The so-called bioactive ceramics have been attractive because they spontaneously bond to living bone. Organic—inorganic hybrids consisting of organic polymers and the essential constituents of the bioactive ceramics, i.e., silanol (Si—OH) group and calcium ions (Ca2+), are useful as novel bone substitutes, owing to bioactivity and high flexibility. In the present study, organic—inorganic hybrids are synthesized from chitin by modification with glycidoxypropyltrimethoxysilane (GPS) and calcium chloride (CaCl2). Their apatite-forming ability is examined in a simulated body fluid (SBF). The prepared hybrids form apatite on their surfaces in SBF within 7 days.
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