– Cancer of the bladder is closely correlated to life style and exposure to environmental and occupational chemical substances. This study, based on data taken from the tumour register of the Province of Ragusa for the period 1988–1992, has shown that bladder cancer is higher in terms of incidence and mortality than the national average. Epidemiological data would seem to back up the suspicion that there is a link between bladder cancer and phytopharmaceuticals, which could act as “initiator” and/or “promoter” agents according to the “carcinogenesis in two stages” theory. Further research will also be carried out with specific toxicological studies.
RussoP., FleshnerN.E., GarlandJ.A., O'SullivanM., TrambertR., FairW.R., OstroffJ.: Prevalence and patterns of tobacco use in patients with bladder cancer. AUA, Annual Convention, 1996.
2.
ShinkaT., MiyaiM., InagakiT., OguraH., OhkawaT.: Factors affecting the occurrence of urothelial tumours in dye workers exposed to aromatic amines. AUA, Annual Convention, 1996.
3.
LeissnerJ., GerberM., FischerU., MitzeM., Stein-backF., StöckleM.: Predictive value of p53 accumulation in patients with locally advanced bladder cancer. AUA, Annual Convention, 1996.
4.
BurkhardF.C., MarkwalderR., MottazA.E., ThalmannG.N., MerzV.W., StuderU.E.: Immunohistochemical staining for p53 mutations: a prognostic factor for bladder cancer progression?AUA, Annual Convention, 1996.
5.
BilimV., KawasakiT., TornitaY., TakahashiK.: Significance of simultaneous expression of BCL-2 and p53 on transitional cell cancer (TCC) for tumour malignancy. AUA, Annual Convention, 1996.
6.
MalkowiczS.B., TomaszewskiJ., LinnenbachA.,. WeinA.J., CangianoTh., McGarveyT.: p21 (WAF1-CIP1) and p53 expression in superficial and invasive transitional cell carcinoma. AUA, Annual Convention, 1996.
7.
M'LissHudson A., HumphreyP., SwansonP., WickM.R., VollmerR.T.: Use of p 53, MIB-1, EGFR, c-erbB-2, BCL-2 as prognostic markers in bladder cancer patients. AUA, Annual Convention, 1996.
8.
Schmitz-DrägerJ.B., GoebbelP., BültelH., Van RoeyenC., DieterC.G., EbertT., SchulzW.A.: Alterations of MDM2 and p53 in early bladder cancer. AUA, Annual Convention, 1996.
9.
Protocolli EPIC (European Prospective of Investigation into Cancer and nutrition).
10.
ChiaraG., GuidaS.: Il carcinoma della vescica come malattia professionale dei serricoltori. Ipotesi su dati epidemiologici. Editoriale News & Views, 1, 1996.
