhydrous forms of the antibiotic Ciprofloxacin: a solid-state NMR, X-ray diffraction, and computer simulation study. J Am Chem Soc 2012; 134: 71–74.

35.

Jaiswal

Chhabra

Soni

et al . Enhanced mechanical strength and biocompatibility of electrospun polycaprolactone-gelatin scaffold with surface deposited nano-hydroxyapatite. Mater Sci Eng C Mater Biol Appl 2013; 33: 2376–2385.

36.

Yaszemski

Payne

Hayes

et al . The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold. Tissue Eng 1995; 1: 41–52.

37.

Zhou

Cao

and Ma

A novel three-dimensional tubular scaffold prepared from silk fibroin by electrospinning. Int J Biol Macromol 2009; 45: 504–510.

38.

Edlow

and Sheldon

WH.

The pH of inflammatory exudates. Proc Soc Exp Biol Med 1971; 137: 1328–1332.

39.

Yuan

Zhao

Zhu

et al . Ibuprofen-loaded electrospun fibrous scaffold doped with sodium bicarbonate for responsively inhibiting inflammation and promoting muscle wound healing in vivo. Biomater Sci 2013; 2: 502–511.

40.

Maitland

AI.

Postoperative infection. Radiol Clin N Am 2006; 44: 439–450.

41.

Lee

Kim

et al . Normal range of the inflammation related laboratory findings and predictors of the postoperative infection in spinal posterior fusion surgery. Clin Orthop Surg 2012; 4: 269–277.

42.

Zhang

Wang

Feng

et al . Coaxial electrospinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly(epsilon-caprolactone) nanofibers for sustained release. Biomacromolecules 2006; 7: 1049–1057.

43.

Colleoni

O'neill

Goldhirsch

et al . Identifying breast cancer patients at high risk for bone metastases. J Clin Oncol 2000; 18: 3925–3935.

44.

Kim

Han

et al . CT analysis of postoperative tumor recurrence patterns in periampullary cancer. Abdom Imaging 2003; 28: 0384–0391.

45.

Ghodratollah

Anoshirvan

and Sanambar

Determination of affected risk factors on time to recurrence and death in patients with postoperative gastric cancer using copula function. J Res Health Sci 2014; 14: 52–56.

46.

Munj

Lannutti

and Tomasko

DL.

Understanding drug release from PCL/gelatin electrospun blends. J Biomater Appl 2016; 6: 933–949.

47.

Cui

Zhu

et al . Investigation of drug release and matrix degradation of electrospun poly(DL-lactide) fibers with paracetanol inoculation. Biomacromolecules 2006; 7: 1623–1629.

48.

Chin

and Neu

HC.

Post-antibiotic suppressive effect of ciprofloxacin against gram-positive and gram-negative bacteria. Am J Med 1987; 82: 58–62.

49.

Fadeeva

Schlie

Koch

et al . Femtosecond laser-induced surface structures on platinum and their effects on surface wettability and fibroblast cell proliferation. Brill 2009; 163–172.

50.

Tian

Bromberg

Lin

et al . Complexation and release of doxorubicin from its complexes with pluronic P85-b-poly (acrylic acid) block copolymers. J Control Release 2007; 121: 137–145.

51.

Cao

and Kuboyama

A biodegradable porous composite scaffold of PGA/beta-TCP for bone tissue engineering. Bone 2010; 46: 386–399.

52.

Wiltfang

Merten

Schlegel

et al . Degradation characteristics of alpha and beta tri-calcium-phosphate (TCP) in minipigs. J Biomed Mater Res 2002; 63: 115–121.