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Abstract

The COVID-19 pandemic has negatively impacted the well-being of healthcare workers (HCWs). HCWs are highly exposed to shift work and their work schedules have been subject to increasing unpredictability since the start of the pandemic. This review aims to: (1) map the studies providing information about factors associated with sleep characteristics in HCWs working in the context of the COVID-19 pandemic during the first and second waves and (2) examine the state of the evidence base in terms of the availability of information on the influence of atypical work schedules. A literature search was performed in PubMed. Studies containing information about factors (demographic; psychological; occupational; COVID-19-specific; work schedule; lifestyle; medical; or other) associated with various sleep characteristics among HCWs working in the context of the COVID-19 pandemic were included. Particular attention was paid to the availability of information on the role of atypical work schedules on HCW sleep. Fifty-seven articles met the inclusion criteria. Most studies were reports of quantitative cross-sectional surveys using self-report measures. Associations between female sex, frontline HCW status, psychological factors, and poorer sleep were observed. Six studies included a measure of shift work in their analyses, 5 of which reported an association between shift work status and sleep. A wide range of factors were investigated, with female sex, frontline HCW status, and psychological factors repeatedly demonstrating associations with poorer sleep. Sleep was predominantly measured in terms of self-reported sleep quality or insomnia symptoms. Few studies investigated the influence of atypical work schedules on HCW sleep in the context of the COVID-19 pandemic. Research on this topic is lacking in terms of reliable and consistent measurements of sleep outcomes, longitudinal data, and knowledge about the influence of covariates such atypical work schedules, comorbidity, and medical history on HCW sleep.

Keywords

sleep atypical work schedules COVID-19 shift work insomnia

One of the occupational groups whose members experience very high levels of sleep problems are healthcare workers (HCWs). Prior to the COVID-19 pandemic, an estimated 42.7% of healthcare support workers and 38.1% of healthcare practitioners and technical workers reported short sleep duration, compared with 36.5% in the general population (Shockey and Wheaton, 2017). The incidence of sleep disorders was also elevated, with reported estimates of 3.3% prevalence among HCWs compared with 1.6% for the general population (Kim et al., 2018). Since the onset of the COVID-19 pandemic, this situation seems to have further deteriorated (Pappa et al., 2021). In a meta-analysis, Cénat et al. (2020) reported a significantly higher prevalence of insomnia symptoms in HCWs (k = 6, 36.52, 95% confidence interval [CI] = 32.99-40.20) relative to the general population (k = 8, 16.45, 95% CI = 8.39-29.74) (z = 2.69, p < 0.05). The estimated pooled prevalence rates for sleep problems among HCWs have ranged from 36% to 45% (Muller et al., 2020; Pappa et al., 2020; Jahrami et al., 2021b; Xia et al., 2021). This is of concern, as sleep-related impairment may affect the ability of HCWs to perform critical tasks related to patient care (Trockel et al., 2020).

Atypical work schedules refer to a range of irregular work schedule configurations including overtime and shift work (Barthe et al., 2011). Working shifts that impose non-standard sleep/wake times may cause shorter duration of sleep, sleep fragmentation, and sleepiness due to a conflict between the required sleep-wake cycle and the individual’s endogenous circadian system (Boivin et al., 2012; Wright et al., 2013; Boivin and Boudreau, 2014). HCWs are one of the groups with the highest exposure to shift work, with estimates as high as 40% in the European Union and 35% in Canada (Rydz et al., 2020; Vanttola et al., 2020). HCWs have experienced considerable changes to their work schedules since the start of the COVID-19 pandemic, including longer hours, more shift work, and general alterations in staff scheduling to minimize interactions between different staff members (Walton et al., 2020; Hoedl et al., 2021; Mehta et al., 2021). Studies have demonstrated that sleep loss results in more occupational injuries (e.g., injuries sustained while moving patients) and errors (e.g., medication administration) among HCWs working atypical shifts than those working regular shifts (Rogers et al., 2004; Caruso and Hitchcock, 2010; Weaver et al., 2015; Booker et al., 2018). Shift work status is thus a key factor to consider when examining sleep characteristics for HCWs in the context of the COVID-19 pandemic.

In the wake of the COVID-19 pandemic, much research on sleep problems in HCWs has rapidly emerged. Previous studies have quantified the prevalence of sleep problems and provided important summaries of risk factors for poorer sleep among HCWs such as frontline HCW status and lack of social support (Bhat and Chokroverty, 2021; Pappa et al., 2021). Yet no previous review has systematically synthesized the risk factors associated with sleep problems in HCWs. More specifically, the extent to which existing research studies account for the role of atypical work schedules in determining the associations between potential risk factors and sleep characteristics remains to be seen. Thus, the first aim of this scoping review was to assess the extent and nature of the research investigating factors associated with sleep characteristics in HCWs working in the context of the COVID-19 pandemic. The second aim of the review was to closely examine these studies based on the state of existing knowledge about the potential impact of atypical work schedules on sleep among HCWs.

Materials and Methods

This scoping review followed the methodological framework for scoping reviews (Arksey and O’Malley, 2005), and the organization of the manuscript was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews (PRISMA-ScR) checklist (Tricco et al., 2018) (see Appendix A). Scoping review methodology was used as the most suitable method for reviewing a large body of heterogeneous literature not amenable to a more precise systematic review. The project was approved by the research ethics boards of the Douglas Mental Health University Institute and that of the funding agency.

Search Strategy

A keyword search was conducted on 12 February 2021 using PubMed, and updated soon after on 26 February 2021. The search strategy was developed and categorized around 3 concepts, “COVID-19,” “health care worker,” and “sleep.” Variations for each key word were combined with the “OR” operation to maximize results, for example, “SARS-CoV-2,” “frontline health worker,” and “insomnia.” Search terms are presented in greater detail in Appendix B.

Eligibility Criteria

Eligibility criteria for the selection of articles in the present review included original research studies published in English or French that reported on factors associated with sleep among HCWs who were working in the context of the COVID-19 pandemic. Only studies in which data collection took place during either the first or the second wave of infection were included. In the present review, the first wave referred to the period from 1 February 2020 to 31 July 2020, and the second wave referred to the period from 1 August 2020 to 26 February 2021 (Looi, 2020; Vahidy et al., 2020; Fan et al., 2021; Iftimie et al., 2021; Saito et al., 2021). No geographic restrictions were imposed. Both quantitative and qualitative studies were considered. The studies of interest included samples of HCWs over 18 years of age where the majority of participants were in direct contact with persons seeking healthcare. Only studies that reported on factors potentially influencing sleep among HCWs, defined in terms of a series of characteristics including poor sleep quality, symptoms of insomnia, increased sleep latency (difficulty initiating sleep), and sleep problems or sleep dysfunction/disturbances/disruptions, were included in the present review. Studies that were measuring factors associated with burnout or fatigue only (not sleep) were excluded from the review.

Studies reporting quantitative data were required to demonstrate a statistical relationship between the factor being tested and a measure of sleep. Where qualitative data were reported, the influence of the factor on sleep had to be clearly identifiable. Study protocols or feasibility studies were not included. Articles were excluded if they were theses or dissertations, did not provide an abstract, conference presentations, or books or book chapters. Review articles were not included in the current synthesis, although the reference lists of review articles whose topic was closely related to that of the present review were screened for titles that may not have been captured by the keyword search.

Screening Procedure

After removal of duplicates, the PubMed search generated a total of 417 results. The reference lists of all relevant review articles were then screened and a further 12 records retrieved, producing a total of 429 records for review. A calibration exercise was conducted before title and abstract screening to refine the eligibility criteria. Two raters (N.P. and M.F.) separately evaluated the titles and abstracts of 10 studies for inclusion or exclusion. Inter-rater agreement was then compared. This process was repeated until sufficient inter-rater agreement was achieved (80%). At this point, the article titles and abstracts were screened for eligibility according to the established inclusion criteria. Disagreements were resolved by discussion and, where necessary, a third party (D.B.B.) was consulted. For articles meeting the inclusion criteria, the full texts were retrieved, resulting in a total of 125 articles for full-text review. The same calibration exercise that was conducted before title and abstract screening was conducted prior to beginning full-text screening. The full-text screening resulted in a total of 57 articles for the final synthesis. A flow chart detailing the study selection process is provided in Figure 1.

Figure 1.

Flow diagram of database searches and study selection illustrating factors associated with sleep.

Data Extraction

A data extraction sheet was developed that included the following: author(s), year, journal, article title, study objectives, country, participants/setting, data collection period, method, data analysis, factors measured, and main findings. All factors whose association with sleep was investigated across studies were categorized as: demographic; psychological; occupational; COVID-19-specific; work schedule; lifestyle; medical; or other. These categories were developed in consultation with the research team. For studies, particularly qualitative studies that did not explicitly describe data according to one of these categories, influencing factors were abstracted by the first author and assigned to a category. A calibration exercise was conducted to ensure sufficient inter-rater agreement (80%) on the designation of certain concepts to each category.

Results

Description of Study Samples and Contexts

Fifty-seven studies (51 quantitative, 5 qualitative and 1 mixed-methods) met the inclusion criteria. All quantitative studies were descriptive in nature and consisted of cross-sectional surveys except for a single study where sleep was measured at baseline and at 1-month follow-up using the Pittsburgh Sleep Quality Index (PSQI; Zhao et al., 2020). In 4 of the 5 qualitative studies, data were collected using semi-structured interviews carried out either in-person or virtually (e.g., using Skype) (Cui et al., 2020; Sun et al., 2020; Whelehan et al., 2021; Yıldırım et al., 2021), whereas one study did not describe how the data were collected (Fan et al., 2020). Some proportion of the sample in all studies included workers in direct contact with COVID-19 patients, although the exact percentage of individuals who were working under these conditions was not always specified. Some study samples consisted of nurses/physicians only. Other studies conducted investigations of sleep in specific samples such as anesthesiologists (Jain et al., 2020) or non-consultant hospital doctors working in a surgery department (Whelehan et al., 2021). Some studies comprised a mixture of several different types of HCWs (e.g., doctors, pharmacists, paramedics, emergency department attendants, medical technicians) (Al Ammari et al., 2020; Giardino et al., 2020; Gupta et al., 2020; He et al., 2020; Huffman et al., 2020; Khanal et al., 2020; Que et al., 2020; Robles et al., 2020; Sagaon-Teyssier et al., 2020; Sharma et al., 2020; van Roekel et al., 2020; Wang et al., 2020a; Zhang et al., 2020a). Twenty-three of the 57 studies took place in China, 12 of which occurred in the context of emergency department settings at the outbreak of the virus. Data collection for all studies took place in 2020. The most recent data collection period was between July and October 2020 (Abdellah et al., 2021).

Measurement of Sleep Characteristics

Most studies used self-report instruments to measure sleep in terms of insomnia symptoms and/or sleep quality. As expected, there was heterogeneity in the measures of sleep utilized across studies. The Insomnia Severity Index (ISI) was the sleep measure most frequently adopted (Morin et al., 2011), followed by the PSQI (Buysse et al., 1989). Other measures of sleep included the Visual Analogue Sleep Scale (Snyder-Halpern and Verran, 1987; Verran and Snyder-Halpern, 1988) and the Athens Insomnia Scale (AIS) (Soldatos et al., 2003). A full list of instruments and sleep measures with corresponding cutoff scores (where specified) is presented in Table 1.

Table 1.

Measures of sleep characteristics adopted in included studies.

Measures of Sleep	Authors	Presentation of Cutoff Score for Insomnia or Poor Sleep (Where Provided)
Insomnia Severity Index (Morin et al., 2011)	Al Ammari et al. (2020)	Insomnia ≥8
	Cai et al. (2020a)	Insomnia ≥10
	Cai et al. (2020b)	Insomnia ≥8
	Elkholy et al. (2021)	Insomnia ≥8
	Giardino et al. (2020)	Insomnia ≥8
	Gu et al. (2022)	Insomnia ≥8
	Herrero San Martin et al. (2020)	Insomnia ≥9
	Jain et al. (2020)	Insomnia ≥8
	Khanal et al. (2020)	Insomnia ≥8
	Lai et al. (2020)	Insomnia ≥8
	Than et al. (2020)	Insomnia ≥15
	Que et al. (2020)	Insomnia ≥15
	Sagaon-Teyssier et al. (2020)	n/s
	Şahin et al. (2020)	Insomnia ≥8
	Sharma et al. (2020)	n/s
	Wańkowicz et al. (2020)	Insomnia ≥8
	Wang et al. (2020a)	Insomnia ≥8
	Yang et al. (2021)	Insomnia ≥8
	Zhang et al. (2020a)	Insomnia ≥8
	Zhang et al. (2020c)	Insomnia ≥8
	Zhou et al. (2020a)	Insomnia ≥8
Pittsburgh Sleep Quality Index (Buysse et al., 1989)	Abdellah et al. (2021)	Poor sleep quality >5
	Giardino et al. (2020)	Poor sleep quality >5
	He et al. (2020)	Sleep disturbance >7
	Herrero San Martin et al. (2020)	Poor sleep quality >7
	Huang et al. (2022)	n/s
	Jahrami et al. (2021a)	Poor sleep quality ≥5
	Korkmaz et al. (2020)	Sleep disturbance >5
	Olagunju et al. (2021)	Poor sleep quality >5
	Saracoglu et al. (2020)	n/s
	Simonetti et al. (2021)	n/s
	Stojanov et al. (2020)	n/s
	Tu et al. (2020)	Poor sleep quality ≥7
	Wang et al. (2020b)	Sleep disturbance >7
	Xiao et al. (2020)	n/s
	Yi et al. (2020)	Poor sleep quality ≥5
	Zhang et al. (2021)	n/s
	Zhao et al. (2020)	Poor sleep quality >5
	Zhou et al. (2020b)	Poor sleep quality ≥7
Visual Analogue Sleep Scale (Snyder-Halpern and Verran, 1987; Verran and Snyder-Halpern, 1988)	Karabulut et al. (2021)	n/s
Athens Insomnia Scale (Soldatos et al., 2003)	Diomidous (2020)	n/s
	Shen et al. (2021)	Insomnia ≥4
	Tselebis et al. (2020)	No insomnia <6
	Zhan et al. (2020)	No insomnia <6
Research Diagnostic Criteria (RDC) for insomnia disorder (Edinger et al., 2004)	McCall et al. (2020)	Insomnia diagnosed if there was: (1) adequate sleep opportunity and (2) ≥1 of the following: problems: falling asleep, or staying asleep, or waking too early, or poor quality sleep and (3) ≥1 of the following: fatigue, attention/memory problems, social/vocational problems, mood problems, daytime sleepiness, problems with motivation or energy, accident proneness, headaches/GI symptoms, worries about sleep Chronic insomnia if above criteria are met ≥1 month
Hamilton Rating Scale Ramos-(Brieva and Cordero-Villafafila, 1988)	Herrero San Martin et al. (2020)	n/s
Two-item version of the Sleep Condition Indicator (SCI-02) (Luik et al., 2019)	Barua et al. (2020)	Insomnia: ≤2
The Jenkins Sleep Scale Jenkins et al. (1988)	Diomidous (2020)	n/s
Sleep Quality Scale (SQS) single item measure of sleep quality (Snyder et al., 2018)	Gupta et al. (2020)	Poor sleep ≤3
	Khamis et al. (2020)	n/s
Subscales of Sleep-50 Questionnaire addressing diagnostic criteria for sleep disorders (Spoormaker et al., 2005)	Diomidous (2020)	n/s
Employee well-being measure for sleep problems (Adriaenssens et al., 2012)	van Roekel et al. (2020)	n/s
Self-Rating Sleeping Situation Scaling (SRSS) (Li, 2000)	Yang et al. (2021)	Sleep disorder ≥23
Other	Arafa et al. (2021)	“Inadequate sleeping” <6 h/day
	Huffman et al. (2020)	n/s
	Robles et al. (2020)	n/s

Abbreviation: GI = gastrointestinal.

In studies that used the ISI, scores were presented in a variety of ways. Most frequently, a global score ranging from 0 to 28 was interpreted using the following criteria: ISI scores of 0-7 indicating absence of insomnia, 8-14 indicating sub-threshold insomnia symptoms, 15-21 indicating moderate insomnia, and 22-28 indicating severe insomnia. In studies that used the PSQI, the cutoff score for poor sleep varied from >5 to >7, with one study using >10 as the cutoff (Zheng et al., 2021).

Factors Associated With Sleep

A wide range of variables were measured in terms of their association with the sleep of HCWs. An overview of the included articles as well as a summary of the factors in each study for which a relationship with a sleep characteristic was measured using a test of association (correlation or regression analysis) is presented in Table 2. Female sex, psychological factors, and job position were the factors that demonstrated the most prominent associations with sleep characteristics across studies. These specific results are reported in greater detail in this section.

Table 2.

Overview of included studies (n = 57).

Author	Design	Data Collection (Time Period)	Country and Setting	Type of HCW (n)	Factors	Mention of Atypical Work Schedules (✓/✗)
Qualitative
Cui et al. (2020)	Content analysis	Semi-structured face-to-face interviews (April-May 2020)	China, Hubei Hospitals	Nurses recruited from hospitals in Jiangsu province who voluntarily traveled to Hubei to provide support (n = 12)	Atypical work schedules Checking notifications on phone about COVID-19 news, fear of missing notifications about COVID-19	✓
Fan et al. (2020)	Thematic analysis	Interview (n/s)	China	Nurses (n = 44), transdisciplinary and non-transdisciplinary	Heavy workload, lack of training	✗
Sun et al. (2020)	Colaizzi’s phenomenological method	Interview, face-to-face or telephone interviews (January-February 2020)	China Hospital	Nurses (frontline) (n = 20)	Psychological pressure Long hours, workload Extra tasks related to COVID (training, information reporting, disinfection, and isolation) Lack of time to sleep	✗
Whelehan et al. (2021)	Thematic analysis	Semi-structured interviews (March-May 2020)	Ireland Department of surgery tertiary hospital	Non-consultant hospital doctors (n = 14)	Workload, new rota work models Dehydration related to PPE, focus on COVID-19	✗
Yıldırım et al. (2021)	Phenomenological analysis	Semi-structured interviews via Skype (May-August 2020)	Turkey hospitals and COVID-19 units	Nurses (n = 21)	Long shifts	✗
Author	Design	Data Collection (Time Period) and Sleep Measure	Country and Setting	Type of HCW (n)	Factors	Adjustment for Atypical Work Schedules (✓/✗)
Quantitative
Abdellah et al. (2021)	Univariate, multivariate	Cross-sectional survey (July-October 2020) PSQI	Egypt and Saudi Arabia Medical centers	Doctors (n = 344)	Sex, age, marital status Anxiety features, depression features Work hours COVID-19 history	✗
Al Ammari et al. (2020)	Multivariate analysis	Cross-sectional web-based survey (May-June 2020) ISI	Saudi Arabia, Health centers	HCWs (n = 720), doctors, nurses, pharmacists	Sex, age Work experience, work position	✗
Arafa et al. (2021)	Univariate and multivariate	Cross-sectional, questionnaire (April 2020) Average daily sleeping hours (<6, 6-9, or >9 h/day) <6 h/day was “inadequate sleeping”	Egypt and Saudi Arabia Hospitals	HCWs (n = 426), doctors, nurses, other	Sex, age, country Living with older adults, emotional support from family, emotional support from society , emotional support from hospital Work position, department; work experience Working hours, emergency shifts, night shifts Consumption of COVID news (≥2 p/day)*	✓
Barua et al. (2020)	Univariate and multivariate	Cross-sectional, online questionnaire (April-May 2020) Two-item version of the Sleep Condition Indicator (SCI-02)	Bangladesh Clinical settings	Frontline doctors (n = 370)	Sex Asthmatic status* Workplace resources, place of work Shifting duty Living in COVID-19-infected area*	✓
Cai et al. (2020a)	Univariate and multivariate	Cross-sectional case control, online questionnaire (February 2020) ISI	China Hospitals	HCWs, doctors, nurses, medical technicians, respiratory therapists, emergency room attendants (n = 2346), frontline (n = 1173) and non-frontline (n = 1173)	Work position*	✗
Cai et al. (2020b)	Univariate and multivariate	Cross-sectional case control, online questionnaire (February 2020) ISI	China Hospital	Nurses (n = 1330), frontline, non-frontline, Fangcang shelter hospital workers	Sex, age, marital status, living situation Uncertainty of fighting against pandemic* Work position, work experience, adequate cohabitants with suspicious symptoms, PPE, sufficient protection conditions and confidence Change in physical condition, value of online psychological information*	✗
Diomidous (2020)	Correlational	Cross-sectional, questionnaire (February-April 2020) The Jenkins Sleep Scale; Athens Insomnia Scale; sub-scales of Sleep-50-Questionnaire investigating sleep disorders according to diagnostic parameters of DSM-IV	Greece, Athens Public hospitals	Doctors and nurses (n = 204)	Physical activity	✗
Elkholy et al. (2021)	Univariate and multivariate	Cross-sectional survey (April-May 2020) ISI	Egypt Hospitals	Doctors, nurses, non-specialized nurses (n = 502)	Age*	✗
Giardino et al. (2020)	Univariate and multivariate	Cross-sectional online survey (June 2020) PSQI, ISI	Argentina	Doctors, trainee doctors, nurses, and other (technicians, phlebotomists etc.) (n = 1059)	Age, sex, living status Work sector, work position, workplace location Contact with COVID patients Sleep medication (pre-pandemic), sleep medication (post-pandemic)	✗
Gu et al. (2022)	Univariate and multivariate	Cross-sectional online survey (February 2020) ISI	China Fangcang shelter hospitals (set up specially to treat COVID patients)	Doctors and nurses (n = 522), Fangcang shelter hospital workers	Work position, work experience	✗
Gupta et al. (2020)	Univariate, multivariate, and correlational	Cross-sectional online survey (May 2020) Single-item Sleep Quality Scale (SQS)	India Public and private hospitals	Doctors, nurses, dentists, paramedic staff (n = 368)	Age, sex, marital status, education Anxiety* Work position PPE availability	✗
He et al. (2020)	Univariate, multivariate, and correlational	Cross-sectional web-based survey (Feb-May 2020) PSQI	China	Doctors, nurses, public health doctors, health-related administrators (n = 403)	Perceived effect of COVID-19 on daily life, expressions of concern through social media Consumption of COVID-19 news*, worried about spreading COVID-19 to family members, family members’ concern about being infected, possibility of being cured when infected	✗
Herrero San Martin et al. (2020)	Univariate and multivariate	Hospital-based questionnaire (March-April 2020) ISI, PSQI	Spain, Madrid Hospital	Doctors, nurses, nursing assistants, porters, cleaning staff (n = 100)	Age* Work position Shift work*	✗
Huang et al. (2022)	Univariate and multivariate	Online questionnaire (n/s) PSQI	China Fangcang hospitals	Nurses in (n = 966), Fangcang shelter hospital workers	Sex Stress perception* Work experience, no. of patients Family’s support* Patient’s trust*	✗
Jahrami et al. (2021a)	Univariate and multivariate	Cross-sectional online survey (Apr-Jul 2020) PSQI	Bahrain	Frontline and non-frontline, doctors, nurses, and allied healthcare professionals (n = 257)	Age, sex, marital status Work position	✗
Jain et al. (2020)	Univariate and multivariate	Cross-sectional (May 2020) ISI	India Hospital	Anesthesiologists (n = 512)	Age, sex, marital status Loneliness, anxiety Work position, salary deduction Increased work hours* COVID-related stress, fear of COVID-19, family exposure risk, availability of PPE, exposure to COVID-19 Food and accommodation issues	✗
Karabulut et al. (2021)	Univariate and correlation	Cross-sectional (April-July 2020) Visual Analogue Sleep Scale	Turkey Hospital	Healthcare professionals working in intensive care units (n = 210)	Perceived stress, state anxiety*, trait anxiety	✗
Khamis et al. (2020)	Univariate and multivariate	Cross-sectional, web-based survey (April 2020) Sleep quality scale	Oman Range of health care facilities	Doctors & nurses from several health care facilities, including primary health centers, polyclinics, and secondary and tertiary care hospitals (n = 402)	Anxiety, stress, well-being*	✗
Khanal et al. (2020)	Univariate & multivariate	Cross-sectional, online questionnaire (April-May 2020) ISI	Nepal A range of health facilities	Nurses, doctors, pharmacists, diagnostic personnel, paramedics, and public health practitioners (n = 475)	Age, ethnicity (Janajati), education History of medication Work position, work experience Working overtime Stigma about COVID-19 Affected district, awareness about government incentive	✗
Korkmaz et al. (2020)	Correlational	Cross-sectional, psychiatric interviews (n/s) PSQI	Turkey Outpatient clinics or emergency departments	Nurses, assistant healthcare staff, and doctors (n = 140)	Age Problem-solving skills, anxiety Quality of life	✗
Lai et al. (2020)	Univariate and multivariate	Cross-sectional, hospital-based survey (January-February 2020) ISI	China, Hubei Hospitals	Nurses and doctors (n = 1830)	Work position*	✗
Liu et al. (2020)	Correlational, univariate, and multivariate	Cross-sectional, online questionnaire (February to March 2020) ISI	China	Nurses, doctors, medical technicians (n = 606)	Sex, age, marital status, education degree, annual income Somatic disease Resilience, strength, hardiness Work position, working hours p/d*	✗
Than et al. (2020)	Univariate, multivariate	Cross-sectional survey (March-April 2020) ISI	Vietnam Hospitals	Nurses, doctors, technicians, pharmacists (n = 173)	Age Work experience* Designated COVID-19 hospital, concern contracting COVID at work, concerns about infection prevention control (IPC) at hospital, concerned about long-term quarantine/serving at the hospital*	✗
McCall et al. (2020)	Univariate	Cross-sectional survey by email (May 2020) Research Diagnostic Criteria for insomnia disorder	USA, Georgia Hospitals and clinics	Practicing doctors, advance practice providers, medical residents, and nurses (n = 573)	Sex, age* Pre-COVID-19 insomnia disorder status Work position, amount of training, increase in workload, clinical work load hours* Shift work Exposure to COVID-19 Insomnia before COVID-19	✓
Olagunju et al. (2021)	Correlation	Cross-sectional questionnaire (June-August 2020) PSQI	Nigeria Hospital	HCWs (permanent staff) (n = 303)	Psychological distress*	✗
Que et al. (2020)	Univariate, multivariate	Cross-sectional online survey (February 2020) ISI	China	Medical residents, doctors, nurses, technicians, and public health practitioners (n = 2285)	Sex, ethnicity, annual household income, region in China Work position* Attention to negative pandemic information (frequency), attention to type of pandemic information (negative), negative feedback (reports?) from families or friends who join frontline work, personal COVID status (suspected or confirmed case), willingness to join frontline work if had choice* Regular exercise, smoking, drinking*	✗
Robles et al. (2020)	Univariate, multivariate	Cross-sectional online survey (April-May 2020) Question about need for more rest time	Mexico	Nurses, psychologists, medical specialists, GPs or specialist residents, undergraduate students, social workers, paramedics (n = 5938)	Sex, age Domestic violence victim status* Work position Personal COVID status, friends and relatives COVID status Mourning the death of friends or loved ones due to COVID-19, caring for a person vulnerable to COVID-19 over the age of 65 or with a chronic disease Caring for one’s own children Need to rest	✗
Sagaon-Teyssier et al. (2020)	Univariate, multivariate	Cross-sectional self-administered questionnaire (April 2020) ISI	Mali NGO community-based HIV care centers	Doctors, pharmacy doctors, midwives, nurses, community HCW, psychosocial counselors, and other workers (n = 135)	Sex* Perceived health status PHQ-9, GAD-7 Work position, moral transgression, betrayal COVID-19 awareness index, PPE, healthcare supply No. of economically dependent family members Center characteristics, equipment in centers, drug stock-outs, HR availability	✗
Şahin et al. (2020)	Univariate, multivariate	Cross-sectional online questionnaire (April-May 2020) ISI	Turkey	Doctors, nurses, other (n = 939)	Sex* History of psychiatric illness* Work position* Taking the COVID test*	✗
Saracoglu et al. (2020)	Univariate, correlation	Cross-sectional survey written questionnaire (n/s) PSQI	Turkey Hospital	Nurses, anesthesiologists, nurse anesthetists, and staff working in the wards (n = 208)	Age* Work experience* Fear of COVID*	✗
Sharma et al. (2020)	Univariate	Cross-sectional online survey questionnaire (n/s) ISI	India Department of Obstetrics and Gynaecology	Doctors and nurses, or those indirectly involved, such as attendants, helpers, laboratory technicians, or house-keeping staff (n = 184)	Avoidant coping style*, anxiety, stress	✗
Shen et al. (2021)	Correlation	Cross-sectional online questionnaire (March 2020) Athens Insomnia Scale	China Hospital	Nurses (frontline) (n = 643)	Anxiety, stress	✗
Simonetti et al. (2021)	Correlation, multivariate	Cross-sectional questionnaire (February-April 2020) PSQI	Italy Hospitals	Nurses (n = 1005)	Sex* Anxiety, self-efficacy Department*	✗
Stojanov et al. (2020)	Univariate, multivariate, and correlational	Cross-sectional online web-based study (n/s) PSQI	Serbia Clinical Center including temporary hospitals	HCWs (n = 201)	Sex, education, married with children Mental health, depression, anxiety Health-related quality of life*	✗
Tselebis et al. (2020)	Univariate, multivariate, and correlational	Cross-sectional self-reported questionnaire (May 2020) Athens Insomnia Scale	Greece Hospital	Nurses (n = 150)	Age Stress, family support scale Work experience	✗
Tu et al. (2020)	Multivariate	Cross-sectional survey (February 2020) PSQI	China Wuhan Hospital	Conscripted frontline nurses (n = 100)	Age, education level, status as only child, marital status, have children PHQ-9*, GAD-7 Work experience	✗
van Roekel et al. (2020)	Univariate, multivariate	Cross-sectional online survey (May-Jun 2020) Three employee well-being measures: sleep problems; mental exhaustion; physical exhaustion	Netherlands Hospitals, nursing homes, homecare, mental health care, disability care, and other	HCWs (n = 7208)	Sex, age, living alone Leadership role Sufficient protective equipment	✗
Wang et al. (2020a)	Univariate, multivariate, and correlational	Cross-sectional electronic questionnaires (February 2020)	China Hospitals	Nurses, doctors, auxiliary staff (n = 1049)	Sex, education level* Anxiety* depression, stress Work position, work experience, department Exposure to COVID-19*	✗
Wang et al. (2020b)	Univariate, multivariate	Cross-sectional self-reported questionnaire (January-February 2020) PSQI	China Wuhan Children’s healthcare center	Doctors, nurses (n = 123)	Status as only child* Anxiety, depression* Work position Contact with COVID patients*	✗
Wańkowicz et al. (2020)	Univariate, multivariate	Cross-sectional survey (May 2020) ISI	Poland Hospitals	HCWs (n = 441)	Work position*	✗
Xiao et al. (2020)	Correlation, multivariate	Cross-sectional (January-February 2020) Self-reported questionnaires PSQI	China Hospitals	Nurses and doctors (n = 180)	Social support, anxiety, self-efficacy, stress*	✗
Yang et al. (2021)	Univariate, multivariate	Cross-sectional questionnaire (March 2020) ISI	China Wuhan Fangcang shelter hospitals and 7 general hospitals	Nurses and doctors (n = 1036)	Emotional self-efficacy* Working days in Wuhan, working hours per day in an isolation area, frequency of time spent in a medical area time/week Exposure to COVID-19, perceived peer exposure, peer diagnosis	✗
Yi et al. (2020)	Univariate, multivariate	Cross-sectional (April-May 2020) Online questionnaire PSQI	China Hospitals including designated hospitals treating COVID patients	Medical staff (n = 171)	Age, sex, education, marital status, geographic location Mental problems before the outbreak, depression (PHQ-9), anxiety (GAD-7), stress, post-traumatic stress symptoms, occupational pressure Occupation, working hours per day, professional title, department, hospital category Military personnel or not, anti-epidemic experience	✗
Zhan et al. (2020)	Univariate	Cross-sectional online questionnaire (March 2020) Athens Insomnia Scale	China Wuhan Hospitals	Frontline nurses (n = 1794)	Sex, age Chronic disease status Professional psychological assistance Experience with negative events* Perceived stress* Work experience* Night shift frequency* Treating COVID patients, personal protection training, occupational exposure to COVID-19, fear of COVID-19 Midday nap duration, fatigue Frequency of exercise	✓
Zhang et al. (2020a)	Univariate, multivariate	Cross-sectional questionnaire (January-February 2020) ISI	China Hospitals	Hospital staff including nurses, doctors, hospital administration, other medical staff (n = 1563)	Sex, age, education level, living situation Work position, work experience, department* Exposure to COVID-19, personal COVID-19 status, COVID status of people living with you, sufficient infection prevention training, strict self-protection for COVID-19, current protection can prevent getting infected, worried about being infected, perception of psychological support from news or social media regarding COVID-19, hours each day spent on reading information about the COVID-19 outbreak in past week; uncertainty regarding disease control*	✗
Zhang et al. (2021)	Correlation, multivariate	Cross-sectional online survey (May 2020) PSQI	China Hospitals	Nurses (n = 323)	Cognitive fusion, cognitive reappraisal, mental health problems Occupational stressors*	✗
Zhang et al. (2020c)	Univariate, multivariate	Cross-sectional survey (February-March) ISI	China, n /s	Medical health workers (n = 927)	Sex, age, marital status, living area, education, living with family Disease status Anxiety, depression, somatization, obsessive-compulsive symptoms, phobic anxiety Risk of contact with COVID patients in hospitals*	✗
Zhao et al. (2020)	Multivariate	Longitudinal, sleep measured at baseline and at 1 month follow-up, self-administered questionnaire (January-February 2020) PSQI	China Hospital	Doctors and nurses (n = 215)	Use of online CBT to manage sleep disorders* Work experience, work experience related to other infectious diseases, such as epidemic virus infections (SARS-CoV and MERS-CoV) Number of night shift days per month before screening for 2019-nCoV (before study period) Exposure to COVID-19 (number of work days in the department handling febrile patients during the month), subjective psychological stress related to 2019-nCoV infection*	✓
Zheng et al. (2021)	Univariate, multivariate	Cross-sectional online questionnaire (March 2020) PSQI	China Hospitals	Nurses, doctors, technicians (n = 207)	Age, sex, educational level Working experience, work position, type of hospital, work position Shift work Supporting Wuhan*	✓
Zhou et al. (2020a)	Univariate, multivariate	Cross-sectional online questionnaire (February-March 2020) ISI	China Hospital	Frontline hospital staff (n = 606)	Age, sex, education, marital status, family income BMI Work experience, working hours* Experienced SARS	✗
Zhou et al. (2020b)	Univariate, multivariate	Cross-sectional online survey (Feb 2020) PSQI	China Isolation unit/hospitals, or fever clinics	Doctors and nurses (n = 1931)	Age, sex, education, marital status, living status (living with family) Family support Work position, work experience Familiarity with COVID-19 exposure to COVID (contact with confirmed cases in daily work) Smoking status, alcohol consumption Ever attending a crisis response, less familiarity with crisis response less knowledge, working in outer response team in Wuhan*	✗
Mixed-methods
Huffman et al. (2020)	Qualitative and quantitative (univariate)	Cross-sectional Survey distributed in a large academic institution for departmental distribution Survey questions on sleep (n/s) (April 2020)	USA University School of Medicine encompassing 9 campuses and 17 hospitals	Attending doctor, fellow, resident, or administrator in University Indiana School of Medicine and individual health system hospitals (n = 720)	Concerns related to PPE	✗

Abbreviations: HCW = healthcare worker; HR = human ressources; PSQI = Pittsburgh Sleep Quality Index; ISI = Insomnia Severity Index; DSM-IV = Diagnostic and Statistical Manual of Mental Disorders, fourth edition; NGO = non-governmental organization; BMI = body mass index; PPE = personal protective equipment; GPs = general practitioners; GAD-7 = Generalized Anxiety Disorder-7; PHQ-9 = Patient Health Questionnaire-9; CBT = cognitive behavioral therapy; MERS-CoV = Middle East respiratory syndrome–related coronavirus; SARS-CoV = severe acute respiratory syndrome coronavirus.

Factors that demonstrated a statistically significant association with a sleep outcome (p < 0.05).

✓

Atypical work schedules (e.g., shift work, night shift frequency) were controlled for in the test of factors associated with sleep characteristics.

✗

Atypical work schedules (e.g., shift work, night shift frequency) were not controlled for in the test of factors associated with sleep characteristics.

Female Sex

Nine studies identified a significant association between female sex and poorer sleep (Giardino et al., 2020; McCall et al., 2020; Robles et al., 2020; Sagaon-Teyssier et al., 2020; Şahin et al., 2020; Stojanov et al., 2020; van Roekel et al., 2020; Zhan et al., 2020; Simonetti et al., 2021). Some studies reported stronger associations, for instance, in a sample of HCWs in Argentina (n = 1059), the odds of reporting a PSQI score greater than 5 were 6.4 times higher for females than for males, 95% CI = 4.46-9.20, and the odds of reporting an ISI score greater than 7 were 4.31 times higher for females than males (Giardino et al., 2020). Yet, in other studies, the strength of the associations was much weaker (Zhan et al., 2020; Simonetti et al., 2021).

Psychological Factors

The influence of psychological factors such as stress, as well as symptoms of anxiety and depression, on sleep was investigated in many of the studies reviewed. These variables were most often assessed using correlation analysis. Four studies reported a significant association between depressive symptoms and sleep (Stojanov et al., 2020; Tu et al., 2020; Wang et al., 2020a, 2020b). Relationships between anxiety symptoms and sleep were identified in both small (Gupta et al., 2020; Khamis et al., 2020; Korkmaz et al., 2020; Stojanov et al., 2020; Xiao et al., 2020; Abdellah et al., 2021; Karabulut et al., 2021; Shen et al., 2021) and larger study samples (Wang et al., 2020a; Simonetti et al., 2021). Associations between stress and sleep were reported in 4 studies (Huang et al., 2022; Khamis et al., 2020; Tselebis et al., 2020; Xiao et al., 2020). The influence of social support on sleep was also assessed. Results of a path analysis conducted by Xiao et al. (2020) indicated that social support provided to medical staff reduced their anxiety and stress levels, and positively affected self-efficacy but did not directly affect sleep (n = 180). A similar pattern was observed in Tselebis et al. (2020) where family support among nursing staff did not directly influence rates of sleep disturbance but followed an indirect pathway via stress (n = 150). In a sample of 285 HCWs, Que et al. (2020) found that those who reported an unwillingness to join frontline work, if given the choice, were at a greater risk of reporting symptoms of insomnia (odds ratio [OR] = 3.39, 95% CI = 1.86-6.17). In a sample of 323 nurses, cognitive fusion, defined as a process of constructing thoughts toward stressors and not being able to distinguish between thoughts and facts (Gross and John, 2003; Hayes et al., 2009), was positively associated with sleep difficulty (β = 0.148, p = 0.022) (Zhang et al., 2021). A range of other psychological factors affecting HCWs such as status of receiving professional psychological assistance, experience with negative events (Zhan et al., 2020), and history of psychiatric illness (Şahin et al., 2020) also demonstrated associations with sleep characteristics.

Job Position

Six of the 8 studies that tested frontline HCW status as a risk factor found statistically significant associations between frontline HCW status and sleep characteristics in both medium (Jahrami et al., 2021a; Wańkowicz et al., 2020) and larger sample sizes (Al Ammari et al., 2020; Cai et al., 2020a, 2020b; Que et al., 2020), with some studies reporting strong associations (Cai et al., 2020a; Que et al., 2020). Sixteen studies in the review investigated associations between some measure of work experience or seniority, and sleep. A pattern indicating a relationship between greater work experience and poorer sleep was observed—7 studies with widely ranging sample sizes reporting significant associations (Gu et al., 2022; Huang et al., 2022; Khanal et al., 2020; Than et al., 2020; Tselebis et al., 2020; Zhan et al., 2020; Zheng et al., 2021). Various types of jobs were investigated as predictors of sleep (e.g., doctor vs other; resident vs consultant). While heterogeneity among these associations was reported, 3 studies found that being a nurse was associated with poorer sleep. In multivariate regression models adjusted for age and sex, Zhou et al. (2020b) found that being a nurse was associated with poorer sleep (n = 1931), and Gu et al. (2022) observed that the OR for higher scores on the ISI was 3.03 (95% CI = 1.97-5.32) in nurses, compared with doctors (n = 522). Based on a logistic regression model conducted by Giardino et al. (2020), being a non-doctor predicted a higher score on the PSQI (n = 1095), although the analysis did not control for sex. In models adjusted for age and sex, Zhang et al. (2020a) reported that, compared with other medical staff, being a doctor was associated with less risk of insomnia symptoms (n = 1563).

Assessment of the Role of Atypical Work Schedules

Shift Work

Among the 52 quantitative studies, only 6 included some measurement of shift work status. Four of these studies used binary (yes/no) measures of shift work status (Barua et al., 2020; McCall et al., 2020; Herrero San Martin et al., 2020; Arafa et al., 2021). Zhan et al. (2020) assessed shift work in terms of frequency of night shifts per week. Zhao et al. (2020) assessed the number of night shift days per month before HCWs started screening for COVID-19 in patients. In a cross-sectional survey conducted by Zheng et al. (2021), participants were asked whether they were working shifts as usual, working more night shifts, or more day shifts. Only 5 studies that investigated other factors as predictors of sleep characteristics adjusted for shift work status in their multivariate analyses. No study sample consisted exclusively of HCWs working atypical work schedules.

Associations between shift work and poorer sleep were reported in both univariate (Arafa et al., 2021; Zheng et al., 2021) and multivariate analyses (Barua et al., 2020; Herrero San Martin et al., 2020; Zhan et al., 2020; Zheng et al., 2021). Arafa et al. (2021) found that in models adjusted for age, sex, profession, and country, individuals working nights shifts were 1.81 times more likely to sleep less than 6 h per day than those who were not working night shifts (95% CI = 1.17-2.80, n = 426). In their investigation of the factors associated with sleep among frontline HCWs (n = 100), Herrero San Martin et al. (2020) found that, after conducting univariate analyses on a range of variables, only shift work retained a significant association of the risk of obtaining worse scores on the ISI in the multivariate analysis. The same study also assessed parasomnias such as sleep terrors and confusional arousals and found that being a shift worker was associated with higher frequency of reporting such sleep-related symptoms (OR = 2.40, 95% CI = 1.06-5.42; p = 0.034), although other sleep disorders were not assessed. In a univariate analysis conducted among 207 HCWs, Zheng et al. (2021) found that working more night shifts was associated with poorer sleep quality (OR = 2.94, 95% CI = 1.37-6.31, p = 0.01). This association was retained after controlling for confounding factors, while results of the multivariate logistic regression analysis indicated that HCWs working more night shifts were 3.10 times more likely to report poorer sleep quality than those not working night shifts (95% CI = 1.31-7.34). In a multinomial logistic regression analysis, Barua et al. (2020) observed that shift work was associated with the odds of moderate sleep disturbances (2.21, 95 % CI = 1.24-3.94), but was not significantly associated with the odds of reporting insomnia (n = 370). McCall et al. (2020) conducted a study on rates and predictive factors for short-term insomnia disorder in a sample of 573 HCWs before and during the COVID-19 pandemic. Results for the overall sample suggested that the presence of shift work was not a significant risk factor for new cases of insomnia disorder during the pandemic. However, this analysis did not measure whether a change in the intensity of shift work over the course of the pandemic had an impact on sleep. One study did measure shift work status before the pandemic (Zhao et al., 2020), reporting that the number of night shifts worked per month (before starting screening for COVID-19) was not associated with sleep quality at baseline or at 1 month follow-up (n = 215). However once again, the change in intensity of shift work since the start of the pandemic and its association with sleep was not assessed. Among the qualitative findings, a sample of nurses who volunteered to work in Hubei Province during the COVID-19 pandemic described how the new shift schedules requiring night shifts disturbed their sleep (Cui et al., 2020).

Longer Working Hours

Working hours were measured in 8 quantitative studies (Jain et al., 2020; Khanal et al., 2020; Liu et al., 2020; McCall et al., 2020; Yi et al., 2020; Zhou et al., 2020a; Abdellah et al., 2021; Arafa et al., 2021). Four of these studies found that extended working hours were associated with poorer sleep. Arafa et al. (2021) found that working more than 6 h per day was associated with inadequate sleep (n = 426). Jain et al. (2020) reported that HCWs with an increase in working hours were 3.16 (95% CI = 1.48-6.74) times more likely to report an ISI score greater than or equal to 8 compared with HCWs not subject to increased working hours (n = 512). Analyses conducted by Liu et al. (2020) and Zhou et al. (2020a) reported that greater working hours were associated with a higher score on the ISI (n = 606 in both studies).

Discussion

In this scoping review, the state of research activity investigating factors associated with sleep in HCWs during the first and start of the second waves of the COVID-19 pandemic was assessed. Fifty-seven studies were included in the final synthesis. A comprehensive overview of risk factors for poor sleep, as investigated in relevant studies, was provided. This may be useful in providing clinicians with a visualization of available information on this subject and its development. The article also evaluated the extent to which the impact of atypical work schedules was considered in research investigating sleep among HCWs during the pandemic, and in so doing, identified a number of knowledge gaps in this area. The review of the literature revealed certain methodological issues regarding the measurement of sleep characteristics across the studies reviewed. A summary of the findings of this scoping review are summarized in Appendix C.

Methodological Issues

Most studies assessed sleep in terms of sleep quality or insomnia symptoms, with PSQI and ISI being the instruments most frequently adopted. Fifteen different instruments were used to measure sleep in the various studies. The choice of sleep measure may have an important impact on the generalizability and application of findings (Moul et al., 2004). There was a lack of consistency regarding the reporting of results. Some studies adopted the same measure of sleep (e.g., ISI), but their scores differed in terms of interpretation (different cutoff points) or presentation (insomnia vs insomnia symptoms) (Al Ammari et al., 2020; Cai et al., 2020b). This variation in the measurement of sleep and interpretation of sleep scores makes it difficult for clinicians to precisely distinguish risk factors for moderate sleep disruption from factors suggesting more severe cases of insomnia, which has implications for assessment and intervention. Nearly all studies assessed sleep using self-report measures. Although self-report measures are useful in assessing patient perceptions of sleep, other physiological and neurophysiological measures of sleep, such as actigraphy and polysomnography, have also demonstrated effectiveness (Girschik et al., 2012; Sadeh, 2015). Future studies on the sleep of HCWs may consider using measures such as these in addition to self-report measures. All but one quantitative study consisted of cross-sectional data, and as such, any conclusions drawn from these cross-sectional studies regarding risk factors for sleep among HCWs would be somewhat limited. Longitudinal data are needed to assert causal factors for sleep disturbances in this population. A small amount of longitudinal studies have been conducted since the present literature search was conducted (Abdalla et al., 2021; Jordan et al., 2021; Rossi et al., 2021; Topriceanu et al., 2021). Just two of these studies (Abdalla et al., 2021; Rossi et al., 2021) assessed predictors of poorer sleep over time, with similar risk factors to those identified in cross-sectional studies (e.g., frontline HCW status, more working hours) being reported. However, in contrast to the findings of cross-sectional studies, Rossi et al. (2021) reported that male sex was associated with an increase in insomnia symptoms. More longitudinal studies are needed to ascertain possible sex differences in the sleep of HCWs over time. Several studies failed to control for variables such as sleep medication status, sleep history, and comorbidity in assessing associations between the factors investigated and sleep. For instance, only one study adjusted for pre-existing insomnia status (before the pandemic) in their analyses (McCall et al., 2020). Sleep problems are also common in chronic conditions such as diabetes (Khalil et al., 2020). These and several other variables reported in many of the studies may have confounded associations between the factors investigated and sleep, such as the failure to control for hypertension or antidepressant medications. Moreover, many studies did not control for important lifestyle factors such as alcohol consumption, smoking, exercise, body mass index (BMI), and hypertension when assessing predictors of sleep (Rod et al., 2020; Romero Starke et al., 2020; Zhang et al., 2020b).

Emergent Risk Factors

As previously mentioned, most of the studies reviewed here were quantitative descriptive studies consisting of cross-sectional survey data, yet there was considerable heterogeneity across studies in terms of the methodologies, scales, and statistical analyses adopted. Thus, it was not possible to combine results, infer causality, or make conclusions about which factors have a greater influence on sleep than others. However, a number of overall patterns of association could be observed among the studies reviewed. It appears that female sex and frontline HCW status were the factors most consistently related to poorer sleep during the COVID-19 pandemic. These findings are consistent with existing studies which assert that women and frontline HCWs have been disproportionately vulnerable to mental health problems since the start of the COVID-19 pandemic (Cabarkapa et al., 2020; De Kock et al., 2021; Liu et al., 2021). Other sex differences such as COVID-19 mortality risk may also explain differences in sleep, although the increased mortality risk for males does not speak to our findings (Peckham et al., 2020). In addition to biological factors, gender issues are likely involved. Indeed, women remain more responsible for domestic tasks than men; increased child supervision due to stay-at-home orders and additional tasks related to COVID-19 such as increased household sanitization may have added to the domestic workload of women and subsequently impacted health outcomes such as sleep (Bigalke et al., 2020). Women represent almost 70% of the global healthcare workforce (Boniol et al., 2019) and may be a subgroup of HCWs in need of extra support during the pandemic. Numerous studies have also observed a relationship between psychological factors and sleep in HCWs. While the inferences that may be made based on these cross-sectional findings are limited, the results draw some attention to social support as a potentially important variable in disentangling the complex interrelationships between psychological factors and sleep among HCWs in the context of a pandemic. This is important information for sleep clinicians insofar that it highlights the importance of a biopsychosocial approach in assessing and treating health conditions that may be associated with sleep. The influence of other novel psychological phenomena, such as anxiety syndrome features associated with COVID-19, has yet to be fully understood. In the present review, there was some evidence to suggest that greater work experience or seniority was associated with poorer sleep among HCWs, although some studies also found inverse associations. Results of previous studies provide some support for an association between greater work experience and less stress (Lam et al., 1999; Casu and Giaquinto, 2018); however overall, this finding is largely consistent with the findings of more recent research, where similarly heterogeneous associations between seniority and sleep (Sigursteinsdóttir et al., 2020) and seniority and stress-related outcomes (e.g., psychological distress and burnout) (Vargas et al., 2014; Gómez-Urquiza et al., 2017) were observed in HCWs.

Age has been demonstrated as an important factor driving differences in COVID-19 mortality (O’Driscoll et al., 2021), which may have implications on sleep. However, a consistent pattern of association between age and sleep characteristics was not observed in the studies included in the present review. The relationship between these factors may also be partly obscured by the relationship between age and shift work, a relationship that requires further clarification (Ritonja et al., 2019). However, given that shift work status was not measured in the majority of studies, it is unclear how accounting for this factor would affect the relationship between work experience/seniority and shift work. Staff shortages induced by the COVID-19 pandemic have also led to increased responsibility and work scheduling changes among HCWs. More knowledge is needed to ascertain whether there is an association between work experience and sleep to identify subpopulations of HCWs who are potentially in need of extra support. As the pandemic progresses, further development of the findings presented here will be necessary to further clarify the factors influencing sleep and the general well-being of HCWs.

Atypical Work Schedules and Gaps in Knowledge

Five studies in the present review found that shift work status independently predicted poorer sleep in HCWs. Herrero San Martin et al. (2020) identified shift work as the only independent predictor of sleep in a multivariate analysis. These findings add to a considerable body of evidence asserting that shift work is a major risk factor for poorer sleep. While many studies discussed the increase in shift work during the COVID-19 pandemic, this review demonstrated that very few of the quantitative studies accounted for atypical work schedules in their statistical analyses, which may detract from the interpretive value of certain findings. For instance, despite the increased prevalence of shift work among nurses and frontline HCWs compared with other HCWs, some studies did not control for shift work status when assessing sleep characteristics for these groups (Al Ammari et al., 2020; Cai et al., 2020a, 2020b; Gu et al., 2022; Jahrami et al., 2021a; Que et al., 2020; Wang et al., 2020b; Zhou et al., 2020b). Overall, study samples did not distinguish between shift workers and non-shift workers. Even among studies in which the analyses did account for shift work status, the change in intensity or frequency of shift work, pre- versus post-pandemic, was not measured. In addition, measures of shift work status in studies included in the present review did not provide enough detail to decipher whether participants had been carrying out shift work before the pandemic, and if so, for how long. Moreover, individual variation in tolerance to shift work was not accounted for in the present analyses (Ritonja et al., 2019; Höller et al., 2021). In addition, studies in which shift work was measured did not provide information related to recovery time between shifts. Quality recovery time may have been exceptionally challenging for HCWs during the pandemic due to stressful work environments as well as extra domestic duties created by stay-at-home orders. More detailed information about shift work recovery and chronicity would help distinguish shift work disorder from normal sleep complaints due to episodic or occasional atypical shifts. Such information about the history and chronicity of shift work would be of use to clinicians in terms of diagnosis, risk assessment, and treatment for HCWs with sleep problems. A recently published study did identify a cross-sectional association between shift work and insomnia symptoms (Aslan and Dinç, 2021); however, just as with the studies included in the present review, shift work frequency or chronicity was not accounted for in measurement of the shift work variable.

The observed associations between extended working hours and poorer sleep in HCWs, as reported in the studies presented, provide some evidence of a relationship among these factors. Working hours were measured in only 8 studies, which was surprising given the considerable increase in working hours for HCWs since the start of the pandemic. Only one study examined how the work schedules of HCWs had changed over the course of the pandemic (Jain et al., 2020). The work schedules of HCWs have been subject to substantial change since the start of the pandemic (Mehta et al., 2021), yet the impact of these changes on the sleep of HCWs has yet to be thoroughly investigated. Changes in work schedule may result in greater unpredictability and a reduced sense of control for the HCW. There have been some media reports of increased mandatory overtime since the start of the pandemic, although precise statistics describing this phenomenon, and how it varies from country to country, are lacking. Perceived control is a key element in determining how an individual responds to stress at work (Johnson et al., 2006). HCWs’ perceived control over their work schedule may influence the relationship between stress and sleep. Future research on sleep among HCWs should take this into consideration.

Limitations

Certain limitations in the present scoping review must be acknowledged. The literature search was conducted in one database only (PubMed). Given the rapid advancement of COVID-19-related research, the authors chose to restrict the search to PubMed as one of the most extensive databases available to capture the greatest number of relevant titles in the shortest space of time. Despite a thorough search of this database, some relevant studies may have been overlooked (e.g., studies published in languages other than English or French). Despite efforts to calibrate the data-charting process, the categories used to organize the variables measured in the review were developed by the present authors and, as such, may be subject to disagreement from authors of articles in the review regarding the categorization or interpretation of their data. It should also be noted that the data reported on studies included in the current review were collected in the very early stages of the pandemic (first and start of the second waves of infection); therefore, the associated findings cannot be generalized to other waves of the pandemic. The fear and uncertainty attributed to the novelty of the virus at that time may have accounted for a greater impact of psychological symptoms and their sequelae (such as sleep) than would occur at the present time. Since the collection of the data in the studies included in this review, there is more information about the COVID-19 virus and vaccinations have become available in some contexts. Future syntheses of research on this topic should make efforts to understand the distinct challenges for HCWs at each wave of infection and to distinguish the associated impact on HCW well-being at each stage.

Conclusion

This article provides a systematic overview of the literature describing the factors associated with sleep among HCWs in the context of the COVID-19 pandemic during the first and start of the second waves. There is a clear need for longitudinal data to ascertain how certain risk factors impact the sleep of HCWs over time, especially those factors unique to the context of the current pandemic. In addition, efforts toward greater consistency regarding the measurement of sleep as an outcome (e.g., list of accepted measures, consensus on cutoff scores) would facilitate better appraisal and interpretation of knowledge on this topic. Existing research on factors associated with sleep in HCWs mainly consists of cross-sectional studies using self-reported measures of sleep quality or insomnia symptoms. Some evidence has indicated that female sex and frontline HCW status may be associated with poorer self-reported sleep, while other findings suggest that being a nurse or having more work experience may be associated with more sleep problems. Not surprisingly, psychological factors such as stress or symptoms of anxiety and depression appear to be related to quality of sleep among HCWs. Social support may also indirectly influence sleep through its effect on other psychological variables. Few studies have assessed the influence of atypical work schedules on sleep. The six studies in this review that measured atypical work schedules did so by asking participants about their status or frequency of shift work. There was a lack of information about changing shift schedules, history of shift work, and recovery between shifts. Given the notable changes in work schedules induced by the COVID-19 pandemic, more research is needed to obtain additional information about the influence of atypical work schedules on the sleep of HCWs.

Footnotes

Appendices

Appendix C.

Review of the research on the factors associated with COVID-19 HCW sleep: Main findings.

1. Factors demonstrating patterns of association with sleep characteristics	Female sex (Giardino et al., 2020; McCall et al., 2020; Robles et al., 2020; Sagaon-Teyssier et al., 2020; Şahin et al., 2020; Stojanov et al., 2020; van Roekel et al., 2020; Zhan et al., 2020; Simonetti et al., 2021) Frontline HCW status (Al Ammari et al., 2020; Cai et al., 2020a, 2020b; Lai et al., 2020; Que et al., 2020; Wańkowicz et al., 2020; Shen et al., 2021) Psychological factors – stress (Huang et al., 2022; Khamis et al., 2020; Tselebis et al., 2020; Wang et al., 2020a; Xiao et al., 2020; Zhan et al., 2020; Shen et al., 2021). – anxiety symptoms (Gupta et al., 2020; Khamis et al., 2020; Korkmaz et al., 2020; Stojanov et al., 2020; Wang et al., 2020a; Xiao et al., 2020; Karabulut et al., 2021; Shen et al., 2021; Simonetti et al., 2021) – depression symptoms (Lai et al., 2020; Stojanov et al., 2020; Tu et al., 2020; Wang et al., 2020a, 2020b). – social support (Tselebis et al., 2020; Xiao et al., 2020)
2. Methodological issues	Inconsistent measurements of sleep as an outcome Over-reliance on self-report measures of sleep Lack of longitudinal data
3. Gaps in knowledge	Paucity of information about the impact of shift work and pre-existing health status on HCW sleep

Abbreviation: HCW = healthcare worker.

Acknowledgements

We thank Rafael Pérez Medina Carballo for his help with the calibration of the data extraction sheet. We thank Dr. Judith Sabetti for writing assistance. A special thanks to NRC personnel Patricia Debergue and Stéphanie Grenier for their support with this project. The authors disclosed receipt of the following financial support for the research of this article: this work was supported by the National Research Council of Canada (NRC) through the Pandemic Response Challenge program (grant number PR010.1). NRC personnel took part in some meetings during which progress on the scoping review was discussed. However, they had no role in the design of this scoping review, interpretation of data, writing of the report, or decision to submit the article for publication.

Conflict Of Interest Statement

The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: D.B.B. provides consultation and medico-legal advice on shift work–related cases.

ORCID iDs

Philippe Boudreau

Diane B. Boivin

References

Abdalla

Chiuzan

Shang

Diaz

Shaw

McMurry

Cannone

Sullivan

Lee

(2021) Factors associated with insomnia symptoms in a longitudinal study among New York City healthcare workers during the COVID-19 pandemic. Int J Environ Res Public Health 18:8970.

Abdellah

Khalil

Alhafiz

(2021) Prevalence of poor sleep quality among physicians during the COVID-19 pandemic. Cureus 13:e12948.

Adriaenssens

De Gucht

Maes

(2012) The impact of traumatic events on emergency room nurses: findings from a questionnaire survey. Int J Nurs Stud 49:1411-1422.

Al Ammari

Sultana

Thomas

Al Swaidan

Al Harthi

(2020) Mental health outcomes amongst health care workers during COVID 19 pandemic in Saudi Arabia. Front Psychiatry 11:619540.

Arafa

Mohammed

Mahmoud

Elshazley

Ewis

(2021) Depressed, anxious, and stressed: what have healthcare workers on the frontlines in Egypt and Saudi Arabia experienced during the COVID-19 pandemic? J Affect Disord 278:365-371.

Arksey

O’Malley

(2005) Scoping studies: towards a methodological framework. Int J Soc Res Methodol 8:19-32.

Aslan

Dinç

(2021) Examining the relationship between nurses’ fear levels and insomnia during the COVID-19 pandemic in Turkey. Perspect Psychiatr Care 58:54-60.

Barthe

Messing

Abbas

(2011) Strategies used by women workers to reconcile family responsibilities with atypical work schedules in the service sector. Work 40:S47-S58.

Barua

Zaman

Omi

Faruque

(2020) Psychological burden of the COVID-19 pandemic and its associated factors among frontline doctors of Bangladesh: a cross-sectional study. F1000Res 9:1304.

10.

Bhat

Chokroverty

(2022) Sleep disorders and COVID-19. Sleep Med 91:253-261.

11.

Bigalke

Greenlund

Carter

(2020) Sex differences in self-report anxiety and sleep quality during COVID-19 stay-at-home orders. Biol Sex Differ 11:56.

12.

Boivin

Boudreau

(2014) Impacts of shift work on sleep and circadian rhythms. Pathol Biol (Paris) 62:292-301.

13.

Boivin

Boudreau

James

Kin

NNY

(2012) Photic resetting in night-shift work: impact on nurses’ sleep. Chronobiol Int 29:619-628.

14.

Boniol

McIsaac

Wuliji

Diallo

Campbell

(2019) Gender equity in the health workforce: analysis of 104 countries. Geneva (Switzerland): World Health Organization.

15.

Booker

Magee

Rajaratnam

SMW

Sletten

Howard

(2018) Individual vulnerability to insomnia, excessive sleepiness and shift work disorder amongst healthcare shift workers. Sleep Med Rev 41:220-233.

16.

Buysse

Reynolds

III Monk

Berman

Kupfer

(1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28:193-213.

17.

Cabarkapa

Nadjidai

Murgier

(2020) The psychological impact of COVID-19 and other viral epidemics on frontline healthcare workers and ways to address it: a rapid systematic review. Brain Behav Immun Health 8:100144.

18.

Cai

Feng

Huang

Wang

Xie

Wang

Liu

Hou

, et al. (2020a) The mental health of frontline and non-frontline medical workers during the coronavirus disease 2019 (COVID-19) outbreak in China: a case-control study. J Affect Disord 275:210-215.

19.

Cai

Cui

Liu

Gong

Liu

Wan

Yuan

Chen

, et al. (2020b) Nurses endured high risks of psychological problems under the epidemic of COVID-19 in a longitudinal study in Wuhan China. J Psychiatr Res 131:132-137.

20.

Caruso

Hitchcock

(2010) Strategies for nurses to prevent sleep-related injuries and errors. Rehabil Nurs 35:192-197.

21.

Casu

Giaquinto

(2018) Distress and demoralization of hospital nurses as a function of sources of stress and job seniority. Appl Nurs Res 43:61-63.

22.

Cénat

Blais-Rochette

Kokou-Kpolou

Noorishad

P-G

Mukunzi

McIntee

S-E

Dalexis

Goulet

M-A

Labelle

(2020) Prevalence of symptoms of depression, anxiety, insomnia, posttraumatic stress disorder, and psychological distress among populations affected by the COVID-19 pandemic: a systematic review and meta-analysis. Psychiatry Res 295:113599.

23.

Cui

Zhang

Yan

Shi

Jiang

Wang

Chu

(2020) Experiences and psychological adjustments of nurses who voluntarily supported COVID-19 patients in Hubei Province, China. Psychol Res Behav Manag 13:1135-1145.

24.

De Kock

Latham

Leslie

Grindle

Munoz

S-A

Ellis

Polson

O’Malley

(2021) A rapid review of the impact of COVID-19 on the mental health of healthcare workers: implications for supporting psychological well-being. BMC Public Health 21:104.

25.

Diomidous

(2020) Sleep and motion disorders of physicians and nurses working in hospitals facing the pandemic of COVID 19. Med Arch 74:210-215.

26.

Edinger

Bonnet

Bootzin

Doghramji

Dorsey

Espie

Jamieson

McCall

Morin

Stepanski

(2004) Derivation of research diagnostic criteria for insomnia: report of an American Academy of Sleep Medicine Work Group. Sleep 27:1567-1596.

27.

Elkholy

Tawfik

Ibrahim

Salah El-Din

Sabry

Mohammed

Hamza

Alaa

Fawzy

Ashmawy

, et al. (2021) Mental health of frontline healthcare workers exposed to COVID-19 in Egypt: a call for action. Int J Soc Psychiatry 67:522-531.

28.

Fan

Yang

Lin

Zhao

Yang

(2021) Decreased case fatality rate of COVID-19 in the second wave: a study in 53 countries or regions. Transbound Emerg Dis 68:213-215.

29.

Fan

Jiang

Zhou

Gou

(2020) A qualitative study of the vocational and psychological perceptions and issues of transdisciplinary nurses during the COVID-19 outbreak. Aging 12:12479-12492.

30.

Giardino

Huck-Iriart

Riddick

Garay

(2020) The endless quarantine: the impact of the COVID-19 outbreak on healthcare workers after three months of mandatory social isolation in Argentina. Sleep Med 76:16-25.

31.

Girschik

Fritschi

Heyworth

Waters

(2012) Validation of self-reported sleep against actigraphy. J Epidemiol 22:462-468.

32.

Gómez-Urquiza

De la Fuente-Solana

Albendin-Garcia

Vargas-Pecino

Ortega-Campos

Canadas-De

Fuente

(2017) Prevalence of burnout syndrome in emergency nurses: a meta-analysis. Crit Care Nurse 37:e1-e9.

33.

Gross

John

(2003) Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. J Pers Soc Psychol 85:348-362.

34.

Zhu

(2022) Factors associated with mental health outcomes among health care workers in the Fangcang shelter hospital in China. Int J Soc Psychiatry 68:64-72.

35.

Gupta

Sharma

Kumar

Mahajan

(2020) Anxiety and sleep disturbances among health care workers during the COVID-19 pandemic in India: cross-sectional online survey. JMIR Public Health Surveill 6:e24206.

36.

Hayes

Strosahl

Wilson

(2009) Acceptance and commitment therapy. Washington (DC): American Psychological Association.

37.

Fan

Xie

Liao

Han

Chen

Iacobucci

Lee

Lui

LMW

, et al. (2020) Mental health conditions among the general population, healthcare workers and quarantined population during the coronavirus disease 2019 (COVID-19) pandemic. Psychol Health Med 27:186-198.

38.

Herrero San Martin

Parra Serrano

Diaz Cambriles

Arias Arias

Muñoz Méndez

Del Yerro Álvarez

González Sánchez

(2020) Sleep characteristics in health workers exposed to the COVID-19 pandemic. Sleep Med 75:388-394.

39.

Hoedl

Bauer

Eglseer

(2021) Influence of nursing staff working hours on stress levels during the COVID-19 pandemic. HeilberufeScience 12:92-98.

40.

Höller

Gudjónsdottir

Valgeirsdóttir

Heimisson

(2021) The effect of age and chronotype on seasonality, sleep problems, and mood. Psychiatry Res 297:113722.

41.

Huang

Lei

Liu

Hang

Tao

Zhan

(2022) Nurses’ sleep quality of “Fangcang” hospital in China during the COVID-19 pandemic. Int J Ment Health Addict 20:789-799.

42.

Huffman

Athanasiadis

Anton

Haskett

Doster

Stefanidis

Lee

(2020) How resilient is your team? Exploring healthcare providers’ well-being during the COVID-19 pandemic. Am J Surg.

43.

Iftimie

López-Azcona

Vallverdú

Hernández-Flix

De Febrer

Parra

Hernández-Aguilera

Riu

Joven

Andreychuk

(2021) First and second waves of coronavirus disease-19: a comparative study in hospitalized patients in Reus, Spain. PLoS ONE 16:e0248029.

44.

Jahrami

BaHammam

AlGahtani

Ebrahim

Faris

AlEid

Saif

Haji

Dhahi

Marzooq

, et al. (2021a) The examination of sleep quality for frontline healthcare workers during the outbreak of COVID-19. Sleep Breath 25:503-511.

45.

Jahrami

BaHammam

Bragazzi

Saif

Faris

Vitiello

(2021b) Sleep problems during the COVID-19 pandemic by population: a systematic review and meta-analysis. J Clin Sleep Med 17:299-313.

46.

Jain

Singariya

Kamal

Kumar

Jain

Solanki

(2020) COVID-19 pandemic: psychological impact on anaesthesiologists. Indian J Anaesth 64:774-783.

47.

Jenkins

Stanton

Niemcryk

Rose

(1988) A scale for the estimation of sleep problems in clinical research. J Clin Epidemiol 41:313-321.

48.

Johnson

Brems

Mills

Neal

Houlihan

(2006) Moderating effects of control on the relationship between stress and change. Adm Policy Ment Health 33:499-503.

49.

Jordan

Shannon

Browne

Carroll

Maguire

Kerrigan

Hannan

McCarthy

Tully

Mulholland

, et al. (2021) COVID-19 Staff Wellbeing Survey: longitudinal survey of psychological well-being among health and social care staff in Northern Ireland during the COVID-19 pandemic. BJPsych Open 7:e159.

50.

Karabulut

Gürçayır

Yaman Aktaş

Kara

Kızıloğlu

Arslan

Bölükbaş

(2021) The effect of perceived stress on anxiety and sleep quality among healthcare professionals in intensive care units during the coronavirus pandemic. Psychol Health Med 26:119-130.

51.

Khalil

Power

Graham

Deschênes

Schmitz

(2020) The association between sleep and diabetes outcomes—a systematic review. Diabetes Res Clin Pract 161:108035.

52.

Khamis

Al Mahyijari

Al Lawati

Badahdah

(2020) The mental health of female physicians and nurses in Oman during the COVID-19 pandemic. Oman Med J 35:e203.

53.

Khanal

Devkota

Dahal

Paudel

Joshi

(2020) Mental health impacts among health workers during COVID-19 in a low resource setting: a cross-sectional survey from Nepal. Global Health 16:89.

54.

Kim

Lee

Yook

Hong

Lee

Yoon

Kang

(2018) Mental disorders among workers in the healthcare industry: 2014 national health insurance data. Ann Occup Environ Med 30:31-38.

55.

Korkmaz

Kazgan

Çekiç

Tartar

Balcı

Atmaca

(2020) The anxiety levels, quality of sleep and life and problem-solving skills in healthcare workers employed in COVID-19 services. J Clin Neurosci 80:131-136.

56.

Lai

Wang

Cai

Wei

Chen

, et al. (2020) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open 3:e203976.

57.

Lam

Ross

Cass

Quine

Lazarus

(1999) The impact of work related trauma on the psychological health of nursing staff: a cross sectional study. Aust J Adv Nurs 16:14-20.

58.

Levac

Colquhoun

O’Brien

(2010) S dology. Implement Sci 5:1-9.

59.

(2000) Analysis rating of sleep state of 13273 normal persons. Health Psychol J 8:351-353.

60.

Liu

Zhu

Huang

Deng

Guo

Huang

Liao

Mao

, et al. (2020) Prevalence and related factors of insomnia among Chinese medical staff in the middle and late stage of COVID-19. Front Psychiatry 11:602315.

61.

Liu

Yang

Zhang

Cai

Wang

Cai

, et al. (2021) Gender differences in mental health problems of healthcare workers during the coronavirus disease 2019 outbreak. J Psychiatr Res 137:393-400.

62.

Looi

M-K

(2020) Covid-19: is a second wave hitting Europe? BMJ 371:m4113.

63.

Luik

Machado

Siriwardena

Espie

(2019) Screening for insomnia in primary care: using a two-item version of the Sleep Condition Indicator. Br J Gen Pract 69:79-80.

64.

McCall

Mensah-Bonsu

Withers

Gibson

(2020) Short-term insomnia disorder in health care workers in an academic medical center before and during COVID-19: rates and predictive factors. J Clin Sleep Med 17:749-755.

65.

Mehta

Machado

Kwizera

Papazian

Moss

Azoulay

Herridge

(2021) COVID-19: a heavy toll on health-care workers. Lancet Respir Med 9:226-228.

66.

Morin

Belleville

Bélanger

Ivers

(2011) The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep 34:601-608.

67.

Moul

Hall

Pilkonis

Buysse

(2004) Self-report measures of insomnia in adults: rationales, choices, and needs. Sleep Med Rev 8:177-198.

68.

Muller

RAE

Stensland

RSØ

van de Velde

(2020) The mental health impact of the covid-19 pandemic on healthcare workers, and interventions to help them: a rapid systematic review. Psychiatry Res 293:113441.

69.

O’Driscoll

Dos Santos

Wang

Cummings

Azman

Paireau

Fontanet

Cauchemez

Salje

(2021) Age-specific mortality and immunity patterns of SARS-CoV-2. Nature 590:140-145.

70.

Olagunju

Bioku

Olagunju

Sarimiye

Onwuameze

Halbreich

(2021) Psychological distress and sleep problems in healthcare workers in a developing context during COVID-19 pandemic: implications for workplace wellbeing. Prog Neuropsychopharmacol Biol Psychiatry 110:110292.

71.

Pappa

Ntella

Giannakas

Giannakoulis

Papoutsi

Katsaounou

(2020) Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis. Brain Behav Immun 88:901-907.

72.

Pappa

Sakkas

Sakka

(2021) A year in review: sleep dysfunction and psychological distress in healthcare workers during the COVID-19 pandemic. Sleep Med 91:237-245.

73.

Peckham

de Gruijter

Raine

Radziszewska

Ciurtin

Wedderburn

Rosser

Webb

Deakin

(2020) Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission. Nat Commun 11:6317.

74.

Peters

Godfrey

Khalil

McInerney

Parker

Soares

(2015) Guidance for conducting systematic scoping reviews. JBI Evid Implement 13:141-146.

75.

Peters

Godfrey

McInerney

Baldini Soares

Khalil

Parker

(2017) Scoping reviews. In: Aromataris

Munn

editors. Joanna Briggs Institute reviewer’s manual. Adelaide: Joanna Briggs Institute. p. 1-24.

76.

Que

Shi

Deng

Liu

Zhang

Gong

Huang

Yuan

Yan

, et al. (2020) Psychological impact of the COVID-19 pandemic on healthcare workers: a cross-sectional study in China. General Psychiatr 33:e100259.

77.

Ramos-Brieva

Cordero-Villafafila

(1988) A new validation of the Hamilton Rating Scale for Depression. J Psychiatr Res 22:21-28.

78.

Ritonja

Aronson

Matthews

Boivin

Kantermann

(2019) Working Time Society consensus statements: individual differences in shift work tolerance and recommendations for research and practice. Ind Health 57:201-212.

79.

Robles

Rodríguez

Vega-Ramírez

Álvarez-Icaza

Madrigal

Durand

Morales-Chainé

Astudillo

Real-Ramírez

Medina-Mora

, et al. (2020) Mental health problems among healthcare workers involved with the COVID-19 outbreak. Rev Bras Psiquiatr 43:494-503.

80.

Rod

Oviedo-Trespalacios

Cortes-Ramirez

(2020) A brief-review of the risk factors for covid-19 severity. Rev Saude Publica 54:60.

81.

Rogers

Hwang

Scott

Aiken

Dinges

(2004) The working hours of hospital staff nurses and patient safety. Health Aff (Millwood) 23:202-212.

82.

Romero Starke

Petereit-Haack

Schubert

Kämpf

Schliebner

Hegewald

Seidler

(2020) The age-related risk of severe outcomes due to COVID-19 infection: a rapid review, meta-analysis, and meta-regression. Int J Environ Res Public Health 17:5974.

83.

Rossi

Socci

Jannini

Pacitti

Siracusano

Rossi

Di Lorenzo

(2021) Mental health outcomes among Italian health care workers during the COVID-19 pandemic. JAMA Network Open 4:e2136143.

84.

Rydz

Hall

Peters

(2020) Prevalence and recent trends in exposure to night shiftwork in Canada. Ann Work Expo Health 64:270-281.

85.

Sadeh

(2015) Sleep assessment methods. Monogr Soc Res Child Dev 80:33-48.

86.

Sagaon-Teyssier

Kamissoko

Yattassaye

Diallo

Rojas Castro

Delabre

Pouradier

Maradan

Bourrelly

Cissé

, et al. (2020) Assessment of mental health outcomes and associated factors among workers in community-based HIV care centers in the early stage of the COVID-19 outbreak in Mali. Health Policy Open 1:100017.

87.

Şahin

Aker

Şahin

Karabekiroğlu

(2020) Prevalence of depression, anxiety, distress and insomnia and related factors in healthcare workers during COVID-19 pandemic in Turkey. J Community Health 45:1168-1177.

88.

Saito

Asai

Matsunaga

Hayakawa

Terada

Ohtsu

Tsuzuki

Ohmagari

(2021) First and second COVID-19 waves in Japan: a comparison of disease severity and characteristics. J Infect 82:84-123.

89.

Saracoglu

Simsek

Kahraman

Bombaci

Sezen

Saracoglu

Demirhan

(2020) The psychological impact of COVID-19 disease is more severe on intensive care unit healthcare providers: a cross-sectional study. Clin Psychopharmacol Neurosci 18:607-615.

90.

Sharma

Seth

Solanki

Mishra

Srivastava

Jakhar

(2020) COVID-19 and obstetrical care: coping with new stress. Cureus 12:e12116.

91.

Shen

Zhan

Zheng

Liu

Wan

Zhou

(2021) Anxiety and its association with perceived stress and insomnia among nurses fighting against COVID-19 in Wuhan: a cross-sectional survey. J Clin Nurs 30:2654-2664.

92.

Shockey

Wheaton

(2017) Short sleep duration by occupation group—29 states, 2013-2014. MMWR Morb Mortal Wkly Rep 66:207-213.

93.

Sigursteinsdóttir

Skúladóttir

Agnarsdóttir

Halldórsdóttir

(2020) Stressful factors in the working environment, lack of adequate sleep, and musculoskeletal pain among nursing unit managers. Int J Environ Res Public Health 17:673.

94.

Simonetti

Durante

Ambrosca

Arcadi

Graziano

Pucciarelli

Simeone

Vellone

Alvaro

Cicolini

(2021) Anxiety, sleep disorders and self-efficacy among nurses during COVID-19 pandemic: a large cross-sectional study. J Clin Nurs 30:1360-1371.

95.

Snyder

Cai

DeMuro

Morrison

Ball

(2018) A new single-item sleep quality scale: results of psychometric evaluation in patients with chronic primary insomnia and depression. J Clin Sleep Med 14:1849-1857.

96.

Snyder-Halpern

Verran

(1987) Instrumentation to describe subjective sleep characteristics in healthy subjects. Res Nurs Health 10:155-163.

97.

Soldatos

Dikeos

Paparrigopoulos

(2003) The diagnostic validity of the Athens Insomnia Scale. J Psychosom Res 55:263-267.

98.

Spoormaker

Verbeek

van den Bout

Klip

(2005) Initial validation of the SLEEP-50 questionnaire. Behav Sleep Med 3:227-246.

99.

Stojanov

Malobabic

Stanojevic

Stevic

Milosevic

Stojanov

(2021) Quality of sleep and health-related quality of life among health care professionals treating patients with coronavirus disease-19. Int J Soc Psychiatry 67:175-181.

100.

Sun

Wei

Shi

Jiao

Song

Wang

You

, et al. (2020) A qualitative study on the psychological experience of caregivers of COVID-19 patients. Am J Infect Control 48:592-598.

101.

Than

Nong

Nguyen

Dong

Ngo

Doan

Nguyen

THT

Van Do

Dao

(2020) Mental health and health-related quality-of-life outcomes among frontline health workers during the peak of COVID-19 outbreak in Vietnam: a cross-sectional study. Risk Manag Healthc Policy 13:2927-2936.

102.

Topriceanu

Wong

Moon

Hughes

Chaturvedi

Conti

Bann

Patalay

Captur

(2021) Impact of lockdown on key workers: findings from the COVID-19 survey in four UK national longitudinal studies. J Epidemiol Community Health 75:955-962.

103.

Tricco

Lillie

Zarin

O’Brien

Colquhoun

Levac

Moher

Peters

Horsley

Weeks

(2018) PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Anna Intern Med 169:467-473.

104.

Trockel

Menon

Rowe

Stewart

Smith

Kim

Quinn

Lawrence

Marchalik

(2020) Assessment of physician sleep and wellness, burnout, and clinically significant medical errors. JAMA Netw Open 3:e2028111.

105.

Tselebis

Lekka

Sikaras

Tsomaka

Tassopoulos

Ilias

Bratis

Pachi

(2020) Insomnia, perceived stress, and family support among nursing staff during the pandemic crisis. Healthcare (Basel, Switzerland) 8:434.

106.

Zhou

(2020) Sleep quality and mood symptoms in conscripted frontline nurse in Wuhan, China during COVID-19 outbreak: a cross-sectional study. Medicine 99:e20769.

107.

Vahidy

Drews

Masud

Schwartz

Boom

Phillips

(2020) Characteristics and outcomes of COVID-19 patients during initial peak and resurgence in the Houston metropolitan area. JAMA 324:998-1000.

108.

van Roekel

van der Fels

IMJ

Bakker

Tummers

(2020) Healthcare workers who work with COVID-19 patients are more physically exhausted and have more sleep problems. Front Psychol 11:625626.

109.

Vanttola

Puttonen

Karhula

Oksanen

Härmä

(2020) Prevalence of shift work disorder among hospital personnel: a cross-sectional study using objective working hour data. J Sleep Res 29:e12906.

110.

Vargas

Cañadas

Aguayo

Fernández

Emilia

(2014) Which occupational risk factors are associated with burnout in nursing? A meta-analytic study. Int J Clin Health Psychol 14:28-38.

111.

Verran

Snyder-Halpern

(1988) Do patients sleep in the hospital? Appl Nurs Res 1:95.

112.

Walton

Murray

Christian

(2020) Mental health care for medical staff and affiliated healthcare workers during the COVID-19 pandemic. Eur Heart J Acute Cardiovasc Care 9:241-247.

113.

Wang

Huang

Zhang

Guo

Liu

Geng

(2020a) The psychological impact of COVID-19 pandemic on medical staff in Guangdong, China: a cross-sectional study. Psychol Med 52:884-892.

114.

Wang

Xie

Yao

Xiang

(2020b) Sleep disturbances among medical workers during the outbreak of COVID-2019. Occup Med 70:364-369.

115.

Wańkowicz

Szylińska

Rotter

(2020) Assessment of mental health factors among health professionals depending on their Contact with COVID-19 patients. Int J Environ Res Public Health 17:5849.

116.

Weaver

Patterson

Fabio

Moore

Freiberg

Songer

(2015) An observational study of shift length, crew familiarity, and occupational injury and illness in emergency medical services workers. Occup Environ Med 72:798-804.

117.

Whelehan

Connelly

Ridgway

(2021) COVID-19 and surgery: a thematic analysis of unintended consequences on performance, practice and surgical training. Surgeon 19:e20-e27.

118.

Wright

Jr Bogan

Wyatt

(2013) Shift work and the assessment and management of shift work disorder (SWD). Sleep Med Rev 17:41-54.

119.

Xia

Chen

Liu

Luo

Guo

Liu

Zhang

Liu

(2021) Prevalence of sleep disturbances and sleep quality in Chinese healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis. Front Psychiatry 12:149.

120.

Xiao

Zhang

Kong

Yang

(2020) The effects of social support on sleep quality of medical staff treating patients with coronavirus disease 2019 (COVID-19) in January and February 2020 in China. Med Sci Monit 26:e923549.

121.

Yang

Zhu

Yan

Liu

(2021) Prevalence of and risk factors associated with sleep disturbances among HPCD exposed to COVID-19 in China. Sleep Med 80:16-22.

122.

Kang

(2020) A key factor for psychosomatic burden of frontline medical staff: occupational pressure during the COVID-19 pandemic in China. Front Psychiatry 11:590101.

123.

Yıldırım

Aydoğan

Bulut

(2021) A qualitative study on the experiences of the first nurses assigned to COVID-19 units in Turkey. J Nurs Manag 29:1366-1374.

124.

Zhan

Liu

Shen

Gui

Zhang

Luo

Tao

(2020) Factors associated with insomnia among Chinese front-line nurses fighting against COVID-19 in Wuhan: a cross-sectional survey. J Nurs Manag 28:1525-1535.

125.

Zhang

Liu

Kong

Baker

Zhang

(2021) Occupational stressors, mental health, and sleep difficulty among nurses during the COVID-19 pandemic: the mediating roles of cognitive fusion and cognitive reappraisal. J Contextual Behav Sci 19:64-71.

126.

Zhang

Yang

Liu

Wang

Cai

Kang

, et al. (2020a) Survey of insomnia and related social psychological factors among medical staff involved in the 2019 novel coronavirus disease outbreak. Front Psychiatry 11:306.

127.

Zhang

Wang

Jia

Chen

Wei

Gong

Zhou

, et al. (2020b) Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China. Clin Microbiol Infect 26:767-772.

128.

Zhang

Wang

Yin

Zhao

Xue

Peng

Min

Tian

Leng

, et al. (2020c) Mental health and psychosocial problems of medical health workers during the COVID-19 epidemic in China. Psychother Psychosom 89:242-250.

129.

Zhao

Zhang

Cao

Dong

Jin

Fan

, et al. (2020) Job-related factors associated with changes in sleep quality among healthcare workers screening for 2019 novel coronavirus infection: a longitudinal study. Sleep Med 75:21-26.

130.

Zheng

Wang

Feng

Zhang

Fan

(2021) Sleep quality and mental health of medical workers during the coronavirus disease 2019 pandemic. Sleep Biol Rhythms 19:173-180.

131.

Zhou

Wang

Sun

Qian

Liu

Wang

Yang

Song

Zhou

, et al. (2020a) The prevalence and risk factors of psychological disturbances of frontline medical staff in china under the COVID-19 epidemic: workload should be concerned. J Affect Disord 277:510-514.

132.

Zhou

Yang

Shi

Song

Zhou

Zhang

Guo

Liu

, et al. (2020b) Prevalence and demographic correlates of poor sleep quality among frontline health professionals in Liaoning Province, China during the COVID-19 outbreak. Front Psychiatry 11:520.

Sleep of Healthcare Workers During the COVID-19 Pandemic and the Role of Atypical Work Schedules: A Scoping Review

Abstract

Keywords

Materials and Methods

Search Strategy

Eligibility Criteria

Screening Procedure

Data Extraction

Results

Description of Study Samples and Contexts

Measurement of Sleep Characteristics

Factors Associated With Sleep

Female Sex

Psychological Factors

Job Position

Assessment of the Role of Atypical Work Schedules

Shift Work

Longer Working Hours

Discussion

Methodological Issues

Emergent Risk Factors

Atypical Work Schedules and Gaps in Knowledge

Limitations

Conclusion

Footnotes

Appendices

Acknowledgements

Conflict Of Interest Statement

ORCID iDs

References